CAS: 6706-59-8; L-Sorbitol

该化合物是一种糖酒精,在各种食品和药品中通常用作甜食剂和发泡剂;一种无色,无味和湿质晶晶体固体,在水中溶解,使其成为需要保持水分的配方中的有效成分;L-Srogotol具有甜味,大约60%与苏格罗素一样甜,并经常用于无糖产品,因为其热量含量较低;它非致癌性,意味着它不会导致牙齿衰变,因此在牙科护理产品中是一种受欢迎的选择;此外,L-Srocotol呈现一种低色指数,使之适合糖尿病的用途;在稳定性方面,它耐氧化,能够承受一系列pH值,增强各种配方的多功能性.

结构式图片

相似化合物

608-66-2 69-65-8 50-70-4

上下游产品

L-sorbose L-gulose (2R,3S,4S,5S)-2,3,4-Tri-O-benzylhexane-1,2,3,4,5,6-hexol (E)-3-((4R,5S)-5-Benzhydryloxymethyl-2,2-dimethyl-[1,3]dioxolan-4-yl)-propenalD-Sorbose 2R,3S,4S,5S-hexitol hexaacetate 5-Methylfurfural 1-(2-furyl)-1-ethanonecis-cinnamyl-formylamino-malonic acid diethyl estercis-cinnamyl-formylamino-malonic acid diethyl ester formylamino-(3-phenyl-prop-2-ynyl)-malonic acid diethyl ester 1-bromo-3-phenylprop-2-yne c-phenyl-pent-4-enoic acid(+/-)-2-amino-5c-phenyl-pent-4-enoic acidrac-(E)-2-amino-5-phenylpent-4-enoic acid (E,2S)-2-amino-5-phenyl-pent-4-enoic acid 5-phenylpenta-2,4-dienoic acid (R,E)-2-((tert-butoxycarbonyl)amino)-5-phenylpent-4-enoic acid

合成工艺路线路线简述

    📜(E)-3-[(4R,5S)-5-(Benzhydryloxymethyl)-2,2-Dimethyl-1,3-Dioxolan-4-Yl]Prop-2-En-1-Ol置于titanium(Iv) Isopropylate,Sodium Hydroxide,Sodium Tetrahydroborate,次氯酸叔丁酯,Sodium Acetate,Potassium Carbonate,D-(-)-酒石酸二异丙酯,(+)-10-Camphorsulfonic Acid,间氯过氧苯甲酸体系中,用 甲醇,二氯甲烷,叔丁醇 作为反应溶剂,化学反应 0.5H,反应生成 L-山梨糖醇
    参考文献:Total Synthesis Of The L-Hexoses
    标题:Total Synthesis Of The L-Hexoses
    摘要:
    DOI:10.1016/s0040-4020(01)97596-9

    海关参考信息

    专利信息


    专利号:US-2021047609-A1
    优先权日:2018-01-26
    标 题 :Method For Promoting Synthesis Of Sorbitol Dehydrogenase And Coenzyme Pyrroloquinoline Quinone From Gluconobacter Oxydans
    发明人:ZHENG YUGUO; KE XIA; LU YANGHUI; HU ZHONGCE; WU YANG
    权利人:UNIV ZHEJIANG TECHNOLOGY; ZHEJIANG MED XINCHANG PHARM
    摘要:The present invention discloses a method for promoting the fermentation of Gluconobacter oxydans to produce D-sorbitol dehydrogenase and pyrroloquinoline quinone. The method comprises: Gluconobacter oxydans is inoculated to a fermentation culture medium, fermented and cultured under the conditions of 28-32° C. and 150-180 rpm for 6-24 hours, the fermented solution is centrifuged, and wet bacteria are collected, thus acquiring bacteria cells containing D-sorbitol dehydrogenase and pyrroloquinoline quinone. The method promotes the synthesis of coenzyme pQQ and the enzyme activity of per unit volume D-sorbitol dehydrogenase, Gluconobacter oxydans cultured and acquired using the method is biotransformed to synthesize miglitol precursor 6-deoxy-6-amino(N-hydroxyethyl)-α-L-furan sorbose (6NSL), the conversion progress of the product 6NSL is increased by 21-35%, and a biotransformation step cycle is reduced from 48 hours to 36 hours. In addition, under a same substrate concentration (60 g/L), the cumulative concentration of the product 6NSL is increased by 10 g/L or more.

    专利号:US-2015057366-A1
    优先权日:2012-03-05
    标题 :Synthesis of elemicin and topical analgesic compositions
    发明人:LA GRANGE MARTIN JAMES
    权利人:LA GRANGE MARTIN JAMES
    摘要:The present invention is directed to the synthesis of elemicin and its isomeric form, and their use in topical analgesic formulations, including for dental and veterinary use. Various compositions include gels, films, dressings, cavity filling gels, having analgesic and/or antifungal properties.

    专利号:US-5714323-A
    优先权日:1991-08-30
    标题:Over expression of single-stranded molecules
    发明人:OHSHIMA ATUSHI; INOUYE SUMIKO; INOUYE MASAYORI
    权利人:UNIV MEDECINE AND DENTISTRY OF
    摘要:A method of synthesis of new and useful single-stranded DNAs which have a stem-loop configuration (ss-slDNA). The method is an in vivo or an in vitro synthesis. Replicating vehicles which produce these ss-slDNAs. The ss-slDNAs are described. Uses for these slDNAs are disclosed. They can be used for introducing random mutations, they lend themselves for replication by a variant of the PCR method. They can also be used for regulating gene function. Other uses are disclosed.

    专利号:US-6201101-B1
    优先权日:1998-11-19
    标 题:Catalyst and its use for the synthesis of polyol polyethers
    发明人:TOZZOLA GABRIELLA; PO' RICCARDO; CARDI NICOLETTA
    权利人:ENICHEM SPA
    摘要:The present invention relates to a catalyst having general formula (I):wherein: M represents at least one cation of an element selected from earth-alkaline metals belonging to groups IIA, IIIA, VA, or transition metals belonging to groups IIB, IIIB, VB or VIIIB; n represents an integer between 0 and 2 and x is an integer between 2 and 5.The invention also relates to a process for the synthesis of polyol polyethers which uses a catalyst having general formula (I).

    专利号:US-7256251-B2
    优先权日:2001-02-06
    标 题:Methods of synthesis of polymers and copolymers from natural products
    发明人:SWIFT GRAHAM; WESTMORELAND DAVID G; WILLETT JULIOUS L; SHOGREN RANDAL LEE; DOLL KENNETH MICHAEL
    权利人:FOLIA INC
    摘要:Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses.

    专利号:US-11661658-B2
    优先权日:2018-06-15
    标题:Electrochemical synthesis of ammonia
    发明人:HERTZBERG BENJAMIN JOSEPH
    权利人:HERTZBERG BENJAMIN JOSEPH
    摘要:Systems and methods for electrochemical ammonia synthesis comprise electrolytes which have greater efficiency than water, thus leading to cost reductions; and/or cathode catalysts which have lower costs and higher efficiencies in comparison to the iron/nickel catalysts noted above. The electrolyte may be composed primarily of a combination of non-aqueous hydrogen bond donors and acceptors, with high nitrogen solubility and high conductivity. The cathode catalyst may be composed of either a manganese-doped oxide or carbonate material or a two-dimensional carbide or nitride material.

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    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献


    1: Yuan J, Chen Z, Guo Z, Li D, Zhang F, Shen J, Zhang Y, Wang S, Zhuang Z. PbsB Regulates Morphogenesis, Aflatoxin B1 Biosynthesis, and Pathogenicity of Aspergillus flavus. Front Cell Infect Microbiol. 2018 May 17;8:162. doi: 10.3389/fcimb.2018.00162. eCollection 2018.
    2: Azadi S, Sadjady SK, Mortazavi SA, Naghdi N, Mahboubi A, Solaimanian R. Bioprocess and downstream optimization of recombinant human growth hormone in Pichia pastoris. Res Pharm Sci. 2018 Jun;13(3):222-238. doi: 10.4103/1735-5362.228953.
    3: Ambros S, Hofer F, Kulozik U. Protective effect of sugars on storage stability of microwave freeze-dried and freeze-dried Lactobacillus paracasei F19. J Appl Microbiol. 2018 May 31. doi: 10.1111/jam.13935. [Epub ahead of print] doi: 10.1155/2018/3276162. eCollection 2018.

    合成参考文献


    参考文献:10.1007/s13205-018-1251-x
    摘要:Ke X, Wang NN, Yu PH, Lu YH, Hu ZC, Zheng YG. Biosynthesis of miglitol intermediate 6-(N-hydroxyethyl)-amino-6-deoxy-α-l-sorbofuranose by an improved d-sorbitol dehydrogenase from Gluconobacter oxydans. 3 Biotech. 2018 May;8(5):231.
    参考文献:10.1007/bf00428772|10.1007/s001250050066
    摘要:Ling Z, Hannaert JC, Pipeleers D. Effect of nutrients, hormones and serum on survival of rat islet beta cells in culture. Diabetologia. 1994 Jan;37(1):15–21. doi: 10.1007/bf00428772.
    参考文献:10.1023/a:1015872805768
    摘要:Burke DE, Wang BBL, Wan TTH, Diana ML. Exploring Hospitals' Adoption of Information Technology. Journal of Medical Systems. 2002 Aug;26(4):349–55. doi: 10.1023/a:1015872805768.
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