CAS: 10472-24-9; Methyl 2-Cyclopentanonecarboxylate

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CAS号627-93-0 己二酸二甲酯 | CAS号17640-15-2 氰基甲酸甲酯 | CAS号120-92-3 环戊酮 | CAS号124-38-9 二氧化碳 | CAS号74-88-4 碘甲烷 | CAS号151930-48-2 methyl 1-hydrox... | CAS号292638-85-8 丙烯酸甲酯 | CAS号616-38-6 碳酸二甲酯 | CAS号7148-07-4 1-吡咯烷基-1-环戊烯 | CAS号10468-38-9 2-(3-bromopropy... | CAS号107986-99-2 methyl 1-(bromo... | CAS号10468-35-6 2,3,4,5,6,7-hex... | CAS号143391-47-3 Cyclopentanecar... | CAS号4819-67-4 2-戊基环戊酮 | CAS号2258-56-2 2-Cyclopentene-... | CAS号20461-31-8 2-methylidenecy... | CAS号22935-14-4 2-benzylhexaned... | CAS号3964-18-9 2,3-二甲基-2,3-二硝基丁烷

2-Diazocyclohexane-1,3-Dione 以 四氯化碳 用作溶剂,化学反应 0.17H,反应生成2-甲氧羰基环戊酮
参考文献:Direct Observation Of .Alpha.-Oxo Ketenes From The Photolysis Of .Alpha.-Diazo .Beta.-Diketones
标题:Direct Observation Of .Alpha.-Oxo Ketenes From The Photolysis Of .Alpha.-Diazo .Beta.-Diketones
摘要:Monitoring By Ir Spectroscopy Of The Broad-Band Irradiation Of The Symmetrically Substituted 2-Diazo-Cyclohexane-1,3-Dione (I 1),3-Diazopentane-2,4-Dione (19),And 4-Diazo-2,2,6,6-Tetramethylheptane-3,5-Dione (24) In Ar Matrices At 12 K Showed The Formation Of 2-Carbonylcyclopentanone (S-Z-12),Acetyl(Methyl)Ketene (S-E-20),And Tert-Butyl(Pivaloyl)Ketene (S-E-25),Respectively,In Less Than 10 Min. On Increasing The Photolysis Time To >3 H,The Alpha-Oxo Ketenes 12,20,And 25 Decarbonylated To The Corresponding Oxocarbenes Which Underwent Wolff Rearrangement To Carbonylcyclobutane (15),Dimethylketene (23),And Di-Tert-Butylketene (28),Respectively. The Reaction Of 2-Carbonylcyclopentanone (12) With Ch3Oh Was Monitored By Ir Spectroscopy. Thus,It Was Found That The Reaction Started At Ca. 100 K And Was Essentially Complete At 140 K,Involving The Initial Formation Of The Enol Form (9) Of Methyl 2-Oxocyclopentanecarboxylate.
Doi:10.1021/jo00044A019

专利信息

专利号:US-11149024-B2
优先权日:2017-03-31
标 题 :Synthesis of Mcl-1 inhibitor
发明人：STEWART CRAIG ROBERT; HARDY SIMON; STARK ANDREW; HIRD ALEXANDER; YE QING; ZHENG XIAOLAN; FERRAR CATI; KOEK JAN; HAZRA DEBASIS
权利人:ASTRAZENECA AB
摘要:Disclosed are intermediates and methods of synthesizing Compound 1.

专利号:US-5936127-A
优先权日:1997-01-13
标题:Asymmetric synthesis and catalysis with chiral heterocyclic compounds
发明人：ZHANG XUMU
权利人:PENN STATE RES FOUND
摘要:This invention relates to chiral heterocyclic compounds useful for asymmetric synthesis and catalysis. More particularly, the invention relates to chiral heterocyclic phosphine, sulfur, and nitrogen compounds for asymmetric synthesis and catalysis in the production of enantiomerically pure products.

专利号:US-8772301-B2
优先权日:2009-12-18
标题 :Compounds for treating disorders mediated by metabotropic glutamate receptor 5, and methods of use thereof
发明人：HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D
权利人:HARDY LARRY WENDELL; HEFFERNAN MICHELE L R; WU FRANK XINHE; SPEAR KERRY L; SARASWAT LAKSHMI D; SUNOVION PHARMACEUTICALS INC
摘要:Provided herein are compounds and methods of synthesis thereof. The compounds set forth herein are useful for the treatment, prevention, and/or management of various disorders, such as neurological disorders, neurodegenerative disorders, neuropsychiatric disorders, disorders of cognition, learning or memory, gastrointestinal disorders, lower urinary tract disorder, and cancer. Compounds set forth herein modulate the activity of metabotropic glutamate receptor 5 (mGluR5) in the central nervous system or the periphery. Pharmaceutical formulations containing the compounds and their methods of use are also provided herein.

专利号:WO-0214257-A2
优先权日:2000-08-11
标题 :SYNTHESIS OF Α,Ω-DIESTERS

专利号:US-2021122735-A1
优先权日:2017-03-31
标 题 :Synthesis of mcl-1 inhibitor

专利号:IL-269410-B
优先权日:2017-03-31
标 题 :Synthesis of mcl-1 inhibitor