CAS: 17949-65-4; Zincpicolinate

Znso4,α,2-吡啶甲酸,锌置于ice体系中,用 水 用作溶剂,化学反应 16.58H,以to Yield 200 Ml的收率获得吡啶甲酸锌
参考文献:Dietary Supplementation With Essential Metal Picolinates
标题:Dietary Supplementation With Essential Metal Picolinates
摘要:哺乳动物系统中的必需金属水平可以通过以吡啶甲酸的配位络合物形式给予这些金属来精确控制.这些络合物的结构式如下:##str1## 其中m代表金属阳离子,N等于阳离子的价态.

专利信息

专利号:US-2020054045-A1
优先权日:2008-09-03
标 题 :All-Natural Drink Composition for Synthesizing and Regenerating Adenosine Triphosphate (ATP) in Muscle Cells and Neurons, Repairing Exercise-Induced Muscle Fiber Damage, Repletion of Glycogen Stores in the Muscle and Liver, Enhancing Blood Flow to Tissue during Intense Exercise, and Preventing and Reducing Oxidative Damage to Tissues during Exercise with Minimal Gastrointestinal Disturbances
发明人：SCHMIDT MICHAEL JAMES; AVARBOCK DAVID
权利人:BIOMECHANICAL TECH LLC
摘要:The present invention provides for a nutritional composition in a liquid drink form, dry powder form, gel form, or carrier form intended to optimize human physiological performance during intense exercise and subsequently return the body to its healthy, pre-exercise state. The composition comprises a carbohydrate and a protein, and preferably a ratio of the carbohydrate to the protein is greater than about 4.3 parts by weight carbohydrate to 1 part by weight protein. Preferably, the liquid nutritional composition is comprised of: (1) carbohydrate in the range of 3.45-10% by weight of the liquid nutritional composition to allow immediate and long-term energy production by muscle cells and neurons, insulin modulation, and muscle glycogen sparing, the carbohydrate being in the form of monosaccharides or polysaccharides or a combination thereof, and the saccharides preferably comprising 40-95% dextrose by weight of the final volume of saccharides, 5-45% fructose by weight of the final volume of saccharides, and 1-25% glucose polymer by weight of the final volume of saccharides; (2) a protein source that contains all 20 “standardâ€? amino acids, in the range of 0.1-0.8% by weight of the liquid nutritional composition, whose inherent structure plus further chemical modification results in amino acid absorption into the bloodstream rapid enough for initiating and enhancing protein synthesis and subsequent muscle cell repair during the exercise and post-exercise periods; (3) Branched-Chain Amino Acids (BCAA), leucine, isoleucine, valine, for use by muscle cells for energy thus sparing glycogen stores, for increasing protein synthesis by stimulating insulin and growth hormone release, and for reducing protein degradation; (4) precursors of the signaling molecule nitric oxide, important for increasing blood flow and subsequent nutrient delivery (including those in this composition) to tissue during intense exercise; (5) precursors of creatine, a molecule important for ATP regeneration in muscle and nerve cells and for muscle cell volumizing effects; (6) a mixture of hydrophilic and hydrophobic antioxidants: retinol/Beta-carotene (Vitamin A), ascorbic acid (Vitamin C), and di-alpha-tocopheryl acetate (Vitamin E); ubiquinone (coenzyme Q 10 [5-100 mg/500 ml], which in addition to its antioxidant properties is also important for ATP generation and Vitamin E regeneration; a mixture of 10-100 mg epigallocatechin gallate (EGCG) and 25-150 mg polyphenols from green tea extract; 40-250 mg ellagic acid and punicalagin from pomegranate or raspberry extract, at ratios comparable to that found in the whole fruit, which have been shown to have protective effects on blood vessels as well as inhibiting stimulation of the pro-inflammatory protein interleukin-1 b (IL-b) which causes degradation and damage to joints (These six antioxidants prevent and eradicate reactive oxygen species and free radicals generated during strenuous exercise, thus preserving muscle integrity.); and (7) the ions Na+, Cl−, K+, Ca+2, Mg+ 2 , and Zn+ 2 , which are important for the muscle fiber contraction and relaxation cycle, for neuronal signal propagation, for repletion of such ions lost in excessive perspiration during exercise, for water absorption in the gastrointestinal tract, and for catalytic action by energy producing and antioxidant enzymes.

专利号:US-2006251608-A1
优先权日:2005-05-04
标题 :A Method of Treatment of Aging and Wrinkled Skin and a Kit Containing Compositions for Same
发明人：WACHSBERG RICHARD; WACHSBERG CHARLES
权利人:RWACHSBERG HOLDINGS INC
摘要:There is disclosed a method of treating aged and wrinkled skin and a kit containing compositions and instructions for such treatment. The method consists of a daily treatment regime, with two separate oral doses approximately 12 hours apart and application of a topical formulation. The oral formulations may be the same or different from each other, and each consist of one or more antioxidants, antioxidant co-promoters, anti-inflammatory, collagen synthesis promoters and optionally other substances. The topical formulation consists of an anti-wrinkle substance, such as a cream.

专利号:WO-0007607-A1
优先权日:1998-08-04
标 题:Nutrient and therapeutic compositions for the treatment of cancer
权利人:KOSBAB JOHN V
摘要:This invention relates to nutrient and therapeutic compositions for the treatment of cancer symptoms and conditions. Compositions of this invention contain a mixture of antioxidants, components that promote collagen maintenance and synthesis, components that regulate blood lipids, glucose and/or insulin, and lower homocysteine levels. Compositions also provide supplementation for nutrient (vitamin, mineral and cofactor) deficiencies to restore and maintain normal biochemical function. Cancer formulations, particularly those adapted for treatment of female cancers, can be combined with components that provide benefit in osteoporosis.

专利号:US-11820834-B2
优先权日:2018-07-10
标题 :Polymorphic forms of Cyclo (-His-Pro) and methods of use to treat kidney disease
发明人：OLMSTEAD KAY; PEARSON DAVID; MCPHERSON ELAINE
权利人:NOVMETAPHARMA CO LTD
摘要:The present disclosure relates to synthesis and characterization of novel polymorphic forms of Cyclo (-His-Pro) (“CHPâ€?).

专利号:US-2021060117-A1
优先权日:2019-08-15
标 题:Zinc activated thymulin and methods of preparation and administration
发明人：PRASAD ANAND S; VARGHESE ROY A; BIRD PHILIP C; CLAYTON CHARLES
权利人:CYTOLYF THERAPEUTICS LLC
摘要:Embodiments of the invention generally fall into the category of activated thymulin synthesis and applications thereof. Embodiments, delivered orally or parenterally, are used to treat malignancies and immune system dysfunctions by activating cytotoxic T cells, increasing the generation of T helper 1 cells and/or boosting the production of interleukin 2.

专利号:US-7427690-B2
优先权日:2004-06-05
标 题 :Multifunction “crown complexesâ€? from amino acids and peptides for skin and hair restoration
发明人：GUPTA SHYAM K
权利人:BIODERM RESEARCH
摘要:This invention relates to Schiff's bases derived from amino acids and hydroxyaryl alkyl ketones, or a plant extract containing the same, having general chemical structure in FIG. 1 for topical application. This invention also relates to certain metal complex of said Schiff's bases, which have a crown-like appearance in their three-dimensional chemical structure, as in FIG. 2 . The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase. These are further suitable for multifunctional topical methods for skin whitening, skin wrinkles reduction, skin antiaging, collagen synthesis, acne control, hair loss prevention, hair graying control, and facial oil control.