专利号:US-12037430-B2 优先权日:2018-10-17 标 题:Target substance polymer replica substrate, method for producing same, and method for producing substrate sensor 发明人:TAKEUCHI TOSHIFUMI; SUNAYAMA HIROBUMI; TAKANO ERI 权利人:UNIV KOBE NAT UNIV CORP; MURATA MANUFACTURING CO 摘要:The present invention provides a polymer replica of a target molecule, the polymer replica being capable of accurately inheriting surface information possessed by the target molecule in a molecular imprinting technique. A polymer replica of a target substance, the target substance having multiple types of binding groups including at least a binding group BG 1 and a binding group BG 2 on the surface, wherein: the polymer replica is configured from a second molecularly imprinted polymer having, as a template, a first molecularly imprinted polymer having the target substance as a template; the polymer replica has on the surface thereof at least a binding group bg 1 at a position corresponding to the position of binding group BG 1 and a binding group bg 2 at a position corresponding to the position of the binding group BG 2 on the surface of the target substance; and the polymer replica of the target substance can be used as a template during synthesis of a molecularly imprinted polymer having a specific recognition site for the target substance because the polymer replica accurately inherits the surface information possessed by the target molecule.
专利号:US-10995078-B2 优先权日:2013-03-13 标 题:Compounds and compositions for inhibition of FASN 发明人:BAIR KENNETH W; LANCIA JR DAVID R; LI HONGBIN; LOCH JAMES; LU WEI; MARTIN MATTHEW W; MILLAN DAVID S; SCHILLER SHAWN E R; TEBBE MARK J 权利人:FORMA THERAPEUTICS INC 摘要:The present invention relates to compounds and composition for inhibition of FASN, their synthesis, applications, and antidotes. An illustrative compound of the invention is shown below:
专利号:US-12227528-B2 优先权日:2017-11-09 标 题:Glucose-sensitive albumin-binding derivatives 发明人:KRUSE THOMAS; KOFOD-HANSEN MIKAEL; MUENZEL MARTIN WERNER BORCHSENIUS; THOEGERSEN HENNING; SAUERBERG PER; EWALD JAKOB; BEHRENS CARSTEN; HOEG-JENSEN THOMAS; BALSANEK VOJTECH; DROBNAKOVA ZUZANA; DROZ LADISLAV; HAVRANEK MIROSLAV; KOTEK VLADISLAV; STENGL MILAN; SNAJDR IVAN; DRUSANOVA HANA 权利人:NOVO NORDISK AS 摘要:This invention relates to glucose-sensitive albumin-binding diboron conjugates. More particularly the invention provides novel diboron compounds, and in particular diboronate or diboroxole compounds, useful as intermediate compounds for the synthesis of diboron conjugates.
专利号:SU-1766922-A1 优先权日:1986-12-17 标题:2-(4-carboxy-3-halogenphenyl)-5-alkyl-1,3,2-dioxaborinanes as semiproducts for synthesis of liquid-crystalline derivatives of halogen-pnenyl-5-alkyl-1,3,2-dioxaborinanes
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