专利号:US-2023286918-A1 优先权日:2020-07-02 标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat 发明人:JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER 权利人:AKEBIA THERAPEUTICS INC 摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.
专利号:US-2011229397-A1 优先权日:2008-10-03 标 题:Process and apparatus for continuous flow synthesis of nanocrystals 发明人:BARTEL JOSEPH; MCKENZIE LALLIE 权利人:LIFE TECHNOLOGIES CORP 摘要:Novel reactor, systems and methods of preparing nanocrystals in a continuous flow-through process are provided. The novel reactor is highly configurable and can be modified to achieve desired reaction times of a flow through mixture. The reactor is designed to provide uniform, efficient heating of the reaction mixture.
专利号:US-11865519-B2 优先权日:2018-09-06 标题:Noble metal-promoted IN2O3 catalyst for the hydrogenation of CO2 to methanol 发明人:STEWART JOSEPH; CURULLA-FERRE DANIEL; PEREZ-RAMIREZ JAVIER; MONDELLI CECILIA; FREI MATTHIAS 权利人:TOTAL SE; ETH ZUERICH 摘要:Method to prepare a catalyst for use in a process for the synthesis of methanol, comprising indium oxide in the form of In2O3, and at least one additional metal selected from a noble metal; and in that the average particle size of said noble metal phase is, preferably at least 0.05 nm, and less than 5 nm as determined by STEM-EDX, characterized in that the catalyst is prepared by co-precipitation of a saline solution at a pH above 8.5 comprising an indium salt and a salt of the at least one additional metal selected from a noble metal and optionally further comprising a salt of the at least one alkaline earth metal.
专利号:US-11629137-B2 优先权日:2017-04-24 标 题:Methods of manufacturing of niraparib 发明人:STEWART ALISTAIR; TOTO ANTHONY JOSEPH; CHEN FRANK XING; WU GEORGE 权利人:TESARO INC 摘要:Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib.
专利号:US-2025242336-A1 优先权日:2021-10-04 标 题 :A catalyst for the conversion of co2 to co and process for the preparation thereof 发明人:RAJA THIRUMALAISWAMY; GOPINATH CHINNAKONDA SUBRAMANIAN; MHAMANE NITIN BHARAT; RANJAN RAVI 权利人:COUNCIL SCIENT IND RES 摘要:The present invention relates to catalyst. Co3O4 nanocube or In2O3 with novel characterization features for the synthesis of CO, which is used as a reducing agent in the production of direct reduced metal from metal ore or mixture of metal oxides.
专利号:US-4320109-A 优先权日:1979-06-29 标题:Immunoradiometric assay employing terminal radionuclide labeling and synthesis of conjugates for such assay 发明人:WOLF WALTER; NAKAMURA ROBERT M; GOKCE ATA; TUBIS MANUEL; O'BRIEN TIMOTHY J 权利人:UNIV SOUTHERN CALIFORNIA 摘要:An immunoradiometric assay in which an antigen is reacted to its specific antibody, which complex is then separated and further reacted with a second, universal antibody. This second, universal antibody contains a chelating moiety, such as transferrin, capable of binding specifically and strongly short-lived radionuclides. The second complex, once formed is reacted with a radionuclide and the radio-activity is measured, determining thereby the quantity of the unknown antigen originally present.
参考标题:Metal Bis-Triflimide Compounds And Methods For Synthesis Of Metal Bis-Triflimide Compounds 摘要:A Metal Bis-Triflimide Compound Having The Formula: [m X ] N+ [(N(So 2 Cf 3 ) 2 ) (Nx-Yz) ] (Nx-Yz)− [ly] Z− Where M Is A Metal Selected From The Metals In Groups 5 To 10, 12 And 14 To 16 And Cu, Au, Ca, Sr, Ba, Ra, Y, La, Ac, Hf, Rf, Ga, In, Tl, Ce, Pr, Nd, Pm, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Lu And The Actinides; L Is A Negative Or Neutral Ligand; N Is 2,3,4,5,6,7 Or 8; X Is Greater Than Or Equal To 1 Y Is 0,1,2,3,4,5,6,7 Or 8; And Z Is 0,1,2,3 Or 4.
合成参考文献
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