CAS: 474-00-0; (-)-Eburnamonine

上下游产品

Ent-19-Oxo-Eburnamonine 110421-51-7
(+/-)-Eburnamine
长春酸胺 Vincaminsaeure 28152-73-0
(+)-Eburnamenine 517-30-6
Ent-1β-Ethyl-4-Oxo-1,2,3,4,6,7,12,12β-Octahydro-1,3-Cycloindolo<2,3-A>Quinolizin-3β-Carboxylic Acidmethylester 113974-84-8
3-((1R,12Br)-1-Ethyl-1,2,3,4,6,7,12,12B-Octahydro-Indolo[2,3-A]Quinolizin-1-yl)-2-[(E)-Hydroxyimino]-Propionic Acid Methyl Ester 86708-31-8
2-((1R,12Br)-1-Ethyl-1,2,3,4,6,7,12,12B Octahydroindolo[2,3-A]Quinolizin-1-yl)Ethanol 1395097-95-6
(1Rs,12Brs)-1-Ethyl-1,2,3,4,6,7,12,12B-Octahydroindolo[2,3-A]Quinolizine-1-Ethanol 119459-52-8
(-)-1β-Cyanomethyl-1α-Ethyl-1,2,3,4,6,7,12,12Bα-Octahydro-Indolo<2,3-A>Quinolizine 53430-06-1
(3,4,6,7,12,12B-Hexahydro-2H-Indolo[2,3-A]Quinolizin-1-Ylidene)-Acetic Acid Ethyl Ester 38199-33-6

📜3-((1R,12Br)-1-Ethyl-1,2,3,4,6,7,12,12B-octahydro-Indolo[2,3-A]Quinolizin-1-yl)-2-[(E)-Hydroxyimino]-Propionic Acid Methyl Ester置于sodium Hydroxide体系中,用 水,乙二醇 作为反应溶剂,化学反应 3.0H,以84%的收率获得产物象牙酮宁
参考文献:Czibula,Laszlo; Nemes,Andras; Visky,Gyoergy,Liebigs Annalen Der Chemie,1993,# 3,P. 221-230
标题:Czibula,Laszlo; Nemes,Andras; Visky,Gyoergy,Liebigs Annalen Der Chemie,1993,# 3,P. 221-230

专利信息

专利号:US-11897827-B1
优先权日:2022-11-22
标 题 :Carbon isotope exchange mediated by vanadium complexes
发明人：BUKHRYAKOV KONSTANTIN
权利人:BUKHRYAKOV KONSTANTIN; THE FLORIDA INTERNATIONAL UNIV BOARD OF TRUSTEES
摘要:The subject invention provides catalytical compounds/complexes, compositions comprising such compound/complex, synthesis of the compounds/complexes, and methods of using such compounds/complexes as catalysts in, for example, carbon isotope exchange (CIE) on target bioactive molecules. Methods that allow CIE directly on drug candidates are of great importance to chemistry, biology, and medicine. Especially valuable are catalytic procedures that rely on a limited collection of available labeled materials. The instant method comprises converting a methyl group to terminal â•?CH2 utilizing transfer dehydrogenation catalysts to enable V-based olefin metathesis, followed by a hydrogenation step. The one-pot strategy allows the formal methylation/demethylation sequence and can be applied to an assortment of alkyl-containing compounds.

专利号:US-3753995-A
优先权日:1971-01-06
标题:Process and intermediates in the preparation of eburnamonine
发明人：MARTEL J; COSTEROUSSE G
权利人:ROUSSEL UCLAF
摘要:THE OBJECT OF THIS INVENTION IS A NEW PROCESS OF PREPARATION OF ($) EBURNAMONINE OF THE FORMULA: 12-(O=),13A-(CH3-CH2-)-2,3,4A,5,6,12,13,13A-OCTAHYDRO- 1H-INDOLO(3,2,1-DE)PYRIDO(3,2,1-IJ)(1,5)NAPHTHYRIDINE IT IS KNOWN THAT EBURANAMONINE HAS BEEN ISOLATED FROM SEVERAL PLANT SPECIES SUCH AS VINCA MINOR AND HUNTERIA EBURNEA. EBURNAMONINE POSSESSES INTERESTING PHARMACOLOGICAL PROPERIES, IT PROVOKES A HYPERTENSION ACCOMPANIED BY A RESPIRATORY AND CARDIAC STIMULATION AND AN INCREASE OF TONICITY. IN ADDITION, EBURNAMONINE CAN SERVE AS STARTING MATERIAL IN THE SYNTHESIS OF KNOWN ANALOGOUS COMPOUNDS DISPLAYING AN INTERESTING PHYSIOLOGICAL ACTIVITY.

专利号:JP-S61158981-A
优先权日:1977-07-25
标题 :Synthesis of compounds of the eburnamonin group

专利号:EP-0001021-B1
优先权日:1977-07-25
标 题 :Derivatives of pentacyclic alcaloids, method for their preparation, application in the synthesis of products of the eburnamonine group and pharmaceutical compositions

专利号:EP-0001021-A2
优先权日:1977-07-25
标题 :Derivatives of pentacyclic alcaloids, method for their preparation, application in the synthesis of products of the eburnamonine group and pharmaceutical compositions

专利号:EP-0001021-A3
优先权日:1977-07-25
标 题:Derivatives of pentacyclic alcaloids, method for their preparation, application in the synthesis of products of the eburnamonine group and pharmaceutical compositions