5-羟基间苯二甲酸二甲酯置于水,Lithium Hydroxide,盐酸体系中,用 四氢呋喃,水 作为反应溶剂,以58%的收率获得产物5-羟基间苯二甲酸 参考文献: Compounds And Methods For Inhibiting Nhe-Mediated Antiport In The Treatment Of Disorders Associated With Fluid Retention Or Salt Overload And Gastrointestinal Tract Disorders[fr] Composés Et Procédés D'Inhibition D'Un Antiport à Médiation Par Nhe Dans Le Traitement De Troubles Associés à Une Rétention De Fluide Ou à Une Surcharge De Sel Et De Troubles Du Tractus Gastro-Intestinal 标题: Compounds And Methods For Inhibiting Nhe-Mediated Antiport In The Treatment Of Disorders Associated With Fluid Retention Or Salt Overload And Gastrointestinal Tract Disorders[fr] Composés Et Procédés D'Inhibition D'Un Antiport à Médiation Par Nhe Dans Le Traitement De Troubles Associés à Une Rétention De Fluide Ou à Une Surcharge De Sel Et De Troubles Du Tractus Gastro-Intestinal
专利号:US-6962963-B2 优先权日:2002-10-18 标题 :Enzymatic synthesis of polymers 发明人:KUMAR RAJESH; WATTERSON ARTHUR C; PARMAR VIRINDER SINGH; KUMAR JAYANT; SAMUELSON LYNNE ANN 权利人:UNIV MASSACHUSETTS 摘要:The invention relates to new methods of enzymatic synthesis of polymers such as polyorganosilicones and polyesters, and new polymers made by these methods.
专利号:US-2022089618-A1 优先权日:2019-01-29 标题:Solid-State Synthesis Of Precursors Of Metal-Organic Frameworks 发明人:MAJANO GERARDO J; FALKOWSKI JOSEPH M 权利人:EXXONMOBIL RES & ENG CO 摘要:Metal-organic frameworks (MOFs) are highly porous entities comprising a multidentate ligand coordinated to multiple metal atoms, typically as a coordination polymer. MOFs are usually produced from a solvent in powder form under hydrothermal or solvothermal synthesis conditions. Alternately, powder-form precursors of MOFs may be formed by milling or mulling a substantially solid mixture of a metal salt and a multidentate organic ligand, optionally in the presence of a small amount of a solvent. The powder-form precursors may then undergo heating, typically in the absence of applied shear, to produce the corresponding MOF. Mulling may be differentiated from milling at least in that mulling applies to the substantially solid mixture at a non-constant pressure and milling applies a constant pressure while forming the powder-form precursor. In some cases, mulling may promote more effective formation of the powder-form precursor compared to milling.
专利号:US-9157156-B2 优先权日:2009-07-07 标题 :Process for the preparation of a iodinating agent 发明人:ANELLI PIER LUCIO; VISCARDI CARLO FELICE; DELOGU PIETRO; GOFFREDI FABRIZIO; NARDELLI ALFONSO; GIOVENZANA GIOVANNI BATTISTA 权利人:ANELLI PIER LUCIO; VISCARDI CARLO FELICE; DELOGU PIETRO; GOFFREDI FABRIZIO; NARDELLI ALFONSO; GIOVENZANA GIOVANNI BATTISTA; BRACCO IMAGING SPA 摘要:The present invention describes a process for the synthesis of a iodinating agent, being said iodinating agent iodine chloride (ICI.) In particular, the present invention relates to a process for the electrochemical preparation of ICI, as a useful iodinating agent in the preparation of iodinated organic compounds for use as contrast agents or their precursors in the synthesis of the same.
专利号:US-6180830-B1 优先权日:1995-11-08 标题 :Method for preparing a bimetallic ruthenium/tin catalyst and a process for the synthesis of aldehydes 发明人:JACQUOT ROLAND 权利人:RHODIA CHIMIE SA 摘要:The present invention relates to a new process for the preparation of a bimetallic ruthenium/tin catalyst. The process for the preparation of a bimetallic ruthenium/tin catalyst according to the invention is characterised by the fact that it consists in carrying out the reduction of a ruthenium complex having an electrovalency of -4 and a coordination number of 6, the ligands being either a halogen atom or an anion or a tin halide. The catalyst is further employed for the preparation of aldehydes by reduction, in the vapor phase, of carboxylic acids, esters and anhydrides.
专利号:US-10737239-B2 优先权日:2015-11-27 标题 :Ultrafast high space-time-yield synthesis of metal-organic frameworks 发明人:BURCKHART JULIA; MARX STEFAN; ARNOLD LENA; HOFMANN CLAUS; Müller Ulrich 权利人:BASF SE 摘要:The invention relates to a process for the preparation of metal-organic frameworks (MOFs) in form of a homogenous powder, and a process wherein the metal-organic framework is molded into shaped bodies.
专利号:US-9951095-B2 优先权日:2014-05-16 标 题:Chromium metal organic frameworks and synthesis of metal organic frameworks 发明人:ZHOU HONG-CAI; Liu tian-fu; LIAN XIZHEN; ZOU LANFANG; FENG DAWEI 权利人:TEXAS A & M UNIV SYS 摘要:The present invention relates to monocrystalline metal organic frameworks comprising chromium ions and carboxylate ligands and the use of the same, for example their use for storing a gas. The invention also relates to methods for preparing metal organic frameworks comprising chromium, titanium or iron ions and carboxylate ligands. The methods of the invention allow such metal organic frameworks to be prepared in monocrystalline or polycrystalline forms.
[参考文献]: Kaisa Hnninen, Et Al. Mechanistic Evaluation Of Factors Affecting Compound Loading Into Ion-Exchange Fibers. Eur J Pharm Sci. 2007 Aug;31(5):306-17. [参考文献]: Kaisa R Hnninen, Et Al. The Effect Of Valence On The Ion-Exchange Process: Theoretical And Experimental Aspects On Compound Binding/release. J Pharm Sci. 2007 Jan;96(1):117-31. [参考文献]: M Pravda, Et Al. Application Of Stripping Voltammetry To Trace Lead Analysis In Intermediates And Final Products Of Syntheses Of Pharmaceuticals. J Pharm Biomed Anal. 1996 May;14(7):765-71. [参考文献]: Mathias Kberl, Et Al. Dicarboxylate-Bridged (Mo2)N (N = 2, 3, 4) Paddle-Wheel Complexes: Potential Intermediate Building Blocks For Metal-Organic Frameworks. Dalton Trans. 2011 Nov 21;40(43):11490-6. [参考文献]: Zheng-Bo Han, Et Al. Two 3D Chiral Coordination Polymers With 4-Connected 6(6) Topological Net: Synthesis, Structure And Magnetic Properties. Dalton Trans. 2009 Nov 28:(44):9807-11.