CAS: 520-09-2; 5-(Bis(2-Chloroethyl)Amino)-6-Methylpyrimidine-2,4(1H,3H)-Dione

该化合物是一种化学化合物,其独特的结构特征是含有一种以二(2-氯乙基)氨基组和甲基组替代的火水晶环,该化合物在医药化学中的潜在用途值得注意,特别是因其能够干扰细胞过程而作为抗沙毒剂.氯乙基组的存在表明可导致核糖核糖核糖核酸的回燃活动,这是癌症治疗中经常使用的一种机制.该化合物一般在室温下是固态的,在有机溶剂中可能表现出中等溶性.其化学特性,如稳定性和再活性,可能受到氯乙基化合物的存在和丙酰胺环的总体电子环境的影响.安全和处理防范措施对于与氯乙基组的潜在毒性至关重要.

结构式图片

MSDS等安全信息

上下游产品

H-pyrimidine-2,4-dione5-[bis-(2-hydroxy-ethyl)-amino]-6-methyl-1H-pyrimidine-2,4-dione 5-amino-6-methyluracil

合成工艺路线路线简述

    📜5-氨基-2,4-二羟基-6-甲基嘧啶置于氯化亚砜,溶剂黄146体系中,化学反应生成 多潘
    参考文献:Chang; Yuean,Yaoxue Xuebao/acta Pharmaceutica Sinica,1958,Vol. 6,P. 139
    标题:Chang; Yuean,Yaoxue Xuebao/acta Pharmaceutica Sinica,1958,Vol. 6,P. 139

    海关参考信息

    专利信息


    专利号:WO-2013098428-A1
    优先权日:2011-12-30
    标题:Mechanochemical method for synthesizing doped anatase-phase titanium-dioxide particles
    发明人:FERNANDEZ HEVIA DANIEL
    权利人:INAEL ELECTRICAL SYSTEMS S A; FERNANDEZ HEVIA DANIEL
    摘要:Mechanochemical method for synthesizing doped anatase-phase titanium-dioxide particles with controlled morphology for promoting the exposure of reactive faces; the invention relates to the field of the synthesis of doped anatase-phase titanium-dioxide particles; the main use of these materials lies in two areas: (1) in environmental protection and remediation (by way of the decontamination of liquid and gaseous effluents); and (2) in the energy sector, by way of the photocatalytic production of hydrogen.

    专利号:JP-2000514870-A
    优先权日:1996-07-11
    标 题 :Electrically assisted synthesis of films and particles with precisely tuned properties

    专利号:CN-114957017-A
    优先权日:2022-05-18
    标 题 :A kind of organic electroluminescent compound and its synthesis method and application

    专利号:WO-2006100888-A1
    优先权日:2005-03-22
    标 题:Material for organic el device, organic el device, display and illuminating device
    发明人:SEKINE NOBORU; OSHIYAMA TOMOHIRO; NISHIZEKI MASATO; KATOH EISAKU
    权利人:KONICA MINOLTA HOLDINGS INC; SEKINE NOBORU; OSHIYAMA TOMOHIRO; NISHIZEKI MASATO; KATOH EISAKU
    摘要:Disclosed is a material for organic EL devices which is high in synthesis yield and luminous efficiency while having long emission life. Also disclosed are an organic EL device using such a material, and a display and illuminating device using such an organic EL device. The organic EL material is composed of a metal complex having a partial structure represented by the general formula (1) below, and is characterized by having at least one substituent in a ligand part which suppresses bidentate coordination.

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    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:K.L. Evstratova and A.I. Ivanova. Farmatsiya (Moscow) 17, 41 (1968); CA 69, 46128a.
    摘要:RAVINA A, ELOY P. [Current status of anticancer chemotherapy. II. Study of some alkylating agents: cyclophosphamine, degranol, novoembioquine, dopan, sarcolvsin. asaline]. Presse Med (1893). 1960 Oct 29;68():1789–92.
    摘要:LARIONOV L. Dopan and related compounds. Cancer Chemother Rep. 1961 Jun;12():205–6.
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