CAS: 13894-21-8; Ethynyl P-Tolyl Sulfone

该化合物是一种有机化合物,其特点是存在一个苯乙烯组和一个聚氨酯,这种化合物一般是固体,在标准条件下以其稳定性而闻名.乙基苯基混合物的特点是碳原子之间有三重联系,这给人带来了独特的反应,特别是结合反应和有机合成的构件.分子中的丙基硫酸成分有助于其溶性,并能够影响其再活动性,使其在各种化学应用中有用,包括制药和材料科学.这种乙基化合物由于苯乙烯和芳香系统之间的混凝结,往往表现出有趣的电子特性.安全数据表明,与许多磺酰化合物一样,应谨慎处理,因为它在接触时可能构成健康风险.

结构式图片

相似化合物

3185-99-7 340771-31-5 22821-76-7

欧盟法规

ECHA物质C&L通报

上下游产品

1-ethynylsulfanyl-4-methyl-benzene 4-(toluene-4-sulfonyl)-isoxazol-5-ylamine trimethylsilyl p-tolylsulfonylacetylene ethynylphenyl-iodonium-1,1,1-trifluoromethanesulfonatetrans-1-Propylamino-2-p-tolylsulfonyl-acetylen trans-1-Dimethylamino-2-p-tolylsulfonyl-aethylen (E)-N,N-diethyl-2-((4-methylphenyl)sulfonyl)ethene-1-amine -2-tosylethylene(E)-1--2-tosylethylene

合成工艺路线路线简述

    📜(E)-1-(Phenylseleno)-2-(P-Tolylsulfonyl)Ethene Se-Oxide 以 氯仿,苯 用作溶剂,化学反应 5.0H,以51%的收率获得乙炔基对甲苯基砜
    参考文献:Selenosulfonation Of Acetylenes: Preparation Of Novel .Beta.-(Phenylseleno)Vinyl Sulfones And Their Conversion To Acetylenic And .Beta.-Functionalized Sulfones
    标题:Selenosulfonation Of Acetylenes: Preparation Of Novel .Beta.-(Phenylseleno)Vinyl Sulfones And Their Conversion To Acetylenic And .Beta.-Functionalized Sulfones
    摘要:
    Doi:10.1021/jo00166A030

    海关参考信息

    专利信息


    专利号:US-6384228-B2
    优先权日:1998-05-26
    标题 :Method for synthesis of halopyridyl-azacyclopentane derivative and intermediate thereof
    发明人:NODE MANABU; NAKAMURA DAISAKU; FUJIWARA TOSHIO; ICHIHASHI SHOGO
    权利人:NIHON MEDIPHYSICS CO LTD
    摘要:The present invention relates to a method for synthesis of an optically active halopyridyl-azacyclo-pentane derivative and the intermediate thereof which comprises preparing an optically active allene-1,3-dicarboxylic acid ester derivative from an optically active acetonedicarboxylic acid ester derivative and then proceeding through a 7-azabicyclo[2.2.1]heptane derivative to obtain the objective product.

    专利号:US-7109377-B2
    优先权日:1996-10-16
    标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products
    发明人:SCHREIBER STUART L; SHAIR MATTHEW D; TAN DEREK S; FOLEY MICHAEL A; STOCKWELL BRENT R
    权利人:HARVARD COLLEGE
    摘要:The present invention provides complex compounds reminiscent of natural products and libraries thereof, as well as methods for their production. The inventive compounds and libraries of compounds are reminiscent of natural products in that they contain one or more stereocenters, and a high density and diversity of functionality. In general, the inventive libraries are synthesized from diversifiable scaffold structures, which are synthesized from readily available or easily synthesizable template structures. In certain embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from a shikimic acid based epoxyol template. In other embodiments, the inventive compounds and libraries are generated from diversifiable scaffolds synthesized from the pyridine-based template isonicotinamide. The present invention also provides a novel ortho-nitrobenzyl photolinker and a method for its synthesis. Furthermore, the present invention provides methods and kits for determining one or more biological activities of members of the inventive libraries. Additionally, the present invention provides pharmaceutical compositions containing one or more library members.

    专利号:US-2003082830-A1
    优先权日:1996-10-16
    标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

    专利号:US-2002010339-A1
    优先权日:1998-05-26
    标 题:Method for synthesis of halopyridyl-acyclopentane derivative and intermediate thereof

    专利号:WO-0006525-A9
    优先权日:1998-07-25
    标题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

    专利号:WO-0006525-A2
    优先权日:1998-07-25
    标 题:Synthesis of combinatorial libraries of compounds reminiscent of natural products

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    主要参考文献

    [参考文献]: Elena Petit, Et Al. Tosvinyl And Besvinyl As Protecting Groups Of Imides, Azinones, Nucleosides, Sultams, And Lactams. Catalytic Conjugate Additions To Tosylacetylene. J Org Chem. 2014 Sep 19;79(18):8826-34.
    [参考文献]: Takeshi Hanazawa, Et Al. Efficient And Practical Method For Synthesizing Optically Active Indan-2-Ols By The Ti(O-I-Pr)(4)/2 I-Prmgcl-Mediated Metalative Reppe Reaction. J Org Chem. 2003 Jun 13;68(12):4980-3.

    合成参考文献


    摘要:Shinmyozu, T.; Shibahara, M., Science of Synthesis, (2010) 45, 1305.
    摘要:Joule, J. A., Science of Synthesis Knowledge Updates, (2018) 2, 54.
    摘要:Spitzner, D., Science of Synthesis Knowledge Updates, (2016) 1, 34.
    摘要:Udmark, J.; Brøndsted Nielsen, M., Science of Synthesis Knowledge Updates, (2014) 3, 362.
    摘要:Kawęcki, R., Science of Synthesis Knowledge Updates, (2018) 4, 302.
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