CAS: 15199-43-6; Dimethyl-D6 Sulfate

该化合物是一种化学化合物,其特点是存在一种分离液,一种稳定的氢同位素,取代了甲醇中的氢原子.这种替代结果形成一种化合物,这种化合物在各种科学应用中非常有用,特别是在NMR光谱学和涉及同位素标签的研究中.硫酸盐组(-SO4)表明,该化合物是一个硫酸酯酯,可影响其溶解性和再活动.Methan-d3-ol, 1,1欧元硫酸盐在室温时通常是无色液体,由于乙醇和硫酸盐成分的极性,在水中溶解.其独特的同位素构成使研究人员能够追踪生物系统中的代谢途径和相互作用.在处理和储存准则方面,应参考安全数据表,如任何化学物质一样,以确保采取适当的安全措施.

英文名称Dimethyl-D6 Sulfate
中文名称氘代硫酸二甲酯
IUPAC名称bis(trideuteriomethyl) sulfate
其它别名(Methylsulfate)-d6 (6CI); Methan-d3-ol, sulfate (21) (9CI); Sulfuric acid,di(methyl-d3) ester (8CI); Dimethyl-d6 sulfate
CAS编号15199-43-6
EINECS号:239-257-0
分子式:C2H6O4S分子量:132.086
产品CID: 743926
产品分类化学试剂 → 氘代试剂

相似结构搜索
InChIKey: VAYGXNSJCAHWJZ-WFGJKAKNSA-N
1S/C2H6O4S/c1-5-7(3,4)6-2/h1-2H3/i1D3,2D3
计算化学: 氢键受体数4.0氢键供体数*可旋转键数2.0

MSDS等安全信息

GHS象形图
GHS符号GHS08 & GHS06 & GHS05;
注释: Health hazard & Skull and crossbones & Corrosion
危险类别致癌性类别1B
致突变性类别2
急性毒性类别2(吸入)
急性毒性类别3(经口)
皮肤腐蚀类别1B
皮肤致敏类别1
致癌性类别1A
严重眼损伤类别1
警示词Danger(危险)
危险描述H350 |可能致癌.
H341 |怀疑导致遗传缺陷.
H330 |吸入致命.
H301 |吞咽会中毒.
H314 |造成严重皮肤灼伤和眼损伤.
H317 |可能引起皮肤过敏反应.
H318 |造成严重眼损伤.
防范说明P201,P260,P280,P284,P301+P310,P305+P351+P338
UN编号UN 1595 6
危险品标志T+: Very toxic;
安全声明53-45
危险类别码R45
WGK Germany3

欧盟法规

ECHA物质C&L通报REACH预注册

上下游产品

合成工艺路线路线简述

📜甲醇-D3置于chlorosulphuric Acid体系中,化学反应生成氘代硫酸二甲酯
参考文献:有机氘化合物:Xxi.氘代偶氮二甲烷的合成
标题:有机氘化合物:Xxi.氘代偶氮二甲烷的合成
摘要:氘代偶氮二甲烷是由硫酸二甲酯和肼以常规方式合成的.
Doi:10.1139/v59-001

海关参考信息

2905110000-甲醇
2904100000-仅含磺基的衍生物及其盐和乙酯
💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
详情请参考：📖 海关编码查询和海关进出口税则

专利信息

专利号:US-9309165-B2
优先权日:2012-12-19
标题 :6-chloro-3-(phenyl-d5)-inden-1-one and use thereof
发明人：JACOBSEN MIKKEL FOG; BRANDES SEBASTIAN
权利人:LUNDBECK & CO AS H
摘要:The present invention discloses the compound 6-chloro-3-(phenyl-d 5 )-inden-1-one (I) and routes of synthesis to obtain (I). In a further aspect the present invention discloses the use of (I) for the synthesis of (S)-6-chloro-3-(phenyl-d 5 )-indan-1-one.

专利号:US-2010137244-A1
优先权日:2006-07-13
标题 :Preparation and utility of hmg-coa reductase inhibitors
发明人：GANT THOMAS G; SARSHAR SEPEHR
权利人:AUSPEX PHARMACEUTICALS INC
摘要:Chemical syntheses and medical uses of novel modulators of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase and diastereomeric mixtures of isomers, individual diastereomers, pharmaceutically acceptable salts, solvates, or prodrugs thereof, the chemical synthesis thereof, and the medical use of such compounds for the treatment and/or management of hypercholesterolemia, dyslipidemia, coronary artery disease, atherosclerosis, metabolic syndrome, a hyperproliferative disease such as colorectal cancer, prostate cancer, and melanoma, a neurodegenerative disease such as cerebral ischemia, Alzheimer's disease, and Parkinson's disease are described.

专利号:EP-3478664-B1
优先权日:2016-07-04
标题 :Methods for the synthesis of deuterated dextromethorphan

专利号:US-2019241525-A1
优先权日:2016-07-04
标题:Methods for the synthesis of deuterated dextromethorphan

专利号:US-10865187-B2
优先权日:2016-07-04
标题 :Methods for the synthesis of deuterated dextromethorphan

专利号:EP-3478664-A1
优先权日:2016-07-04
标题:Methods for the synthesis of deuterated dextromethorphan