CAS: 54230-22-7; 2,3,4,6-Tetrachlorobiphenyl
该化合物是一种属于多氯联苯类别的氯化双联苯化合物,由两只联苯环组成,由一个单一的联结连接,其中四个氯原子替换在联苯结构的2,3,4和6个位置上,该化合物一般为室温固态,具有疏水性,导致水溶解性较低,但有机溶剂溶解性较高. 2,3,4,6-四氯联苯因其稳定性和耐降解性而闻名,使其在环境中具有持久性,已用于各种工业用途,包括电气设备中的电动液和热传输液,然而,由于其毒性特性和生物累积潜力,该化合物被归类为一种环境污染物,并须接受监管审查.
- 英文名称2,3,4,6-Tetrachlorobiphenyl
- 中文名称2,3,4,6-四氯联苯
- IUPAC名称1,2,3,5-tetrachloro-4-phenylbenzene
- 其它别名2,3,4,6-Tetrachloro-1,1'-biphenyl; 2,3,4,6-Tetrachlorobiphenyl; PCB 62
- CAS编号54230-22-7
- MFCD编号:MFCD00661132
- FDA UNII编号:668WHK8XYK
- 分子式:C12H6Cl4分子量:291.99
- 产品CID: 2497528
- 产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃
- 相似结构搜索
- 产品信息参考
;;;; - InChIKey: HOBRTVXSIVSXIA-UHFFFAOYSA-N
- 1S/C12H6Cl4/c13-8-6-9(14)11(15)12(16)10(8)7-4-2-1-3-5-7/h1-6H
- 计算化学: 氢键受体数*氢键供体数0.0可旋转键数1.0
MSDS等安全信息
- 危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website. - 安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)
上下游产品
2,3,4,6-tetrachloroaniline benzene 2,3,4,5,6-pentachlorobiphenyl 2,3,4-trichlorobiphenyl 2,4,5-trichlorobiphenyl 2,4,6-trichlorobiphenyl 2,3,6-trichlorobiphenyl合成工艺路线路线简述
📜2,3,4,6-四氯苯胺,苯置于sodium Acetate,亚硝酸体系中,化学反应生成 2,3,4,6-四氯联苯
参考文献:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
标题:Physical,Spectral And Chromatographic Properties Of All 209 Individual Pcb Congeners
摘要:Physical,Spectral And Chromatographic Data For All 209 Individual Pcb Congeners Is Presented. The Individual Congeners Were Synthesized And Then Isolated And Purified. Recent Emphasis On The Source Of The Toxicity Of Commercial Pcb Formulations Has Increased The Need For A Complete Set Of The Pcb Congeners. Through The Use Of Two Capillary Gc Columns: 40% octadecyl/ 15% Phenyl Methyl Siloxane And 50% Phenyl Methyl Siloxane,It Was Possible To Separate 201 Pcb Congeners With Only Four Unresolved Pairs. The Data Compiled In This Study For All 209 Congeners Will Aid In The Identification Of Selected Individual Components Of These Environmental Pollutants. The Use Of This Data Also Presents The Opportunity For The Improved Quantification Of The Commercial Pcb Formulations.
DOI:10.1016/0045-6535(95)00140-4
海关参考信息
- 2903911000-邻二氯苯
- 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
合成参考文献
摘要:T14: Lewis RJ (1996). Sax's Dangerous Properties of Industrial Materials. 9th ed. Volumes 1-3. New York, NY: Van Nostrand Reinhold.
摘要:L4: ATSDR - Agency for Toxic Substances and Disease Registry (2000). Toxicological profile for polychlorinated biphenyls. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L134: ATSDR - Agency for Toxic Substances and Disease Registry (2001). Minimal Risk Levels (MRLs) for Hazardous Substances. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA).
摘要:L135: International Agency for Research on Cancer (2014). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans.
摘要:T6: World Health Organization (1993). Environ Health Criteria 140: Polychlorniated Biphenyls and Terphenyls.
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