CAS: 97-97-2; Dimethylchloroacetal

上下游产品

CAS号67-56-1 甲醇 | CAS号108-05-4 乙酸乙烯酯 | CAS号2280-44-6 D-glucopyranose | CAS号75-07-0 乙醛 | CAS号10257-28-0 D-吡喃葡萄糖 | CAS号95684-29-0 2-chloro-1-(2-c... | CAS号107-25-5 乙烯基甲醚 | CAS号124-41-4 甲醇钠 | CAS号123-63-7 三聚乙醛 | CAS号41683-62-9 1,2-Dichloro-1-... | CAS号105649-50-1 2-methylidene-1... | CAS号5555-00-0 2-甲基-3-呋喃甲酰氯 | CAS号40015-15-4 二甲醇缩甲硫基乙醛 | CAS号38711-20-5 (二甲氨基)乙醛缩二甲醇 | CAS号51673-84-8 乙二醛二甲基缩醛 | CAS号22633-57-4 4-(2,2-二甲氧基乙基)吗啉 | CAS号90-02-8 水杨醛 | CAS号25347-49-3 1-ethyl-4-[2-(4... | CAS号26972-56-5 N-(2,2-dimethox... | CAS号96-50-4 2-氨基噻唑

氯乙醛,甲醇置于对甲苯磺酸体系中,用 氯仿 作为反应溶剂,化学反应 7.0H,以99.7%的收率获得产物2-氯乙醛缩二甲醇
参考文献:Process For Preparing Chloroacetaldehyde Acetals
标题:Process For Preparing Chloroacetaldehyde Acetals
摘要:该发明涉及一种制备单元,二元或更高官能度脂肪族醇的氯乙醛缩醛的方法,其中氯乙醛缩醛是在存在待缩醛的醇和酸催化剂的情况下,通过使用卤代溶剂辅助共沸蒸馏去除水从水溶性氯乙醛溶液中获得的.

专利信息

专利号:US-9422259-B2
优先权日:2011-01-18
标题:Synthetic transtaganolide and basiliolide products, derivatives thereof, and synthesis methods thereof
发明人：NELSON HOSEA; MURAKAMI KEI; VIRGIL SCOTT C; STOLTZ BRIAN M; GORDON JONATHAN R
权利人:CALIFORNIA INST OF TECHN
摘要:Compounds represented by Formula I are provided that include synthetic transtaganolide and basiliolide products. Derivatives of these compounds and methods of synthesis are also provided.

专利号:WO-2014202765-A1
优先权日:2013-06-21
标题 :Preparation of chiral 1-methyl-2,3,4,5-1h-benzodiazepines via asymmetric reduction of alpha-substituted styrenes
发明人：STAVBER GAJ; GAZIC SMILOVIC IVANA; CLUZEAU JEROME; RICHTER FRANK
权利人:LEK PHARMACEUTICALS
摘要:The present invention provides an asymmetric and economic synthesis of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H-benzo[d]azepine via novel intermediates applying an asymmetric enzymatic, biomimetic or catalytic reduction. The present invention also provides a novel green asymmetric catalytic reduction adapted for an aqueous medium to be applied in the synthesis of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1 H-benzo[d]azepine or novel intermediates.

专利号:WO-2021229605-A1
优先权日:2020-05-14
标 题 :Process for preparation of savolitinib and its intermediates
发明人：ORUGANTI SRINIVAS; SEN SAIKAT; SAMPATH MAGESH; AEDHUNURI ARUN; PATHIVADA DEEPIKA
权利人:Dr Reddys Laboratories Ltd
摘要:The present application relates to a process for preparation of chiral amine fragment (IV) of savolitinib. The present application also relates to a process for preparation of savolitinib using the chiral amine (IV), as prepared by the process of the present application. The present application also discloses new intermediates useful for the synthesis of savolitinib. The present application further relates to crystalline forms of savolitinib, namely AA1, formic acid solvate and AA2. The present application also relates to amorphous solid dispersion of savolitinib.

专利号:US-9278939-B2
优先权日:2013-09-18
标 题:Methods for preparation of (4,6-dihalo-pyrimidin-5-yl)-acetaldehydes
发明人：LU SHAOPO; LI ZHUOCAI
权利人:SUZHOU JONATHAN NEW MATERIAL TECHNOLOGY CO LTD
摘要:This invention relates to the synthesis of chemical compounds and particularly to methods for the preparation of (4,6-dihalo-pyrimidin-5-yl)-acetaldehydes. The methods involve preparing a compound of the following general formula V from a compound of the following general formula IV through hydrolysis under the action of mercury dichloride and calcium carbonate, according to the following equation: n nwherein X is Cl or Br. The methods offer the benefits of use of highly available materials, high step yields, moderate reaction conditions, simply post-processing and purification, and suitability to industrialized production.

专利号:US-5144046-A
优先权日:1991-02-14
标 题 :Synthesis of cyclic ketene acetals
发明人：MATHUR SAUGHAGYA C
权利人:MATHUR SAUGHAGYA C
摘要:An improved process for the preparation of cyclic ketene acetals such as 2-methylene-1,3-dioxepane is provided. This process entails reacting at an elevated temperature a halogenated cyclic ketene acetal such as 2-chloromethyl-1,3-dioxepane with a hydroxide compound such as potassium hydroxide in a non-reactive alcohol such as 2-butanol.

专利号:US-5612484-A
优先权日:1995-05-18
标题:Process for making HIV protease inhibitors
发明人：ASKIN DAVID; SAGER JESS; ROSSEN KAI; VOLANTE RALPH P; REIDER PAUL J
权利人:MERCK & CO INC
摘要:A process for making a clinically efficacious HIV protease inhibitor Compound J eliminates one step in its synthesis, by an improved, alternative synthesis of the 2(S)-4-picolyl-2-piperazine-t-butyl-carboxamide intermediate.