CAS: 42740-50-1; 2,2',3,3',4,4',5',6-Octachlorobiphenyl

该化合物是多氯联苯(PCB)家族的成员,该家族由碳,氢和氯原子组成的合成有机化学品组成. PCB196的特点是结构复杂,其特点是联苯有多个氯原子,联苯有多个氯原子,有6个氯替代成分.这种化合物一般是一种粘性,非易燃和挥发性低的油性液体.多氯联苯,包括多氯联苯196,因其化学稳定性,耐降解性和疏水特性而著称,这些化学品助长了其在环境中的持久性.它们被广泛用于电器设备,热传导液和各种工业应用中的添加剂.然而,由于多氯联苯在食物链中的毒性和生物积累潜力,许多国家已基本禁止或限制多氯联苯. 多氯联苯196与其他多氯联苯一样,对环境和健康构成风险,包括潜在的致癌效应和内分泌干扰,因此需要谨慎处理和处置.

英文名称2,2',3,3',4,4',5',6-Octachlorobiphenyl
中文名称2,2',3,3',4,4',5,6'-八氯联苯
IUPAC名称1,2,3,4-tetrachloro-5-(2,3,4,6-tetrachlorophenyl)benzene
其它别名2,2',3,3',4,4',5,6'-°Ctachlorobiphenyl; 2,2',3,3',4,4',5',6-°Ctachlorobiphenyl; 2,3,4,5,2',3',4',6'-°Ctachlorobiphenyl
CAS编号42740-50-1
MFCD编号:MFCD00674486
FDA UNII编号:3W40E7L2DO
分子式:C12H2Cl8分子量:429.77
产品CID: 1439620
产品分类分析化学 → 食品安全 → 二噁英，多氯联苯，呋喃

相似结构搜索
InChIKey: BQFCCUSDZLKBJG-UHFFFAOYSA-N
1S/C12H2Cl8/c13-4-2-6(15)9(17)11(19)7(4)3-1-5(14)10(18)12(20)8(3)16/h1-2H
计算化学: 氢键受体数*氢键供体数*可旋转键数1.0

MSDS等安全信息

危险描述Not Classified
Reported as not meeting GHS hazard criteria by 3 of 3 companies. For more detailed information, please visit ECHA C&L website.
安全声明The mechanism of action varies with the specific PCB. Dioxin-like PCBs bind to the aryl hydrocarbon receptor, which disrupts cell function by altering the transcription of genes, mainly be inducing the expression of hepatic Phase I and Phase II enzymes, especially of the cytochrome P450 family. Most of the toxic effects of PCBs are believed to be results of Ah receptor binding. Other PBCs are believed to interfere with calcium channels and/or change brain dopamine levels. PCBs can also cause endocrine disurption by altering the production of thyroid hormones and binding to estrogen receptors, which can stimulate the growth of certain cancer cells and produce other estrogenic effects, such as reproductive dysfunction. They will bioaccumulate by binding to receptor proteins such as uteroglobin. (A3, A4, A30, A66)

合成工艺路线路线简述

📜3-氯苯胺置于亚硝酸异戊酯体系中,化学反应生成 2,2',3,3',4,4',5,6'-八氯联苯
参考文献:Sundstroem,G.,Acta Chemica Scandinavica (1947),1973,Vol. 27,P. 1109-1111
标题:Sundstroem,G.,Acta Chemica Scandinavica (1947),1973,Vol. 27,P. 1109-1111