CAS: 1811-28-5; Acridine-3,6-Diamine Hemisulfate
该化合物是一个化学化合物,其结构特征包括3和6个位置上两个氨基组的腹膜脊柱,一般是硫酸盐盐,表明它是硫酸盐离子的稳定的离子化合物;已知由于氨基生物群的再活动,它有可能在各个领域应用,包括药物和染料制造;能够参与进一步化学改造的氨基生物群(2:1),因此,丙烯酸盐的存在有助于其独特的光学和电子特性,使其在有机电子学和光学应用中具有兴趣;此外,该化合物可能展示生物活动,值得对潜在的治疗用途进行调查;安全数据应同任何化学物质一起加以审查,以了解其处理,毒性和环境影响;
- 英文名称Acridine-3,6-Diamine Hemisulfate
- 中文名称硫酸原黄素
- IUPAC名称(6-aminoacridin-3-yl)azanium;sulfate
- 其它别名3,6-acridinediamine,sulfate(21); 3,6-diamino-acridinsulfate(21); PROFLAVINE SULFATE; PROFLAVINE HEMISULFATE; PROFLAVINE HEMISULFATE SALT; PROFLAVINE HEMISULPHATE; 3,6-DIAMINOACRIDINE SULFATE; 3,6-DIAMINOACRIDINIUM MONOHYDROGEN SULFATE
- CAS编号1811-28-5
- MFCD编号:MFCD00149650
- EINECS号:217-320-3
- FDA UNII编号:27V8M747VB
- 分子式:C13H13N3O4S分子量:307.33
- 产品CID: 934124
- 同类组份化合物CAS92-62-6 (free base)1811-28-5 (hemisulfate)
- 产品分类有机原料→生命科学→生化试剂→荧光探针,标记，染色
物理性质
MSDS等安全信息
- GHS象形图
- GHS符号GHS07;
注释: Exclamation mark - 危险类别急性毒性 类别4(经口)
特定目标器官毒性 - 单次接触 类别3
皮肤腐蚀/刺激 类别2
严重眼刺激 类别2 - 警示词Warning(警告)
- 危险描述H302 |吞咽有害.
H335 |可能引起呼吸道刺激.
H315 |造成皮肤刺激.
H319 |造成严重眼刺激. - 防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
- UN编号NONH for all modes of transport
- 危险品标志Xi
- 安全声明26-36
- 危险类别码36/37/38
- WGK Germany3
欧盟法规
ECHA物质C&L通报REACH预注册上下游产品
acriflavineN,N'-Dibenzhydrylidene-acridine-3,6-diamine N3,N6-bis-(4-methoxy-benzyliden)-acridine-3,6-diyldiamineN3,N6-bis-(4-methoxy-benzyliden)-acridine-3,6-diyldiamine合成工艺路线路线简述
海关参考信息
- 2933310010-吡啶
2939800000-其他生物碱 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:US-2005202459-A1
优先权日:2003-09-23
标 题 :Intercalation-mediated synthesis of polymers
专利号:US-7368560-B2
优先权日:2003-09-23
标题:Intercalation-mediated synthesis of polymers
发明人：HUD NICHOLAS V
权利人:GEORGIA TECH RES INST
摘要:Methods and compositions for synthesizing biopolymers using an intercalator are provided. Aspects provide compositions and methods for synthesizing biopolymers with non-natural backbones or non-natural biopolymer subunits using natural biopolymer templates. Other aspects provide compositions and methods for synthesizing biopolymers using a template with a non-natural backbone on non-natural biopolymer subunits.
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品牌试剂参考报价(招募中)
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主要参考文献
1: Sasikala WD, Mukherjee A. Structure and dynamics of proflavine association around DNA. Phys Chem Chem Phys. 2016 Mar 31. [Epub ahead of print] doi: 10.1177/1078155214546564. Epub 2014 Aug 10. doi: 10.1371/journal.pone.0125598. eCollection 2015.
4: Kumar V, Sengupta A, Gavvala K, Koninti RK, Hazra P. Spectroscopic and thermodynamic insights into the interaction between proflavine and human telomeric G-quadruplex DNA. J Phys Chem B. 2014 Sep 25;118(38):11090-9. doi: 10.1021/jp506267b. Epub 2014 Sep 11. doi: 10.1366/13-07205. doi: 10.1016/j.bmc.2013.08.007. Epub 2013 Aug 13. doi: 10.1002/bio.2437. Epub 2012 Oct 18. doi: 10.1002/cphc.201300045. Epub 2013 May 14. doi: 10.1039/c3cp50501d. doi: 10.1016/j.vaccine.2013.03.004. Epub 2013 Mar 13. doi: 10.1021/ic302456q. Epub 2013 Jan 4. doi: 10.1021/jp307911r. Epub 2012 Oct 1. doi: 10.1002/cbic.201200115. Epub 2012 May 3. doi: 10.1039/c2mb05430b. Epub 2012 Jan 18. doi: 10.1021/jp207495r. Epub 2011 Dec 23. doi: 10.1007/s10895-011-0873-8. Epub 2011 Mar 30. doi: 10.1016/j.jinorgbio.2010.12.010. Epub 2010 Dec 31. doi: 10.1016/j.bmcl.2011.03.010. Epub 2011 Mar 6. doi: 10.1016/j.jinorgbio.2010.07.010. Epub 2010 Jul 23.
20: García B, Leal JM, Ruiz R, Biver T, Secco F, Venturini M. Change of the binding mode of the DNA/proflavine system induced by ethanol. J Phys Chem B. 2010 Jul 1;114(25):8555-64. doi: 10.1021/jp102801z.
合成参考文献
摘要:Quarterly Journal of Pharmacy & Pharmacology., 10(649), 1937
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