CAS: 73522-17-5; (S)-Butane-1,2-Diol

相似化合物

40348-66-1 5077-67-8 3347-90-8

上下游产品

(2S)-2-hydroxybutanoic acid ethyloxirane benzaldehyde 1,2-dihydroxybutane (S)-(-)-2-hydroxybutyl tosylate (2S)-1-benzyloxy-2-butanol butyraldehyde

1,2-丁二醇 反应生成 (S)-1,2-丁二醇
参考文献:用贝克酵母介导的氧化制备手性 1,2-烷二醇
标题:用贝克酵母介导的氧化制备手性 1,2-烷二醇
摘要:(S)-1,2-链烷二醇与由面包酵母介导的相应 1-羟基-2-烷酮的生物还原产生的结构相反,是通过面包酵母介导的氧化制备的.在有氧条件下用面包酵母处理外消旋 1,2-烷二醇,然后去除通过 (R)-1,2-烷二醇的对映选择性氧化产生的相应 1-羟基-2-烷酮,得到 (S)-1,2-烷二醇.
DOI:10.1246/cl.1993.2123

专利信息

专利号:US-2025163076-A1
优先权日:2022-02-18
标 题 :Synthesis of bruton's tyrosine kinase inhibitors
发明人：TRAN NGOC DUC; XIOURAS CHRISTOS; CLEATOR EDWARD; MATON WILLIAM MARC; RAMMELOO THOMAS JOACHIM LANDEWALD; FERNANDES PHILIPPE; BONGARTZ JEAN-PIERRE A; CAO DUY CHI TRUNG; HORWITZ MATTHEW ALLAN; JUSSEAU XAVIER JEAN-MARIE; LEMAIRE SÉBASTIEN FRANCOIS-EMMANUEL; SCHWEITZER-CHAPUT BERTRAND
权利人:JANSSEN PHARMACEUTICA NV
摘要:The present disclosure is directed to methods of synthesizing a compound of Formula (I), where the R groups are defined herein, and to methods of synthesizing a compound of Formula (II). Some aspects of the present disclosure is directed to converting the compound of Formula (II) into its P form.

专利号:US-7220870-B2
优先权日:1995-03-14
标 题:Hydrolytic kinetic resolution of cyclic substrates
发明人：JACOBSEN ERIC N; TOKUNAGA MAKOTO; LARROW JAY F
权利人:HARVARD COLLEGE
摘要:The present invention relates to a process for stereoselective or regioselective chemical synthesis which generally comprises reacting a nucleophile and a chiral or prochiral cyclic substrate in the presence of a non-racemic, chiral catalyst to produce a stereoisomerically- and/or regioisomerically-enriched product. The present invention also relates to hydrolytic kinetic resolutions of racemic and diastereomeric mixtures of epoxides.

专利号:US-8129544-B2
优先权日:2002-10-15
标题:1-substituted-4-nitroimidazole compound and method for preparing the same
发明人：GOTO FUMITAKA; TAKEMURA NORIAKI; OTANI TADAAKI; HASEGAWA TAKESHI; TSUBOUCHI HIDETSUGU; UTSUMI NAOTO; FUJITA SHIGEKAZU; KURODA HIDEAKI; SHITSUTA TAKUYA; SASAKI HIROFUMI
权利人:GOTO FUMITAKA; TAKEMURA NORIAKI; OTANI TADAAKI; HASEGAWA TAKESHI; TSUBOUCHI HIDETSUGU; UTSUMI NAOTO; FUJITA SHIGEKAZU; KURODA HIDEAKI; SHITSUTA TAKUYA; SASAKI HIROFUMI; OTSUKA PHARMA CO LTD
摘要:The present invention relates to a 1-substituted-4-nitroimidazole compound represented by the general formula (1) or a salt thereof, n n(wherein R is a hydrogen atom, a lower alkoxy group-substituted lower alkyl group, a phenyl-lower alkoxy group-substituted lower alkyl group, a cyano-substituted lower alkyl group, a phenyl-lower alkyl group which may have lower alkoxy groups as the substituents in the phenyl ring or a group of the formula —CH 2 R A ; X is a halogen atom or a group of the formula —S(O)n-R 1 ) and method for preparing the same. The compound of the formula (1) is a useful compound as an intermediate for synthesis of various pharmaceutical and agricultural chemicals, particularly, as intermediates for antitubercular agents.

专利号:WO-2023156599-A1
优先权日:2022-02-18
标 题 :Synthesis of bruton's tyrosine kinase inhibitors

专利号:EP-4479405-A1
优先权日:2022-02-18
标 题:Synthesis of bruton's tyrosine kinase inhibitors

专利号:CN-118715228-A
优先权日:2022-02-18
标题 :Synthesis of bruton's tyrosine kinase inhibitor