CAS: 78346-95-9; 1-(2,4-Diamino-4-Oxo-Butanoyl)Pyrrolidine-2-Carboxylic Acid

📜N2-(Tert-Butoxycarbonyl)-L-Asparaginyl-L-Proline 以99%的收率获得
参考文献:Onoprienko,L. V.;Mixaleva,I. I.;Lunev,V. E.;Nesmeyanov,V. A.;Ivanov,+,Bioorgan. Ximiya,15,(1989) N,S. 908-921
标题:Onoprienko,L. V.;Mixaleva,I. I.;Lunev,V. E.;Nesmeyanov,V. A.;Ivanov,+,Bioorgan. Ximiya,15,(1989) N,S. 908-921

专利信息

专利号:WO-9521249-A1
优先权日:1994-02-03
标题:A cassette to accumulate multiple proteins through synthesis of a self-processing polypeptide
发明人：BEACHY ROGER N; MARCOS JOSE F
权利人:SCRIPPS RESEARCH INST
摘要:A cassette for simultaneous expression of two or more heterogenous peptides in equimolar amounts and based upon the nuclear inclusion (NIa) protease from tobacco etch potyvirus. The heterogenous peptides are translated and incorporated into a polypeptide that also includes the protease which releases the heterologous proteins post translationally by autoproteolytic reaction.

专利号:EP-2588602-A1
优先权日:2010-07-01
标题:Variants of glucoamylase
发明人：DEGN PETER EDVARD; BOTT RICHARD R; VROEMEN CASPER WILLEM; SCHEFFERS MARTIJN SILVAN; AEHLE WOLFGANG; PETERSEN ELIN
权利人:DUPONT NUTRITION BIOSCI APS; DANISCO US INC
摘要:The present invention relates to combinatorial variants of a parent glucoamylase that have altered properties for reducing the synthesis of condensation products during hydrolysis of starch. Accordingly the variants of a parent glucoamylase are suitable such as for use within brewing and glucose syrup production. Also disclosed are DMA constructs encoding the variants and methods of producing the glucoamylase variants in host cells.

专利号:US-7569541-B2
优先权日:2003-06-02
标题 :Method for synthesizing conformationally constrained peptides, peptidomimetics and the use thereof as synthetic vaccines
发明人：PLUSCHKE GERD; KIENZL URSULA; ROBINSON JOHN; ZURBRIGGEN RINALDO
权利人:MYMETICS CORP
摘要:The present invention relates to methods for synthesizing conformationally constrained peptides and cyclic peptidomimetics obtainable by these methods which are conformationally constrained due an internal cross-link. This cross-link is formed between the side chain of an amino acid residue or analog and a (2S, 4S)4-functionalized proline residue. The invention further relates to the use of (2S, 4S)-4-functionalized proline residues as building units in the synthesis of such peptidomimetics and to the use thereof as antigens, alone or in combination with suitable immunopotentiating delivery systems, for example immunopotentiating reconstituted influenza virosomes to elicit an immune response in a mammal. Moreover, the invention also relates to pharmaceutical compositions containing the same.

专利号:US-5116946-A
优先权日:1988-06-08
标题:Synthetic, immunologically active peptides useful for the preparation of antimalarial vaccines
发明人：VERDINI ANTONIO S; PESSI ANTONELLO; BONELLI FABIO
权利人:ENIRICERCHE SPA
摘要:Synthetic peptides constituted by at least two repeating, consecutive units of asparaginyl-proline (Asn-Pro)n sequence, are described. The peptides are powerful immunogens, capable of inducing in laboratory animals the formation of a high concentration of antibodies capable of reacting both with the (Asn-Pro)n peptides, and with the immunodominant epitope of the circumsporozoite protein of Plasmodium falciparum. The peptides, which can be obtained in a pure form by chemical synthesis, are particularly useful for preparing antimalarial vaccines and diagnostic kits for the determination of malaria in man.

专利号:ES-2385028-T3
优先权日:2001-03-02
标 题 :Synthesis of tetradentate peptide-chelate conjugates for the diagnosis of colorectal cancer

专利号:ES-2435576-T3
优先权日:2007-12-21
标 题 :Peptide to activate the synthesis of aquaporins