CAS: 56578-37-1; (E)-3-Chlorocinnamaldehyde

该化合物是一种有机化合物,其特点是不饱和的甲醚结构,其特点是一种蛋白质骨,其第三种位置为一种替代基质,其替代成分为氯苯,这有利于其独特的化学特性.氯化芳香环的存在会增强其在有机合成和药用化学中的回活动性和潜在应用.该化合物通常呈现黄色至褐色,有独特的气味,即甲状腺的特征.该化合物在有机溶剂中可溶解,并可能参与各种化学反应,包括核糖基化合物添加和聚合.该氯苯基组可影响该化合物的生物活动,使其对制药或农业化学的开发具有兴趣.和许多甲状腺素一样,它可能构成某些健康风险,需要小心处理和储存.

结构式图片

上下游产品

CAS号1504-67-2 3-chlor°Cinnamy... | CAS号625-99-0 3-氯碘苯 | CAS号75-07-0 乙醛 | CAS号587-04-2 3-氯苯甲醛

合成工艺路线路线简述

    📜1-(间氯苯基)乙酸烯丙酯置于双(乙腈)氯化钯(II),Sodium Methylate Manganese(Iv) Oxide体系中,用 甲醇,Petroleum Ether,苯 作为反应溶剂,化学反应 5.0H,反应生成 3-氯肉桂醛
    参考文献:Crilley,Martine M. L.; Golding,Bernard T.; Pierpoint,Colin,Journal Of The Chemical Society. Perkin Transactions I,1988,P. 2061-2068
    标题:Crilley,Martine M. L.; Golding,Bernard T.; Pierpoint,Colin,Journal Of The Chemical Society. Perkin Transactions I,1988,P. 2061-2068

    海关参考信息

    专利信息


    专利号:US-8558012-B2
    优先权日:2009-03-02
    标 题:2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative, production method thereof, and production method of monofluoromethyl group-containing compound using the same
    发明人:SHIBATA NORIO
    权利人:SHIBATA NORIO; NAGOYA INST TECHNOLOGY; TOSOH P TECH INC
    摘要:A 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative as a monofluoromethyl group introduction agent that is effective as an intermediate in pharmaceutical and agrochemical synthesis, a production method thereof, and a production method of a monofluoromethyl group-containing compound using this 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative are provided. The 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative represented by the following general formula (1) (wherein R 1 , R 2 , R 3 , and R 4 each independently represent a hydrogen atom, a straight-chain or branched alkyl group having 1 to 4 carbon atoms, a straight-chain or branched alkyloxy group having 1 to 4 carbon atoms, a halogen atom, a nitro group, or a cyano group), the production method thereof, and various monofluoromethyl group-containing compounds are manufactured using this 2-fluoro-1,3-benzodithiol 1,1,3,3-tetraoxide derivative as a monofluoromethylating agent.

    专利号:US-10829464-B2
    优先权日:2016-11-23
    标题 :Benzoheterocyclic alkylamine compounds and use thereof
    发明人:LI JIAN; LAN LEFU; LI BAOLI; CHEN FEIFEI; NI SHUAISHUAI; LIU YIFU; WEI HANWEN; MAO FEI; ZHU JIN
    权利人:UNIV EAST CHINA SCIENCE & TECH; SHANGHAI INST MATERIA MEDICA CAS
    摘要:Disclosed are benzoheterocyclic alkylamine compounds, or a pharmaceutically acceptable salt thereof, or a stereoisomer thereof, and a preparation method thereof, and use of the same in the manufacture of an antibacterial drug as an inhibitor of staphyloxanthin synthesis in Staphylococcus aureus .

    专利号:CN-117466815-A
    优先权日:2023-07-27
    标题 :A kind of synthesis method of azathrone compounds

    专利号:CN-104059083-B
    优先权日:2014-05-27
    标 题 :Asymmetric synthesis method of chiral bicyclocaprolactam compounds

    专利号:CN-104059083-A
    优先权日:2014-05-27
    标题 :Asymmetric synthesis method of chiral bicyclocaprolactam compounds

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:González-Bello, C., Science of Synthesis Knowledge Updates, (2018) 3, 441.
    摘要:Franciò, G.; Leitner, W.; Alsters, P. L., Science of Synthesis: Stereoselective Synthesis, (2011) 1, 500.
    摘要:Córdova, A.; Zhang, K.; Deiana, L., Science of Synthesis, (2022) , 127.
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