CAS: 1227-61-8; N-(2-(Diethylamino)Ethyl)-2-(4-Methoxyphenoxy)Acetamide

该化合物是一种化学化合物,属于非类类类非类抗炎药物(NSAIDs),主要因其止痛和抗炎特性而得到承认,其特征为:甲酰胺具有抑制异丙菊酯合成的能力,该物质是人体炎症和疼痛的媒介;该化合物一般显示有机溶剂中具有中等溶解性,溶解力有限,可影响其生物利用率和药性皮肤病;甲基丙胺经常用于治疗疼痛和炎症的各种配方;其安全性特征和潜在副作用类似于其他非类甲胺药物,包括胃肠扰动和心血管风险;与任何制药剂一样,该物质的使用应当由保健专业人员指导,同时考虑到个别病人因素和潜在的药物相互作用;总体而言,甲酰苯胺是非甲胺在治疗环境内管理疼痛和发炎症的一个重要选择.

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CAS号42082-29-1 (4-甲氧基-苯氧基)-乙酰氯 | CAS号100-36-7 N,N-二乙基乙二胺 | CAS号51816-48-9 N-(2-hydroxyeth... | CAS号109-89-7 二乙胺 | CAS号18598-23-7 (4-甲氧基苯氧基)乙酸乙酯

合成工艺路线路线简述

    📜N-(2-Hydroxyethyl)-2-(4-Methoxyphenoxy)Acetamide置于氯化亚砜体系中,化学反应生成美非沙胺
    参考文献:Cassebaum,H.; Uhlig,K.,Journal Fur Praktische Chemie (Leipzig 1954),1973,Vol. 315,# 6,P. 1057-1066
    标题:Cassebaum,H.; Uhlig,K.,Journal Fur Praktische Chemie (Leipzig 1954),1973,Vol. 315,# 6,P. 1057-1066

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    专利信息


    专利号:US-2014315720-A1
    优先权日:2012-10-24
    标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
    发明人:FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
    权利人:CELANESE ACETATE LLC
    摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

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    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Zapletáiek M, Hübsch T, Zenatá L. The effect of mefexamide on some autonomic and psychological tests. Act Nerv Super (Praha). 1974 Aug;16(3):191-2. J Med Lyon. 1967 Apr 5;48(118):617-27. French.

    合成参考文献


    摘要:Chimica Therapeutica., 1(444), 1966
    摘要:S72 | NTUPHTW | Pharmaceutically Active Substances from National Taiwan University | DOI:10.5281/zenodo.3955664
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