CAS: 138923-03-2; (1S,4R)-Methyl 4-Aminocyclopent-2-Enecarboxylate
该化合物是一种具有氨基和酯功能组的手性环球开源衍生物,其立体化学定义结构(1S,4R)使其成为非对称合成中有价值的中间体,特别是用于制药和生物活性化合物的制作.氨基组的存在允许进一步功能化,而酯细胞在衍生或水解方面具有多功能性.该化合物的硬性环球开源骨架有助于合成应用的一致控制.其高纯度和定义明确的立体化学确保研究和工业流程的再生性,使其成为医药化学和催化剂发展的首选.
- 英文名称(1S,4R)-Methyl 4-Aminocyclopent-2-Enecarboxylate
- 中文名称(1S,4R)-4-氨基环戊-2-烯-1-甲酸甲酯
- IUPAC名称methyl (1S,4R)-4-aminocyclopent-2-ene-1-carboxylate
- 其它别名(-)(1S,4R)4-氨基-环戊-2-烯基甲酸甲酯; 2-Cyclopentene-1-Carboxylicacid,4-Amino-,Methylester,(1S,4R)-(9Ci)
- CAS编号138923-03-2
- MFCD编号:MFCD16293378
- 分子式:C7H11NO2分子量:141.17
- 产品CID: 601902
- 产品分类有机原料→分子砌块→脂肪环类化合物→环戊烷类化合物
相似化合物
229613-83-6 168683-02-1 77745-25-6物理性质
MSDS等安全信息
上下游产品
methanol (-)-(1S, 4R)-4-amino-2-cyclopentene-1-carboxylic acid (-)-2-azabicyclo[2.2.1]hept-5-en-3-one 2-azabicyclo[2.2.1.]hept-5-en-3-one (1S,4R)-(-)-methyl-[[(1,1-dimethylethoxy)carbonyl]amino]cyclopent-2-ene-1-carboxylate (+)-methyl (3aR,4R,6S,6aS)-4-[(tert-butoxycarbonyl)-amino]-3-(1-ethylpropyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]isoxazole-6-carboxylate (1S,3R)-3-Benzyloxymethyl-cyclopentylamine合成工艺路线路线简述
- 合成目标产物 Methyl (1S,4R)-4-Amino-2-Cyclopentene-1-Carboxylate 主要起始原料 Methanol And 2-Azabicyclo[2.2.1]Hept-5-En-3-One
- (文献来源)合成步骤主要原料 Methanol 和 2-Azabicyclo[2.2.1]Hept-5-En-3-One
📜2-氮杂双环[2.2.1]庚-5-烯-3-酮置于盐酸,水,Sodium Hydride体系中,用 异丙醚 用作溶剂,化学反应 31.0H,反应生成甲基(1S,4R)-4-氨基-2-环戊烯-1-羧酸酯
参考文献:Lipase-Catalyzed Resolution Of 2-Azabicyclo[2.2.1]Hept-5-En-3-Ones
标题:Lipase-Catalyzed Resolution Of 2-Azabicyclo[2.2.1]Hept-5-En-3-Ones
摘要:The Lipase-Catalyzed Asymmetric Resolution Of 2-Azabicyclo[2.2.1] Hept-5-En-3-Ones Is Reported; Non-Racemic Chiral 2-Azabicyclo[2.2.1]Hept-5-En-3-Ones Were Obtained Conveniently By Lipase-Catalyzed Enantioselective Transesterification Or Hydrolysis Of N-Hydroxymethyl-2-Azabicyclo[2.2.1]Hept-5-En-3-One Or N-Acyloxymethyl-2-Azabicyclo[2.2.1]Hept-5-En-3-One.
Doi:10.1016/0957-4166(96)00293-5
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2905121000-正丙醇
2912110000-甲醛 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
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