CAS: 702-24-9; 4-Methoxy-N-Methylbenzylamine

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CAS号123-11-5 4-甲氧基苯甲醛; 对甲氧基苯... | CAS号74-89-5 氨基甲烷 | CAS号824-94-2 4-甲氧基苄氯 | CAS号13114-23-3 N-(4-甲氧基亚苄基)甲胺 | CAS号5129-86-2 N-(4-methoxy-be... | CAS号2393-23-9 对甲氧基苄胺 | CAS号100-66-3 苯甲醚 | CAS号2746-25-0 4-甲氧基溴苄 | CAS号3400-22-4 4-甲氧基-N-甲基苯甲酰胺 | CAS号13114-23-3 N-(4-甲氧基亚苄基)甲胺 | CAS号1657-55-2 Benzene,1,1'-(1... | CAS号78507-19-4 4-[(甲氨基)甲基]苯酚 | CAS号84174-20-9 N-Methyl-N-nitr...

N-[(1E)-(4-Methoxyphenyl)Methylene]Methanamine置于sodium Tetrahydroborate体系中,化学反应生成 N-甲基-4-甲氧基苄胺
参考文献:A Mechanistic Approach To The Reaction Between Imines And Sodium Hydrogen Telluride
标题:A Mechanistic Approach To The Reaction Between Imines And Sodium Hydrogen Telluride
摘要:
DOI:10.1016/s0040-4039(00)86114-6

专利信息

专利号:US-8188113-B2
优先权日:2006-09-14
标 题 :Dihydropyridopyrimidinyl, dihydronaphthyidinyl and related compounds useful as kinase inhibitors for the treatment of proliferative diseases
发明人：FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C
权利人:FLYNN DANIEL L; PETILLO PETER A; KAUFMAN MICHAEL D; PATT WILLIAM C; DECIPHERA PHARMACEUTICALS INC
摘要:The present invention relates to novel dihydropyridopyrimidinyl, dihydronaphthyridinyl, and related compounds which are kinase inhibitors and modulator useful for the treatment of various diseases. More particularly, the invention is concerned with such compounds, kinase/compound adducts, methods of treating diseases, and methods of synthesis of the compounds. Preferably, the compounds are useful for the modulation of kinase activity of Raf kinases and disease polymorphs thereof. Compounds of the present invention find utility in the treatment of mammalian cancers and especially human cancers including but not limited to malignant melanoma, colorectal cancer, ovarian cancer, papillary thyroid carcinoma, non small cell lung cancer, and mesothelioma. Compounds of the present invention also find utility in the treatment of rheumatoid arthritis and retinopathies including diabetic retinal neuropathy and macular degeneration.

专利号:WO-2023002323-A1
优先权日:2021-07-19
标 题 :Synthesis of substituted tricyclic amides and analogues thereof

专利号:CN-117730082-A
优先权日:2021-07-19
标 题:Synthesis of substituted tricyclic amides and analogs thereof

专利号:WO-2024256496-A1
优先权日:2023-06-14
标题 :[1,2,4]-triazolo[4,3-b]pyridazine derivatives useful as a medicament
发明人：ELIE JONATHAN; GEORGE PASCAL; MIEGE FRÉDÉRIC; MEIJER LAURENT
权利人:PERHA PHARMACEUTICALS
摘要:The present invention relates to a compound of formula (I) or any of its pharmaceutically acceptable salt. The present invention further relates to a synthesis process for manufacturing compound of formula (I) or any of its pharmaceutically acceptable salts, comprising at least a step of reacting a compound of formula (II) with an amine of formula (IV) NHR5R6 for example in a molar ratio ranging from 1 to 20 eq, with respect to the compound of formula (II), in an aprotic solvent or without solvent or else in a protic solvent.

专利号:RU-2119482-C1
优先权日:1991-01-11
标 题:Acridine derivatives, method of synthesis, pharmaceutical composition and a method of treatment of patients with malignant tumors

专利号:US-9611264-B1
优先权日:2015-09-24
标 题:N-[2-(3-amino-2,5-dimethyl-1,1-dioxido-5,6-dihydro-2H-1,2,4-thiadiazin-5-yl)-1,3-thiazol-4-yl] amides
发明人：BRODNEY MICHAEL AARON; BUTLER CHRISTOPHER RYAN; ZHANG LEI; O'NEILL BRIAN THOMAS; VERHOEST PATRICK ROBERT; SALOMON FERRER ROMELIA DEL CARMEN
权利人:PFIZER
摘要:The present invention is directed to compounds, tautomers and pharmaceutically acceptable salts of the compounds which are disclosed, wherein the compounds have the structure of Formula I, n n n n n n n n n n n n wherein the variables R 1 , R 2 and R 3 are as defined in the specification. Corresponding pharmaceutical compositions, methods of treatment, methods of synthesis, and intermediates are also disclosed.