专利号:US-2024075466-A1 优先权日:2021-04-09 标 题:One-Pot Synthesis of Transition Metal-Promoted Chabazites 发明人:VAN TENDELOO LEEN; SCHUETZE FRANK-WALTER; VERHEYEN ELKE JANE JUNE 权利人:UMICORE AG & CO KG 摘要:The invention provides methods for a one-pot synthesis of molecular sieves of the CHA-type. The method uses molecular and non-molecular sieves as sources of silicon and aluminum. A first OSDA is selected from tetraethylenepentamine (TEPA) and triethy-lenepentamine (TETA). The synthesis mixture comprises a first metal selected from copper, iron and zinc. Optionally, the synthesis mixture may furthermore comprise a second OSDA and/or a second metal selected from manganese, cesium, magnesium, calcium, strontium, barium, yttrium, titanium, zirconium, niobium, iron, zinc, silver, lanthanum, cerium, praseodymium, neodymium, promethium, samarium, europium, gadolinium, terbium, dysprosium, holmium, erbium, thulium, ytterbium, lutetium and mixtures thereof. The molecular sieves of the CHA-type obtainable by the method can be used as SCR-catalytically active substances for the removal of nitrogen oxides from exhaust gases of combustion engines.
专利号:US-8748660-B2 优先权日:2012-07-09 标题:Process for the synthesis of antiepileptic drug lacosamide 发明人:MURUGAN MUTHUKRISHNAN; MUJAHID MOHAMMAD; MAJUMDAR PRASHANT PRAMOD 权利人:MURUGAN MUTHUKRISHNAN; MUJAHID MOHAMMAD; MAJUMDAR PRASHANT PRAMOD; COUNCIL SCIENT IND RES 摘要:The present invention relates to the improved and efficient process for the synthesis of antiepileptic drug Lacosamide in high enantiopurity (>98% ee) and better yield. More particularly, the present invention relates to improved and efficient, cost effective process for synthesis of desired (R) isomer of Lacosamide starting from commercially available (S)-benzyl glycidyl ether.
专利号:US-4288608-A 优先权日:1978-06-01 标题:Synthesis of anthracyclines 发明人:JOHNSON FRANCIS; KIM KYOUNG S 权利人:RESEARCH CORP 摘要:There is provided a novel method of synthesizing certain heterocyclic quinones. In particular there is provided a novel and regiospecific synthesis of 9-acetyl-6,11-dihydroxy-4-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-quinone (7,9-dideoxydaunomycinone) which is known intermediate in the synthesis of daunomycinone. There is also provided a method of preparing analogs of 7,9-dideoxydaunomycinone which thus provide for the preparation of known and desired analogs of daunomycinone. Daunomycinone is a known compound which is an intermediate in the preparation of the clinically accepted naturally-occurring antitumor antibiotics daunomycin and its derivitive adriamycin.
专利号:US-3956184-A 优先权日:1974-04-24 标题:Method of preparing silver catalyst for synthesis of formaldehyde by oxidizing methyl alcohol 发明人:KRUGLIKOV ANATOLY ABRAMOVICH; YAKOVENKO ZEMFIRA IVANOVNA; ROZNINA MARINA IVANOVNA; ROGACHEVA ANNA MALOFEEVNA; BELOUSOV GERMAN IVANOVICH 权利人:KRUGLIKOV ANATOLY ABRAMOVICH; YAKOVENKO ZEMFIRA IVANOVNA; ROZNINA MARINA IVANOVNA; ROGACHEVA ANNA MALOFEEVNA; BELOUSOV GERMAN IVANOVICH 摘要:The method of preparing a silver catalyst for synthesis of formaldehyde by oxidizing methyl alcohol which consists in that a carrier is impregnated with an aqueous or an aqueous-alcohol solution containing complex ions of silver having the general formula [Ag(X) n ] + or [Ag(Y) 2 ] - , where X is ammonia, ethylenediamine, triethylenetetramine or triaminotriethylamine, Y is a thiocyanate, cyanide, acetate, or hydroxyl ion, and n is 1 or 2. The impregnated carrier is processed, at a temperature of from 10° - 100°C, with a reducing agent taken in the quantity sufficient to reduce the silver completely from said ion. The thus-prepared catalyst is dried at a temperature of from 80° to 400°C. It is recommended that the catalyst be washed with water before drying. The thus-prepared catalyst has a highly developed active surface with a small content of silver (the specific surface of the catalyst is 0.7 - 7 square meters per gram, with the metal silver content of the catalyst being from 5 - 10 per cent by weight). The catalyst is highly active and has good selectivity in the process of formaldehyde synthesis from methyl alcohol. The yield of formaldehyde with the proposed catalyst is from 75 - 80 per cent, calculating with reference to the passed methyl alcohol, with the selectivity of the process being from 89 - 95 per cent.
专利号:US-5523411-A 优先权日:1994-03-14 标题 :Synthesis of mitomycin and its analogs 发明人:JIMENEZ LESLIE; WANG ZHENG 权利人:UNIV RUTGERS 摘要:The present invention relates to the synthesis of mitomycin and analogs thereof that are useful as anticancer antibiotics. The invention further relates to analogs of mitomycin, which can be prepared according to the methods of synthesis provided. The synthetic method of the invention provides for reacting a derivitized indole with a dialkylvinylsulfonium salt to yield a tricyclic skeleton having the precursors of the fourth ring in one step, followed by an oxidation step or steps to close the fourth ring and prepare mitomycin or a related compound.
专利号:US-4000169-A 优先权日:1975-01-27 标题 :Asymmetric synthesis of optically active compounds 发明人:CHAN KA-KONG; SAUCY GABRIEL 权利人:HOFFMANN LA ROCHE 摘要:Asymmetric synthesis of optically active 3,7,11-trimethyl-dodecan-1-ol, an intermediate for producing optically active vitamin E, from isovaleraldehyde or prenal including intermediates in this synthesis.
摘要:Koo, S., Science of Synthesis, (2010) 45, 1356. 摘要:Black, D. A.; Fagnou, K., Science of Synthesis, (2010) 45, 591. 摘要:Ito, S.; Morita, N., Science of Synthesis, (2010) 45, 471. 摘要:McKenna, C. E.; Kashemirov, B. A.; Błażewska, K. M., Science of Synthesis, (2009) 42, 833. 摘要:Negishi, E.; Wang, G., Science of Synthesis, (2009) 46, 332.