专利号:US-2021047609-A1 优先权日:2018-01-26 标 题 :Method For Promoting Synthesis Of Sorbitol Dehydrogenase And Coenzyme Pyrroloquinoline Quinone From Gluconobacter Oxydans 发明人:ZHENG YUGUO; KE XIA; LU YANGHUI; HU ZHONGCE; WU YANG 权利人:UNIV ZHEJIANG TECHNOLOGY; ZHEJIANG MED XINCHANG PHARM 摘要:The present invention discloses a method for promoting the fermentation of Gluconobacter oxydans to produce D-sorbitol dehydrogenase and pyrroloquinoline quinone. The method comprises: Gluconobacter oxydans is inoculated to a fermentation culture medium, fermented and cultured under the conditions of 28-32° C. and 150-180 rpm for 6-24 hours, the fermented solution is centrifuged, and wet bacteria are collected, thus acquiring bacteria cells containing D-sorbitol dehydrogenase and pyrroloquinoline quinone. The method promotes the synthesis of coenzyme pQQ and the enzyme activity of per unit volume D-sorbitol dehydrogenase, Gluconobacter oxydans cultured and acquired using the method is biotransformed to synthesize miglitol precursor 6-deoxy-6-amino(N-hydroxyethyl)-α-L-furan sorbose (6NSL), the conversion progress of the product 6NSL is increased by 21-35%, and a biotransformation step cycle is reduced from 48 hours to 36 hours. In addition, under a same substrate concentration (60 g/L), the cumulative concentration of the product 6NSL is increased by 10 g/L or more.
专利号:US-2015057366-A1 优先权日:2012-03-05 标题 :Synthesis of elemicin and topical analgesic compositions 发明人:LA GRANGE MARTIN JAMES 权利人:LA GRANGE MARTIN JAMES 摘要:The present invention is directed to the synthesis of elemicin and its isomeric form, and their use in topical analgesic formulations, including for dental and veterinary use. Various compositions include gels, films, dressings, cavity filling gels, having analgesic and/or antifungal properties.
专利号:US-5714323-A 优先权日:1991-08-30 标题:Over expression of single-stranded molecules 发明人:OHSHIMA ATUSHI; INOUYE SUMIKO; INOUYE MASAYORI 权利人:UNIV MEDECINE AND DENTISTRY OF 摘要:A method of synthesis of new and useful single-stranded DNAs which have a stem-loop configuration (ss-slDNA). The method is an in vivo or an in vitro synthesis. Replicating vehicles which produce these ss-slDNAs. The ss-slDNAs are described. Uses for these slDNAs are disclosed. They can be used for introducing random mutations, they lend themselves for replication by a variant of the PCR method. They can also be used for regulating gene function. Other uses are disclosed.
专利号:US-6201101-B1 优先权日:1998-11-19 标 题:Catalyst and its use for the synthesis of polyol polyethers 发明人:TOZZOLA GABRIELLA; PO' RICCARDO; CARDI NICOLETTA 权利人:ENICHEM SPA 摘要:The present invention relates to a catalyst having general formula (I):wherein: M represents at least one cation of an element selected from earth-alkaline metals belonging to groups IIA, IIIA, VA, or transition metals belonging to groups IIB, IIIB, VB or VIIIB; n represents an integer between 0 and 2 and x is an integer between 2 and 5.The invention also relates to a process for the synthesis of polyol polyethers which uses a catalyst having general formula (I).
专利号:US-7256251-B2 优先权日:2001-02-06 标 题:Methods of synthesis of polymers and copolymers from natural products 发明人:SWIFT GRAHAM; WESTMORELAND DAVID G; WILLETT JULIOUS L; SHOGREN RANDAL LEE; DOLL KENNETH MICHAEL 权利人:FOLIA INC 摘要:Described are polymers and copolymers containing sorbitol, citric acid, starch, aspartic acid, succinic anhydride, adipic acid mixtures thereof, methods of their synthesis and their uses.
专利号:US-11661658-B2 优先权日:2018-06-15 标题:Electrochemical synthesis of ammonia 发明人:HERTZBERG BENJAMIN JOSEPH 权利人:HERTZBERG BENJAMIN JOSEPH 摘要:Systems and methods for electrochemical ammonia synthesis comprise electrolytes which have greater efficiency than water, thus leading to cost reductions; and/or cathode catalysts which have lower costs and higher efficiencies in comparison to the iron/nickel catalysts noted above. The electrolyte may be composed primarily of a combination of non-aqueous hydrogen bond donors and acceptors, with high nitrogen solubility and high conductivity. The cathode catalyst may be composed of either a manganese-doped oxide or carbonate material or a two-dimensional carbide or nitride material.
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合成参考文献
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