CAS: 509-40-0; Diaboline
- 英文名称Diaboline
- 中文名称达波灵碱
- IUPAC名称1-((4bR,7aS,8aR,13R,13aR,13bS)-13-hydroxy-5,6,7a,8,8a,11,13a,13b-octahydro-7,9-methanooxepino[3,4-a]pyrrolo[2,3-d]carbazol-14(13H)-yl)ethan-1-one
- CAS编号509-40-0
- FDA UNII编号:9ZF1MM6TXS
- 分子式:C21H24N2O3分子量:352.43
- 产品CID: 1498138
- 同类组份化合物CAS11032-42-1 (HCl)509-40-0 (free base)
- 产品分类有机原料 → 生物碱及其衍生物 → 马钱子生物碱
物理性质
MSDS等安全信息
上下游产品
Henningsamine, O-Acetyldiaboline A 2871-28-5番木鳖碱 Strychnidin-10-One 57-24-9
去乙酰基达波灵碱 (17R,19E)-17,18-Epoxy-Cur-19-En-17-Ol 466-85-3
23-Isonitrosostrychnine 24180-59-4
(6R,16α,19E)-1-Acetyl-19,20-Didehydro-6-(Ethylthio)-18-[[tris(1-Methylethyl)Silyl]Oxy]-Curan-17-Ol 482351-16-6
(6R,16α,19E)-19,20-Didehydro-6-(Ethylthio)-18-[(4-Methoxyphenyl)Methoxy]-17-[[2-(Trimethylsilyl)Ethoxy]Methoxy]Curan 482351-05-3
(1S,4E,5R,6R)-2-[2,2-Bis(Ethylthio)Ethyl]-2,3,4,5,6,7-Hexahydro-4-[2-[(4-Methoxyphenyl)Methoxy]Ethylidene]-6-[[[2-(Trimethylsilyl)Ethoxy]Methoxy]Methyl]-1,5-Methano-1H-Azocino[4,3-B]Indole 482351-06-4
(5R,6R)-5-[(E)-1-[2,2-Bis(Ethylsulfanyl)Ethylamino]-4-[(4-Methoxyphenyl)Methoxy]But-2-En-2-Yl]-2-(2-Nitrophenyl)-6-(2-Trimethylsilylethoxymethoxymethyl)Cyclohex-2-En-1-One 1027259-59-1
(5R,6R)-5-[(1E)-1-(Hydroxymethyl)-3-[(4-Methoxyphenyl)Methoxy]-1-Propenyl]-2-(2-Nitrophenyl)-6-[[[2-(Trimethylsilyl)Ethoxy]Methoxy]Methyl]-2-Cyclohexen-1-One 482351-07-5
合成工艺路线路线简述
📜番木鳖碱置于吡啶,盐酸,氢氧化钾,氯化亚砜,Sodium Ethanolate,亚硝酸异戊酯体系中,用 甲醇,乙醇 作为反应溶剂,化学反应 10.0H,反应生成 达波灵碱
参考文献:Kapoor,V. K.; Sharma,S. K.; Chagti,K. K.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1988,Vol. 27,# 1-12,P. 641-644
标题:Kapoor,V. K.; Sharma,S. K.; Chagti,K. K.,Indian Journal Of Chemistry-Section B Organic And Medicinal Chemistry,1988,Vol. 27,# 1-12,P. 641-644
海关参考信息
- 2901210000-乙烯
2901220000-丙烯
2902600000-乙苯
2902700000-异丙基苯 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
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供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Ohiri FC, Verpoorte R, Svendsen AB. 12-Hydroxy-ll-methoxy-diaboline: A New Alkaloid from Strychnos spinosa. Planta Med. 1984 Oct;50(5):446-7. doi: 10.1055/s-2007-969763.
193:1178. doi: 10.1038/1931178a0. 47(6):953-7. doi: 10.1021/np50036a007.
46:2812-4. doi: 10.1039/jr9650002812. 44(1):21-7. doi: 10.1055/s-2007-971392.
合成参考文献
参考文献:10.1021/np50012a003
摘要:Marini-Bettolo GB, Messana I, Nicoletti M, Patamia M, Galeffi C. On the alkaloids of Strychnos. XXXV. The occurrence of akagerine in South American Strychnos. J Nat Prod. 1980 Nov;43(6):717–20. doi: 10.1021/np50012a003.
摘要:Acta Pharmaceutica Suecica., 7(329), 1970 []
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