CAS: 29816-01-1; H-Gly-Sar-Oh
该化合物是氨基酸甘油和沙库辛的二酸,其特征为相对简单的结构,包括一个矿体组,一个碳球酸组和从沙库辛衍生出来的侧链.该化合物表面一般为白色,外观为白色,在水中可溶解,因为其极性.甘基锡辛,对生物化学研究和药物应用,尤其是与peptide合成和蛋白质相互作用有关的研究感兴趣.其特性可能包括特定熔点和稳定在某些pH条件下,使之适合各种实验室应用.此外,它可能展示生物活动,有可能影响代谢途径或作为酶反应的子体.
- 英文名称H-Gly-Sar-Oh
- 中文名称甘氨酰肌氨酸
- IUPAC名称N-glycyl-N-methylglycine
- 其它别名Glycine, Glycyl-N-Methyl-; [(Ammonioacetyl)(Methyl)Amino]Acetate; 2Je8Sg6Vdt; Tritiated Glycylsarcosine; [(Aminoacetyl)(Methyl)Amino]Acetic Acid; 19Z49Huf4G; N-Glycyl-N-Methylglycine; Gly-Sarcosi
- CAS编号29816-01-1
- MFCD编号:MFCD00038193
- EINECS号:249-875-2
- FDA UNII编号:2JE8SG6VDT
- 分子式:C5H10N2O3分子量:146.15
- 产品CID: 1280008
- 产品分类有机原料→生命科学→氨基酸及其衍生物→甘氨酸及其衍生物
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📜苄氧羰基-甘氨酰-肌氨酸置于甲醇,钯,溶剂黄146体系中,化学反应生成甘氨酰肌氨酸
参考文献:Bergmann Et Al.,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1932,Vol. 212,P. 72,79
标题:Bergmann Et Al.,Hoppe-Seyler'S Zeitschrift Fur Physiologische Chemie,1932,Vol. 212,P. 72,79
海关参考信息
- 2912110000-甲醛
2912120000-乙醛
2915110000-甲酸
2915211900-乙酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
专利信息
专利号:WO-2023057548-A1
优先权日:2021-10-07
标题:Ccr6 receptor modulators
发明人：AISSAOUI HAMED; ALLEMANN OLIVER; CAROFF EVA; MEYER EMMANUEL; RICHARD-BILDSTEIN SYLVIA
权利人:IDORSIA PHARMACEUTICALS LTD
摘要:The present invention relates to compounds of Formula (I), their synthesis and use as CCR6 receptor modulators for the prevention or treatment of e.g. inflammatory/autoimmune diseases/disorders and cancer.
专利号:CN-102604989-B
优先权日:2009-09-09
标 题 :A kind of methyltransferase gene and application in betaine synthesis pathway
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主要参考文献
[参考文献]: Luckose F, Et Al. Effects Of Amino Acid Derivatives On Physical, Mental, And Physiological Activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1144.[参考文献]: Chenlin Shen, Et Al. Intestinal Absorption Mechanisms Of Mtbh, A Novel Hesperetin Derivative, In Caco-2 Cells, And Potential Involvement Of Monocarboxylate Transporter 1 And Multidrug Resistance Protein 2. Eur J Pharm Sci. 2015 Oct 12:78:214-24.
[参考文献]: Griet Van Zeebroeck, Et Al. Transport And Signaling Via The Amino Acid Binding Site Of The Yeast Gap1 Amino Acid Transceptor. Nat Chem Biol. 2009 Jan;5(1):45-52.
[参考文献]: Hamed Gilzad Kohan, Et Al. Synthesis And Characterization Of A New Peptide Prodrug Of Glucosamine With Enhanced Gut Permeability. Plos One. 2015 May 15;10(5):E0126786.
[参考文献]: International Transporter Consortium, Et Al. Membrane Transporters In Drug Development. Nat Rev Drug Discov. 2010 Mar;9(3):215-36.
合成参考文献
参考文献:10.1152/ajprenal.00030.2008
摘要:Sala-Rabanal M, Loo DDF, Hirayama BA, Wright EM. Molecular mechanism of dipeptide and drug transport by the human renal H+/oligopeptide cotransporter hPEPT2. American Journal of Physiology-Renal Physiology. 2008 Jun;294(6):F1422–32. doi: 10.1152/ajprenal.00030.2008.
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