CAS: 7464-14-4; 2-Hydroxy-5-Methyl-3-Nitropyridine

主要参考文献

参考标题: Proteasome Activity Enhancing Compounds Composés Renforçant L'Activité Des Protéasomes
摘要:The Present Invention Is Directed To Compounds Having The Formula (I), (II), (III), (Iv), And (V), Compositions Thereof, The Methods Of Synthesis Of The Compouds Of Interest, And To Methods For The Treatment Of A Condition Associated With A Dysfunction In Proteostasis, Such As Cancer, Inflammatory Conditions, Neurodegeneration, Metabolic Conditions, Comprising Administering An Effective Amount Of A Compound Of The Invention.

合成参考文献

参考文献:10.1016/j.bbrc.2023.08.050
摘要:Ikeda Y, Davis MI, Sumita K, Zheng Y, Kofuji S, Sasaki M, Hirota Y, Pragani R, Shen M, Boxer MB, Takeuchi K, Senda T, Simeonov A, Sasaki AT. Multimodal action of KRP203 on phosphoinositide kinases in vitro and in cells. Biochemical and Biophysical Research Communications. 2023 Oct;679():116–21. doi: 10.1016/j.bbrc.2023.08.050.