CAS: 1034-49-7; (Bromomethyl)Triphenylphosphonium Bromide

相似化合物

5293-84-5 1779-49-3 3020-28-8

上下游产品

Hydroxymethyl-triphenyl-phosphonium-bromid ethylene dibromide triphenylphosphine 1,1-dibromomethane 9-(bromomethylene)-9H-fluorene 1,1,3-Trimethyl-2-(4-brom-3-methyl-butadien-1,3-yl)-cyclohexen-2, β-Ionyliden-brommethan 9-{2-[1-Bromo-meth-(Z)-ylidene]-4,4-diphenyl-but-3-enylidene}-9H-fluorene bromomethylenecyclohexane

Hydroxymethyltriphenylphosphonium Bromide置于三溴化磷体系中,用 苯 用作溶剂,化学反应生成溴甲基三苯基溴化磷
参考文献:膦亚甲基化学的研究:Xiii.合成三苯基膦-卤代亚甲基和-二卤代亚甲基的途径
标题:膦亚甲基化学的研究:Xiii.合成三苯基膦-卤代亚甲基和-二卤代亚甲基的途径
摘要:苯基锂对溴化(溴甲基)三苯基action的作用导致三苯基膦溴亚甲基(形式h /提取)和三苯基膦亚甲基(形式br /提取)几乎等摩尔的混合物.与碘化(碘甲基)三苯基phosph形成三苯基膦碘亚甲基和三苯基膦亚甲基的混合物,其中后者的含量约为三倍.
Doi:10.1016/s0022-328X(00)80365-4

专利信息

专利号:US-5292977-A
优先权日:1992-02-05
标题:Palladium catalyzed alkylative cyclization useful in synthesis of vitamin D and analogues
发明人：TROST BARRY M; DUMAS JACQUES
权利人:UNIV LELAND STANFORD JUNIOR
摘要:An alkylative cycloaddition method is provided that is particularly useful for the synthesis of many of the Vitamin D analogues with differing side chains. Thus, a preferred synthesis is of Vitamin D analogues having a side chain R 1 where a substantially geometrically pure first precursor having the structure ##STR1## and a second precursor are provided, the second precursor being a 1,7 enyne. These precursors are reacted in the presence of a palladium catalyst to form compounds having the structure ##STR2## where R 2 hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group, and R 3 is hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group.

专利号:US-5446225-A
优先权日:1992-02-05
标题:Palladium catalyzed akylative cyclization useful in syntheses of Vitamin D and analogues
发明人：TROST BARRY M; DUMAS JACQUES
权利人:UNIV LELAND STANFORD JUNIOR
摘要:An alkylative cycloaddition method is provided that is particularly useful for the synthesis of many of the Vitamin D analogues with differing side chains. Thus, a preferred synthesis is of Vitamin D analogues having a side chain R 1 where a first precursor having the structure ##STR1## with X being a halide or a pseudo halide, and a second precursor are provided, the second precursor being a 1,7 enyne. These precursors are reacted in the presence of a palladium catalyst to form compounds having the structure ##STR2## where R 2 is hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group, and R 3 is hydrogen, hydroxyl, lower alkoxy, fluorine, or a protecting group.

专利号:US-5266708-A
优先权日:1989-12-01
标题 :New intermediates, process for their preparation, and their use for the synthesis of vitamins A and E
发明人：CHABARDES PIERRE F; DUHAMEL LUCETTE; DUHAMEL PIERRE; GUILLEMONT JEROME; POIRIER JEAN-MARIE
权利人:RHONE POULENC NUTRITION ANIMAL
摘要:New intermediates and processes for the preparation of vitamins A and E, which are the acetals of 5,6-dihalo-3-methyl-3-hydroxyhexanal or of 6-halo-3-hydroxy-3-methyl-5-hexenal or 3-methyl-3-hydroxy-5-hexenal, as well as processes for making the intermediates. After dehydrohalogenation and dehydration these intermediates are condensed directly with β-ionone or with 2-methyl-2-heptene-6-one to synthesize vitamins A and E respectively.

专利号:US-5120864-A
优先权日:1989-12-01
标 题:Intermediates, process for their preparation, and their use for the synthesis of vitamins a and e
发明人：CHARBARDES PIERRE F; DUHAMEL LUCETTE; DUHAMEL PIERRE; GUILLEMONT JEROME; POIRIER JEAN-MARIE
权利人:RHONE POULENC NUTRITION ANIMAL
摘要:New intermediates and processes for the preparation of vitamins A and E, which are the acetals of 5,6-dihalo-3-methyl-3-hydroxyhexanal or of 6-halo-3-hydroxy-3-methyl-5-hexenal or 3-methyl-3-hydroxy-5-hexenal, as well as processes for making the intermediates. After dehydrohalogenation and dehydration these intermediates are condensed directly with β-ionone or with 2-methyl-2-heptene-6-one to synthesize vitamins A and E respectively.

专利号:EP-0432021-A1
优先权日:1989-12-01
标题 :Intermediates, procedure for their preparation and their use in the synthesis of vitamins A and E

专利号:WO-9316022-A1
优先权日:1992-02-05
标题 :Palladium catalyzed alkylative cyclization useful in synthesis of vitamin d and analogues