CAS: 610-66-2; 2-(2-Nitrophenyl)Acetonitrile

上下游产品

2-hydroxyimino-3-(2-nitro-phenyl)-propionic acid nitro-phenyl-acetic acid amide acetic anhydride phenylacetonitrile indole 2-(2-nitrophenyl)acetic acid 2-aminophenylacetonitrile 2,3-Bis(2-nitrophenyl)propanenitrile

2-硝基苯乙酸置于氨体系中,化学反应 1.5H,反应生成 邻硝基苯乙腈
参考文献:腈及其相应胺的制造方法
标题:腈及其相应胺的制造方法
摘要:本发明涉及一种腈的制造方法,与现有技术相比,具有氨源用量显著降低,环境压力小,能耗低,生产成本低,腈产物的纯度和收率高等特点,并且能够获得结构更为复杂的腈.本发明还涉及由该腈制造相应胺的方法.

专利信息

专利号:US-8445734-B2
优先权日:2003-02-21
标 题:Photolabile protective groups for improved processes to prepare oligonucleotide arrays
发明人：BUEHLER SIGRID; OTT MARKUS; PFLEIDERER WOLFGANG
权利人:BUEHLER SIGRID; OTT MARKUS; PFLEIDERER WOLFGANG; NIGU CHEMIE GMBH
摘要:The present invention discloses novel and improved nucleosidic and nucleotidic compounds that are useful in the light-directed synthesis of oligonucleotides, as well as, methods and reagents for their preparation. These compounds are characterized by novel photolabile protective groups that are attached to either the 5′- or the 3′-hydroxyl group of a nucleoside moiety. The photolabile protective group is comprised of a 2-(2-nitrophenyl)-ethyoxycarbonyl skeleton with at least one substituent on the aromatic ring that is either an aryl, an aroyl, a heteroaryl or an alkoxycarbonyl group. The present invention includes the use of the aforementioned compounds in light-directed oligonucleotide synthesis, the respective assembly of nucleic acid microarrays and their application.

专利号:US-4476315-A
优先权日:1982-04-30
标 题:Nucleophilic substitution process
发明人：STAHLY G PATRICK; STAHLY BARBARA C
权利人:ETHYL CORP
摘要:Nitroarylacetic acid esters are prepared by reacting a nitroaromatic compound which is devoid of halogen on the aromatic ring carrying a nitro group with an alpha,alpha-disubstituted acetic acid ester in an inert solvent and in the presence of a base so that the ester undergoes a nucleophilic substitution on an unsubstituted ring carbon of the nitroaromatic compound during which an alpha-substituent functions as a leaving group. Nitrobenzene acetic acids and their esters are useful intermediates for the synthesis of pharmaceuticals.

专利号:US-4499026-A
优先权日:1982-08-25
标题 :Nucleophilic substitution process
发明人：STAHLY BARBARA C; STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Nitroarylacetonitriles are prepared by reacting a nitroaromatic compound which is devoid of halogen on the aromatic ring carrying a nitro group with an alpha,alpha-disubstituted acetonitrile in an inert solvent and in the presence of a base so that the nitrile undergoes a nucleophilic substitution on an unsubstituted ring carbon of the nitroaromatic compound during which an alpha-substituent functions as a leaving group. Nitrobenzene acetic acids and their nitriles are useful intermediates for the synthesis of pharmaceuticals.

专利号:CN-1462738-A
优先权日:2003-06-10
标题 :Synthesis of o-nitrophenylacetic acid and its phase transfer catalysis

专利号:US-4502998-A
优先权日:1982-08-25
标题 :Nucleophilic substitution process
发明人：STAHLY BARBARA C; STAHLY G PATRICK
权利人:ETHYL CORP
摘要:Nitrophenoxy- or phenylthiobenzeneacetonitriles are prepared by reacting a nitrophenoxy- or nitrophenylthiobenzene with an alpha,alpha-dinitrosubstituted acetonitrile in an inert solvent and in the presence of a base. The products are useful as intermediates for the synthesis of pharmaceuticals, such as fenoprofen.

专利号:CN-1228307-C
优先权日:2003-06-10
标题 :Phase Transfer Catalytic Synthesis of o-Nitrophenylacetic Acid