CAS: 26663-77-4; Methyl Benzimidazole-5-Carboxylate

相似化合物

15788-16-6 58442-17-4 106429-29-2

上下游产品

1H-苯并咪唑-5-羧酸 5-Benzimidazolecarboxylic Acid 15788-16-6
2,3-二氢-2-硫酮-1H-苯并咪唑-5-甲酸甲酯 2-Thio-2,3-Dihydro-1H-Benzo[d]Imidazole-5-Carboxylic Acid Methyl Ester 64375-41-3
5-羟甲基-1H-苯并咪唑 (1H-Benzo[d]Imidazol-5-yl)Methanol 106429-29-2

1H-苯并咪唑-5-羧酸置于氯化亚砜体系中,用 甲醇 用作溶剂,化学反应 7.0H,以489 Mg的收率获得苯并咪唑-5-羧酸甲酯
参考文献: Aryl And Heteroaryl-Carboxamide Substituted Heteroaryl Compounds As Tyk2 Inhibitors[fr] Composés Hétéroaryle Substitués Par Aryle Et Hétéroaryle-Carboxamide Utiles En Tant Qu'Inhibiteurs De Tyk2
标题: Aryl And Heteroaryl-Carboxamide Substituted Heteroaryl Compounds As Tyk2 Inhibitors[fr] Composés Hétéroaryle Substitués Par Aryle Et Hétéroaryle-Carboxamide Utiles En Tant Qu'Inhibiteurs De Tyk2
摘要:公开了一种化合物,其为新颖的羧酰胺取代化合物,化学式为(i);以及其制备方法,包含它们的药物组成物和它们作为酪氨酸激酶2(tyk2)抑制剂在治疗中的用途.

专利信息

专利号:EP-1836163-B1
优先权日:2004-12-23
标题 :Pyrrolidine derivatives for the treatment of a disease depending on the activity of renin
发明人：BREITENSTEIN WERNER; COTTENS SYLVAIN; EHRHARDT CLAUS; JACOBY EDGAR; LORTHIOIS EDWIGE LILIANE JEANNE; MAIBAUM JUERGEN KLAUS; OSTERMANN NILS; SELLNER HOLGER; SIMIC OLIVER
权利人:NOVARTIS AG
摘要:Novel 3-mono-, 3,4-di- and 3,4,4,-tri-substituted pyrrolidine compounds, these compounds for use in the diagnostic and therapeutic treatment of a warm-blooded animal, especially for the treatment of a disease (=disorder) that depends on inappropriate activity of renin; the use of a compound of that class for the preparation of a pharmaceutical formulation for the treatment of a disease that depends on inappropriate activity of renin; the use of a compound of that class in the treatment of a disease that depends on inappropriate activity of renin; pharmaceutical formulations comprising a said substituted pyrrolidine compound, and/or a method of treatment comprising administering a said substituted pyrrolidine compound, a method for the manufacture of said substituted pyrrolidine compounds, and novel intermediates and partial steps for their synthesis are described. The substituted pyrrolidine compounds are especially of the formula I wherein the substituents are as described in the specification.

专利号:RU-2023713-C1
优先权日:1989-12-18
标 题:Method of synthesis of benzimidazole derivatives or their salts

专利号:RU-2057126-C1
优先权日:1989-10-24
标 题:Benzimidazole derivatives, method of their synthesis and pharmaceutical composition on their basis

专利号:SK-10102003-A3
优先权日:2001-02-13
标题:Acylated indanylamines, a pharmaceutical composition thereof, a method of synthesis and their use as a medicament