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参考文献:Utility Of Tetrathiomolybdate And Tetraselenotungstate: Efficient Synthesis Of Cystine,Selenoystine,And Their Higher Homologues
标题:Utility Of Tetrathiomolybdate And Tetraselenotungstate: Efficient Synthesis Of Cystine,Selenoystine,And Their Higher Homologues
摘要:Efficient Synthesis Of Cystine,Selenoystine,And Their Higher Homologues Like Homo And Bishomo Amino Acid Derivatives From Natural Amino Acid Derivatives Using Tetrathiomolybdate And Tetraselenotungstate Reagents Under Mild And Neutral Conditions Is Reported. The Generality Of The Reaction Has Been Studied By Capping Various Groups To Amino And Carboxyl Components Of Canonical Amino Acids. (C) 2003 Elsevier Science Ltd. All Rights Reserved.
Doi:10.1016/S0040-4039(03)01222-X

专利信息

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人：ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.