CAS: 1222-05-5; Galaxolide

该化合物是一种合成口香糖化合物,由于其清洁,木质和混合气味的特征,广泛用于香味配方,它作为异丙醇混合物的混合物,在香水应用方面提供了更大的稳定性和多功能性.高纯度(> 80%)确保与多种香味成分的性能和兼容性. 伽拉索利德因其长期的传播和传递光滑,粉末底纸的能力而受到重视,使它成为香味,个人护理产品和家庭清洁剂的主食,其坚固的化学结构有助于出色的架状生命和氧化阻力,确保各种配方的可靠性能.

结构式图片

相似化合物

507442-49-1 786690-10-6 161297-43-4

欧盟法规

CLHactivity统一分类与标签欧盟化妆品法规附录三-限用物质清单REACH注册ECHA物质ECHA物质C&L通报REACH预注册废弃物危险特性清单

上下游产品

1,1,2,4,4,7-hexamethyl-1,2,3,4-tetrahydro-naphthalene acetyl chloride 2,3-Dimethyl-2-butene 1-methyl-4-isopropenylbenzene1,3,4,6,7,8-hexahydro-4,6,6,7,8,8-hexamethylcyclopenta[γ]-2-benzopyran-1-one

合成工艺路线路线简述

    2,3-二氢化-&beta置于三氯化铝 聚合甲醛体系中,用 二氯甲烷,水 用作溶剂,以95%的收率获得1,3,4,6,7,8-六氢-4,6,6,7,8,8-六甲基环五-γ-2-苯并吡喃
    参考文献:Process For Preparing Isochroman Compounds
    标题:Process For Preparing Isochroman Compounds
    摘要:高纯度异色苯酮化合物可以通过一种简单且经济的制备异色苯酮化合物的过程高产率地获得,该过程包括将浓度为40至70重量%的甲醛水溶液加入到由下述通式(II)所代表的芳基烷醇与弗里德尔-克拉夫特催化剂形成的复合物中,以使芳基烷醇环化:其中r.Sub.1和r.Sub.2分别代表氢原子,低碳基团或低碳氧基团,或者r.Sub.1和r.Sub.2分别与相邻碳原子相结合,R.Sub.1和r.Sub.2与r.Sub.1和r.Sub.2分别结合的碳原子一起形成苯环,萘环或可能具有1至6个低碳基团的c.Sub.5或c.Sub.6环烷烯,R.Sub.3代表氢原子或低碳基团.

    海关参考信息

    专利信息


    专利号:US-7501536-B2
    优先权日:2005-01-19
    标题 :Odorant compounds, synthesis method, and uses of said compounds
    发明人:JAUNKY PIOTR; MANE JEAN; SCHROEDER MARTIN
    权利人:MANE FILS V
    摘要:A compound of general formula (I) with or without the double bond illustrated by the dotted line. In formula (I), X is a CHO, CH2OH, CH2OC(O)R or CH(OR)2 group, and R represents a linear or branched C1-C5 alkyl or alkenyl chain. The synthesis method for the compound, and especially the 6,8-dimethyl-non-7-enal (1) prepared by the hydroformylation of the 5,7-dimethyl-octa-1,6-diene is also disclosed, as well as compositions containing the compounds of formula (I). Due to the odorant properties thereof, the compounds are highly useful in perfumery, especially for cosmetic products and household products.

    专利号:US-2009209449-A1
    优先权日:2008-02-20
    标题 :Novel woody odorants
    发明人:MAJEED MUHAMMED; RAJASEKHARAN PARTHASARATHY; THIRUVANATH VARIAM CHANDRAMOHA; RAJAMONY MAHESH
    权利人:MAJEED MUHAMMED; RAJASEKHARAN PARTHASARATHY; THIRUVANATH VARIAM CHANDRAMOHA; RAJAMONY MAHESH
    摘要:The present invention relates to novel substituted cyclohexyl monohydric alcohols possessing woody odor which are useful as fragrance materials. The invention also provides method for synthesis of the above compounds. The invention also provides fragrance compositions which utilize the compounds of the invention to impart woody aroma to such compositions. n The compounds of the invention have the general formula as under

    专利号:WO-8911536-A1
    优先权日:1988-05-27
    标题:Microbial biocatalyst for production of terpenic aldehydes
    发明人:DAVIS KAREN JOHANNA; BEST DAVID JOHN; BURFIELD ANTHONY GRAHAM; TAYLOR FRANK; TALBOT JANE STELLA
    权利人:NOVALAL LTD
    摘要:An active biocatalyst for converting alpha-pinene epoxide to terpenic aldehydes useful in perfumery, e.g. formula (I), is produced by growing a microorganism, preferably Pseudomonas fluorescens NCIB 40043, to late log phase in a medium containing carbohydrate (e.g. glucose) as the carbon source, and adding alpha-pinene. The resulting culture comprises active biocatalyst which is brought into contact with alpha-pinene epoxide for aldehyde synthesis.

    专利号:US-8349790-B2
    优先权日:2007-10-29
    标 题:Substituted octane(ene) nitriles, methods for the synthesis thereof and uses thereof in perfumery
    发明人:MANE JEAN; CLINET JEAN-CLAUDE
    权利人:MANE FILS V; MANE JEAN; CLINET JEAN-CLAUDE
    摘要:Compounds of general formula (I) below: in which R is a hydrogen atom, a methyl group, a CH2OH group, an ester group, preferably COOEt, or a methylene group, and in which not more than one of the four dashed lines represents a carbon-carbon double bond, and also their enantiomers and their diastereoisomers, a process for preparing them, and their use as an odorant agent in perfuming compositions.

    专利号:CA-2640585-A1
    优先权日:2003-02-05
    标题 :Synthesis of 2-butyl-3-(2'-(1-trityl-1h-tetrazol-5-yl)biphenyl-4-yl)-1,3-diazaspirol{4,4}-non-ene-4-one

    专利号:CN-117466262-A
    优先权日:2023-10-07
    标题 :Impurity removal method for phosphoric acid catalyst applied to synthesis of pentamethylindane
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    主要参考文献

    [参考文献]: Antti Knaapila, Et Al. A Genome-Wide Study On The Perception Of The Odorants Androstenone And Galaxolide. Chem Senses. 2012 Jul;37(6):541-52.
    [参考文献]: Denise Fernandes, Et Al. Metabolism Of The Polycyclic Musk Galaxolide And Its Interference With Endogenous And Xenobiotic Metabolizing Enzymes In The European Sea Bass (Dicentrarchus Labrax). Environ Pollut. 2013 Mar:174:214-21.
    [参考文献]: Emiel Rorije, Et Al. Read-Across Estimates Of Aquatic Toxicity For Selected Fragrances. Altern Lab Anim. 2013 Mar;41(1):77-90.
    [参考文献]: James Foltz, Et Al. Simultaneous Detection And Quantification Of Select Nitromusks, Antimicrobial Agent, And Antihistamine In Fish Of Grocery Stores By Gas Chromatography-Mass Spectrometry. Chemosphere. 2014 Jul:107:187-193.
    [参考文献]: Jie Yin, Et Al. The Occurrence Of Synthetic Musks In Human Breast Milk In Sichuan, China. Chemosphere. 2012 May;87(9):1018-23.

    合成参考文献


    摘要:Deutsche Lebensmittel - Rundschau., 94(268), 1998
    摘要:
    摘要:Full text:
    摘要:Fernandes D et al; Environ Pollut 174: 214-21 (2013)
    摘要:Liu N et al; Chemosphere 93(9): 1804-1810 (2013)
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