CAS: 14401-51-5; 4-Chlorobenzene-1-Carboximidamide Hydrochloride

相似化合物

24095-60-1 22978-61-6 50292-25-6

上下游产品

CAS号623-03-0 对氯苯腈 | CAS号40546-41-6 4-氯苯亚胺酸乙酯 | CAS号5033-28-3 4-氯-N-羟基苯羧酰亚胺 | CAS号623-03-0 对氯苯腈 | CAS号30894-94-1 2-chloro-4,6-bi... | CAS号1019-85-8 2-(4-氯苯基)苯并咪唑 | CAS号19922-07-7 5-氨基-3-(4-氯苯基)-... | CAS号7455-77-8 4(3H)-Quinazoli... | CAS号84660-25-3 2-(4-CHLORO-PHE... | CAS号95911-67-4 3-(4-chlorophen...

📜对氯苯甲腈置于氯化铵体系中,用 甲醇 用作溶剂,化学反应 72.0H,反应生成4-氯苯甲脒盐酸盐
参考文献:以碳化钙为炔烃源通过a3-偶联环化构建5-甲基-2,4-二芳基-1H-咪唑
标题:以碳化钙为炔烃源通过a3-偶联环化构建5-甲基-2,4-二芳基-1H-咪唑
摘要:咪唑衍生物是合成药物,荧光材料和配体的关键组成部分.尽管开发了许多策略,但 2,4,5-取代咪唑的可靠合成仍在大量研究中.在这项研究中,我们提出了一种合成 2,4,5-取代咪唑甲基的方案,使用 A3 偶联环化与碳化钙作为乙炔源,与脒和醛反应.该方法具有几个特点,包括使用固体炔烃源,易于获取的起始材料以及对 34 个示例的适用性.
Doi:10.1002/adsc.202300221

专利信息

专利号:US-12378203-B2
优先权日:2018-11-01
标题 :Imidazole compounds, process for the synthesis and uses thereof
发明人：VERMA MAHESH KUMAR; KOMIRISHETTY KASHINATH; GANJU PARUL; PRASAD SUDHANAND; RICHHARIA ANNIE; SHETE SANKET SANJAY
权利人:AHAMMUNE BIOSCIENCES PRIVATE LTD
摘要:The present invention relates to novel pharmaceutical agents and the process of preparation thereof. The present invention discloses compounds of general formula I, and the process of their preparation. The compounds of the invention are useful in the treatment and prevention of diseases related to cellular stress mediated immune deregulation and loss of homeostasis also including autoimmune diseases, cancers, metabolic, dermatological, cardiovascular and neurodegenerative diseases.

专利号:US-7501407-B2
优先权日:2001-12-20
标题 :Pyrimidine A2B selective antagonist compounds, their synthesis and use
发明人：CASTELHANO ARLINDO; MCKIBBEN BRYAN; STEINIG ARNO; COLLINGTON ERIC
权利人:OSI PHARM INC
摘要:The subject invention provides compounds having the structure: n nwherein R 1 is substituted or unsubstituted phenyl or a 5-6 membered heterocyclic or heteroaromatic ring containing from 1 to 5 heteroatoms; R 2 is hydrogen, or a substituted or unsubstituted alkyl, —C(O)-alkyl, —C(O)—O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety; R 3 is hydrogen, or a substituted or unsubstituted alkyl, —C(O)-alkyl, —C(O)—O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety, or R 2 and R 3 are joined to form a heterocyclic ring; wherein the dashed line represents a second bond which may be present or absent, and when present R 3 is oxygen; R 4 and R 5 are each independently substituted or unsubstituted alkyl, —C(O)-alkyl, —C(O)—O-alkyl, alkoxy, cycloalkyl, alkenyl, monocyclic or bicyclic aryl, heteroaryl or heterocyclic moiety, or R 4 NR 5 together form a substituted or unsubstituted monocyclic or bicyclic, heterocyclic or heteroaryl moiety containing from 1 to 6 heteroatoms;n R 12 is hydrogen, alkyl, halogen or cyano; and n is 0, 1, 2, 3 or 4, or an enantiomer, or a specific tautomer, or a pharmaceutically acceptable salt thereof and a method for treating a disease associated with the A 2b adenosine receptor by administering a therapeutically effective amount of the compounds of the invention.

专利号:CN-118086928-A
优先权日:2022-11-25
标 题:Method for electrochemical synthesis of pyrimidoindole derivative under mild condition

专利号:CN-109574942-A
优先权日:2018-12-11
标题 :Synthesis and Application of Novel Triazine Compounds as Light-Emitting Materials