CAS: 7432-28-2; (6S,7S,12Ar)-1,2,3,10,11,12-Hexamethoxy-6,7-Dimethyl-5,6,7,8-Tetrahydrodibenzo[a,C][8]Annulen-6-Ol

上下游产品

CAS号58546-54-6 戈米辛A | CAS号61281-38-7 五味子甲素

(+)-(R)-2-(2'-Oxopropyl)-4,5,6-Trimethoxy-2'-[1-Propenyl]-3',4',5'-Trimethoxy-1,1'-Biphenyl置于六甲基磷酰三胺,Samarium Diiodide,叔丁醇体系中,用 四氢呋喃 作为反应溶剂,化学反应 2.0H,反应生成 (+)-Isoschisandrin,五味子素
参考文献:利用碘化sa(II)促进的8-内基酮基-烯烃环化合成(+)-异五味子.
标题:利用碘化sa(II)促进的8-内基酮基-烯烃环化合成(+)-异五味子.
摘要:本文报道的(+)-异五味子素的13个步骤的合成具有碘化sa(II)促进的8-内基酮基-烯烃偶联,以组装存在于靶中的八元环以及所需的功能性和立体化学.在构建作为单一阻转异构体的(+)-异五味子素中,合成过程利用cbs-恶唑硼烷定律利用了七元内酯的动力学拆分.
DOI:10.1021/jo0347361

专利信息

专利号:IL-51381-A0
优先权日:1977-02-03
标 题 :Method for synthesis of schizandrin type lignans

专利号:US-6605305-B2
优先权日:2001-04-04
标 题 :Plant drug for treatment of liver disease
发明人：ZHAO XINXIAN
摘要:The present invention related to safe plant drug for treatment of liver disease, specifically, this invention proves a safe plant drug Schisandrin and its preparation. Schisandrin has the following pharmaceutical functions: increasing tumor suppresson genes express activity, decreasing activity of oncogenes, increasing immune function, increasing liver DNA synthesis, decreasing serum alamine aminotransferase activity, increasing glutathione level, increasing glutathione reductase activity, decreasing lipid peroxidation of liver, increasing hepatic microsomal monooxygenases activity, increasing ATP content in liver, increasing energy metabolism activity, decreasing density lipoprotein oxidation, protecting gastrointestinal function, increasing killer cell activity, increasing complement activity, decreasing induced liver cancer activity and decreasing grown of cancer cells.

专利号:CN-1303848-A
优先权日:1999-11-25
标题:A new method for the synthesis of β-bifendate

专利号:US-2009163573-A1
优先权日:2007-12-21
标 题:Compositions and methods for enhancing protein accretion in skeletal muscle
发明人：HEUER MARVIN A; CLEMENT KEN; MOLINO MICHELE; MACDOUGALL JOSEPH
权利人:MULTI FORMULATIONS LTD
摘要:A nutritional composition comprising at least an effective amount of geranylgeranylacetone or derivative of geranygeranylacetone and an effective amount of glutamine or derivative of glutamine, wherein the ingredients act substantially simultaneously to increase protein synthesis and inhibit protein degradation in skeletal muscle, via enhanced expression of heat shock proteins in cells, particularly heat shock protein 72. A method of same is also provided.

专利号:WO-2009079740-A1
优先权日:2007-12-21
标题:Compositions and methods for enhancing hypertrophy in skeletal muscle
发明人：HEUER MARVIN A; CLEMENT KEN; MOLINO MICHELE
权利人:MULTI FORMULATIONS LTD; MACDOUGALL JOSEPH; HEUER MARVIN A; CLEMENT KEN; MOLINO MICHELE
摘要:A nutritional composition comprising at least an effective amount of geranylgeranylacetone or derivative of geranygeranylacetone and an effective amount of glutamine or derivative of glutamine, wherein the ingredients act substantially simultaneously to increase protein synthesis and inhibit protein degradation in skeletal muscle, via enhanced expression of heat shock proteins in cells, particularly heat shock protein 72. A method of same is also provided.