CAS: 2346-00-1; 2-Methyl-4,5-Dihydrothiazole

相似化合物

29926-41-8 56367-27-2 504-79-0

上下游产品

CAS号24050-16-6 2-甲基噻唑烷 | CAS号142-26-7 N-乙酰乙醇胺 | CAS号75-36-5 乙酰氯 | CAS号1190-73-4 N-乙酰基半胱胺 | CAS号75-07-0 乙醛 | CAS号60-23-1 β-巯基乙胺 | CAS号2576-47-8 2-溴乙胺氢溴酸盐 | CAS号62-55-5 硫代乙酰胺 | CAS号108-24-7 乙酸酐 | CAS号75-05-8 乙腈 | CAS号3581-87-1 2-甲基噻唑 | CAS号26934-29-2 2,3-DIMETHYLTHI... | CAS号60-23-1 β-巯基乙胺 | CAS号13146-73-1 2H-Thiazolo[3,2... | CAS号1190-73-4 N-乙酰基半胱胺 | CAS号6197-31-5 s-(2-氨乙基)硫代乙酸 | CAS号107-35-7 牛磺酸 | CAS号111709-77-4 2-(4-methylhept... | CAS号7081-80-3 2-[(3-Phenylpro... | CAS号75606-47-2 2-(1,1-Dimethyl...

📜N-乙酰乙醇胺置于tetraphosphorus Decasulfide体系中,化学反应生成2-甲基-2-噻唑啉
参考文献:酰基和硫代酰基异氰酸酯的研究-Xi:苯甲酰基和硫代苯甲酰基异氰酸酯与2-噻唑啉和2-恶唑啉的反应
标题:酰基和硫代酰基异氰酸酯的研究-Xi:苯甲酰基和硫代苯甲酰基异氰酸酯与2-噻唑啉和2-恶唑啉的反应
摘要:异氰酸硫代苯甲酰基酯加到2-噻唑啉及其2-甲基衍生物中,得到相应的(4 + 2)环加合物.异氰酸苯甲酰基酯与2-甲基噻唑啉的反应得到2,3-二氢-5-苯基-8-苯甲酰基氨基甲酰基噻唑并[3,2-C]嘧啶-7-One.异氰酸苯甲酰基酯与2-甲基-2-噻唑啉和-2-恶唑啉在90°下反应形成相应的8-硫苯甲酰基氨基甲酰基噻唑并-和-恶唑并[3,2-C]嘧啶-7-酮,而苯甲酰基异氰酸酯与2-甲基恶唑啉提供2∶1的加合物,其与乙酸产生相应的恶唑并[3,2-C]嘧啶.异氰酸苯甲酰酯与2-乙基-2-噻唑啉反应生成2,3-二氢-6-苯甲酰基-8-甲基噻唑并[3,2-C]嘧啶-5,7-二酮和2,3-二氢-5-苯基-8-甲基噻唑并[3,2-C]嘧啶-7-一;描述了它们的酸和碱水解.通过两种异氰酸酯对2-烷基-2-噻唑啉和-2-恶唑啉的互变异构烯胺的β-碳的攻击.
Doi:10.1016/0040-4020(72)88081-5

专利信息

专利号:US-10189803-B2
优先权日:2008-02-22
标题 :Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
发明人：CHONG HYUN-SOON
权利人:CHONG HYUN SOON; ILLINOIS INSTITUTE OF TECH
摘要:Stereoselective and regioselective synthesis of compounds via nucleophilic ring opening reactions of aziridinium ions for use in stereoselective and regioselective synthesis of therapeutic and diagnostic compounds.

专利号:US-2006014987-A1
优先权日:2003-07-07
标 题:Synthesis of beta-elemene, intermediates thereto, analogues and uses thereof
发明人：HUANG LAN
权利人:HUANG LAN
摘要:The present invention provides convergent processes for preparing beta-elemene, and analogues thereof. Also provided are analogues related to beta-elemene and intermediates useful for preparing the same. The present invention further provides novel compositions based on analogues of beta-elemene and methods for the treatment of cancer, such as brain tumor, lung cancer, colorectal cancer, gastric intestional cancer, and stomach cancer.

专利号:US-2005043376-A1
优先权日:1996-12-03
标题:Synthesis of epothilones, intermediates thereto, analogues and uses thereof
发明人：DANISHEFSKY SAMUEL J; BERTINATO PETER; SU DAI-SHI; MENG DONGFANG; CHOU TING-CHAO; KAMENECKA TED; SORENSEN ERIK J; BALOG AARON; SAVIN KENNETH A
摘要:The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.

专利号:US-3943142-A
优先权日:1969-01-24
标 题:Dye intermediates and their preparation and use in the synthesis of methine dyes
发明人：OWEN JOHN R
权利人:EASTMAN KODAK CO
摘要:Compositions of matter are provided comprising a stable, non-vaporous monomeric methylene base selected from a 2-methylenethiazoline; a 2-methylenebenzothiazoline; a 2-methylenenaphthothiazoline; a 2-methylenebenzoselenazoline; and a 2-methylenenaphthoselenazoline. The compositions of the invention are prepared by reacting the parent 2-methyl quaternary salt with a non-hydroxylic base which removes a proton of the heterocyclic salt together with a proton acceptor which inhibits build-up of the hydro salt of the non-hydroxylic base, the reaction being conducted under anhydrous conditions in a non-hydroxylic liquid in which the heterocyclic quaternary salt is sufficiently insoluble to inhibit dimer formation. The compositions of the invention are employed in the preparation of methine dyes.

专利号:US-11459345-B2
优先权日:2020-08-14
标题:Method for the synthesis of asymmetric polysulfides
发明人：CANTWELL KELSEY ELIZABETH; KULIG JOSEPH JOHN
权利人:GOODYEAR TIRE & RUBBER
摘要:The present invention is directed to a method of making an asymmetric polysulfide, comprising the step of simultaneously reacting an olefinically unsaturated compound, elemental sulfur, and a thiol in the presence of a catalytic amount of a base to produce the asymmetric polysulfide.

专利号:US-RE41990-E
优先权日:1996-12-03
标 题 :Synthesis of epothilones, intermediates thereto, analogues and uses thereof
发明人：DANISHEFSKY SAMUEL J; BERTINATO PETER; SU DAI-SHI; MENG DONGFANG; CHOU TING-CHAO; KAMENECKA TED; SORENSEN ERIK J; BALOG AARON; SAVIN KENNETH A
权利人:SLOAN KETTERING INST CANCER
摘要:The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.