专利号:US-8269001-B2 优先权日:2005-10-05 标题 :Process for the synthesis of HMG-CoA reductase inhibitors 发明人:CASAR ZDENKO 权利人:CASAR ZDENKO; LEK PHARMACEUTICALS 摘要:A novel synthesis of statins uses Wittig reaction of a heterocyclic core of statin with a lactonized side chain already possessing needed stereochemistry. Any separation of diastereoisomers is performed early in the course of synthesis.
专利号:US-2024279264-A1 优先权日:2021-10-22 标题:Catalytic polymerization and depolymerization of 1,6-anhydrosugars 发明人:NIU JIA; WU LIANQIAN 权利人:THE TRUSTEES OF BOSTON COLLEGE 摘要:Methods for controlled synthesis and chemical recycling of stereoregular polysaccharides via polymerization of biomass-derived anhydrosugars are provided. The anhydrosugars react with an initiator in the presence of a synergy of a catalyst and the initiator providing the polysaccharides with high chain end fidelity and an excellent molecular weight distribution in a controlled manner, which allows for the preparation of polymeric systems with well-defined architectures. The polysaccharides obtained by such methods can be substantially converted to the start monomers in the present of a catalyst and can be used for biomedicine.
专利号:US-2008300406-A1 优先权日:2005-10-05 标 题 :Process for the Synthesis of Hmg-Coa Reductase Inhibitors
专利号:EP-1937696-B1 优先权日:2005-10-05 标题:PROCESS FOR THE SYNTHESIS OF HMG-CoA REDUCTASE INHIBITORS
专利号:EP-2341054-B1 优先权日:2005-10-05 标题:Process for the synthesis of HMG-CoA reductase inhibitors
专利号:EP-2341054-A1 优先权日:2005-10-05 标题:Process for the synthesis of HMG-CoA reductase inhibitors