CAS: 19783-14-3; Lead,Dihydrate

该化合物是一种无机化合物,通常用于化学合成,电镀和其他铅基材料的前体;它看起来像一种白色晶状固体,水溶性低,适合受控降水反应;该化合物因其在生产氧化铅,稳定剂和电池材料方面的作用而受到重视;它与酸和基底的反作用允许在工业过程中进行多种用途的用途;妥善处理由于其毒性而必不可少,需要遵守安全协议;铅氢化物往往因其在化学反应中一贯纯度和可预见性而得到偏好,确保专门应用的可靠性能.

结构式图片

欧盟法规

《欧盟PIC法规》REACH注册ECHA物质ECHA物质OtherC&L通报REACH预注册

合成工艺路线路线简述

    碳酸铅(II) 反应生成氫氧化鉛
    参考文献:Hostettler,J. E.;Bishop,M. D.;Patel,B. B.,World Oil,211,(1990) N,C. 79,81,83,85-87
    标题:Hostettler,J. E.;Bishop,M. D.;Patel,B. B.,World Oil,211,(1990) N,C. 79,81,83,85-87

    专利信息


    专利号:US-2024158926-A1
    优先权日:2022-11-03
    标 题 :Electrochemical synthesis of hydroxyvaleric acid from levulinic acid
    发明人:HOLEWINSKI ADAM; DE SOUZA LUCAS FRANCISCO WILLIAN
    权利人:UNIV COLORADO REGENTS
    摘要:Disclosed herein are methods of electrochemical synthesis of hydroxyvaleric acid from levulinic acid. For example, disclosed herein are methods comprising electrochemical synthesis of hydroxyvaleric acid from levulinic acid, wherein the method is conducted in an electrochemical cell wherein a working electrode is in electrochemical contact with an aqueous electrolyte and levulinic acid, wherein the method comprises applying a potential to electrochemically reduce the levulinic acid to form hydroxyvaleric acid. Also disclosed herein are methods of synthesizing gamma-valerolactone from hydroxyvaleric acid, the method comprising acid-catalyzed esterification. Also disclosed herein are methods of use of the products produced by any of the methods herein.

    专利号:US-2023286918-A1
    优先权日:2020-07-02
    标 题:Manufacturing process for 3,5-dichloropicolinonitrile for synthesis of vadadustat
    发明人:JURKAUSKAS VALDAS; JUNG YOUNG CHUN; KWON TAESOO; KANNAN ARUNACHALAM; GONDI VIJAYA BHASKER
    权利人:AKEBIA THERAPEUTICS INC
    摘要:Disclosed herein are methods and processes of preparing vadadustat or a pharmaceutically acceptable salts thereof, and intermediates (e.g., a compound of Formula (I), (I-F), (II), or (IV), or a pharmaceutically acceptable salts thereof) useful for the synthesis of vadadustat.

    专利号:US-5753726-A
    优先权日:1995-12-20
    标 题:Synthesis of modified epoxy resins for cathodic electrodeposition with catalyst deactivation and diol modification
    发明人:REUTER HARDY; JOUCK WALTER; OTT GUENTHER
    权利人:BASF LACKE & FARBEN
    摘要:Epoxy resins for preparing water-dispersible binders for cathodic electrodeposition coating materials, the epoxy resin being preparable by reacting a) polyepoxides having at least one glycidyl group per molecule b) and, optionally, up to 60% by weight, based on the overall epoxy resin reaction product, of aliphatic and/or alicyclic hydroxy compounds having preferably two or on average less than two hydroxyl groups per molecule and a molecular weight of less than 9000 g/mol, c) in the presence of a catalyst consisting of neutral metal salts, such as alkali metal salts and alkaline earth metal salts, zinc salts and nickel salts of tetrafluoroboric, tetrachloroboric, hexafluoro- antimonic,hexachloroantimonic,hexafluorophosphoric, perchlorate and periodic acid, and d) adding a deactivating agent which prevents the epoxy groups reacting further or effectively reduces the rate of such reaction as soon as the phenolic hydroxyl groups have already substantially reacted and at least 0.6% by weight of epoxy groups are still present, based on the overall weight of the epoxy resin reaction product.\\!

    专利号:US-11629137-B2
    优先权日:2017-04-24
    标 题:Methods of manufacturing of niraparib
    发明人:STEWART ALISTAIR; TOTO ANTHONY JOSEPH; CHEN FRANK XING; WU GEORGE
    权利人:TESARO INC
    摘要:Disclosed herein are methods and processes of preparing niraparib and pharmaceutically acceptable salts thereof, and intermediates and their salts useful for the synthesis of niraparib.

    专利号:US-6136229-A
    优先权日:1998-10-15
    标题 :Method for the mechanochemical preparation of high performance ceramics
    发明人:CUI CHANGXING; SU JI; BAUGHMAN RAY H
    权利人:ALLIED SIGNAL INC
    摘要:Disclosed are mechanochemical processes for the synthesis of high performance electroceramics from organometallic precursors, and compositions resulting from the processes.

    专利号:WO-2008044544-A1
    优先权日:2006-10-04
    标题 :Fine particle of hydroxide and/or oxide and process for producing the same
    发明人:HORIGUCHI SHINICHI; ARIZONO JYUNICHI; OOSHIMA YASUHIRO
    权利人:NISSHIN SPINNING; HORIGUCHI SHINICHI; ARIZONO JYUNICHI; OOSHIMA YASUHIRO
    摘要:Fine particles of a hydroxide and/or oxide which are produced by electrodialysis; and a process for producing the fine particles. A conductive liquid which is a poor solvent for the hydroxide and/or oxide to be generated in a synthesis chamber is used as a synthesis-chamber liquid. The synthesis chamber is used in combination with a desalting chamber separated from the synthesis chamber by a cation-exchange membrane, the desalting chamber being filled with an aqueous electrolyte solution containing metal ions as a raw material for the hydroxide and/or oxide. A voltage not lower than the theoretical water electrolysis voltage is applied to the chambers. The fine hydroxide and/or oxide particles, which are produced through electrodialysis, are reduced in equipment cost and production cost.
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    合成参考文献


    摘要:
    摘要:ACGIH - Documentation of the TLVs and BEIs, 7th Ed. Cincinnati: ACGIH Worldwide, 2020.
    摘要:T17: Baselt RC (2000). Disposition of Toxic Drugs and Chemicals in Man, 5th ed. Foster City, CA: Chemical Toxicology Institute.
    摘要:A22: Hashemzadeh-Gargari H, Guilarte TR: Divalent cations modulate N-methyl-D-aspartate receptor function at the glycine site. J Pharmacol Exp Ther. 1999 Sep;290(3):1356-62.
    摘要:L136: ATSDR - Agency for Toxic Substances and Disease Registry (2007). Toxicological profile for lead. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). http://www.atsdr.cdc.gov/toxprofiles/tp13.html
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