CAS: 4587-33-1; (S)-4-Nitrophenyl 4-Amino-2-((Tert-Butoxycarbonyl)Amino)-4-Oxobutanoate

相似化合物

104199-82-8 3256-57-3 71989-17-8

上下游产品

CAS号100-02-7 对硝基苯酚 | CAS号7536-55-2 B°C-L-天冬酰胺 | CAS号13303-10-1 (4-硝基苯基)碳酸叔丁酯 | CAS号30044-67-8 B°C-L-天冬酰胺 | CAS号73024-87-0 PGLU-ASN-GLY | CAS号100-02-7 对硝基苯酚 | CAS号7536-55-2 B°C-L-天冬酰胺

氟甲酸叔丁酯置于n,N'-二环己基碳二亚胺体系中,用 四氢呋喃,1,4-二氧六环,水,N,N-二甲基甲酰胺 作为反应溶剂,化学反应生成 丁氧羰基-L-天冬酰胺对硝苯基酯
参考文献:Schnabel,E. Et Al.,Justus Liebigs Annalen Der Chemie,1971,Vol. 743,P. 57-68
标题:Schnabel,E. Et Al.,Justus Liebigs Annalen Der Chemie,1971,Vol. 743,P. 57-68

专利信息

专利号:US-2024218014-A1
优先权日:2022-11-21
标 题:Synthesis of a cyclic peptide
发明人：BAUR PIUS BRUNO; CLEATOR EDWARD; DENIAU GILDAS; EISELE FRANK; FLÖGEL OLIVER; HUSTE ANJA; KEHL MARCEL ROMAN; LÖWENECK MARKUS; SILVA ROLANDO RAVELO; VORBERG RAFFAEL
权利人:JANSSEN PHARMACEUTICA NV
摘要:Processes for performing peptide synthesis, particularly for cyclic peptide synthesis are generally described. Reaction intermediates of the peptide synthesis are also described.

专利号:US-2004110228-A1
优先权日:2002-04-01
标 题:Combinatorial organic synthesis of unique biologically active compounds
发明人：MCALPINE SHELLI R; TAYLOR RACHEL E; BOLLA MEGAN L; SEGALL ANCA M
摘要:The invention provides a method for making a combinatorial library of cyclic compounds, such as Holliday junction-trapping compounds, comprising the steps of (a) obtaining a plurality of trimers according to the generic structure X 1- X 2- X 3 , wherein X 1 , X 2 and X 3 can be independently any naturally or nonnaturally occurring amino acids or peptidomimetics thereof; (b) optionally coupling a spacer S to the trimer at either end; (c) cyclizing two trimers or trimer-spacer conjugates in a head-to-tail orientation; thereby obtaining a combinatorial library of compounds, wherein the library does not include an unmodifed or naturally occurring Holliday Junction-trapping compounds. The invention additionally provides methods macrocyclic compounds that are synergimycin derivatives.

专利号:US-4105602-A
优先权日:1975-02-10
标 题 :Synthesis of peptides with parathyroid hormone activity
发明人：COLESCOTT ROBERT L; TREGEAR GEOFFREY W
权利人:ARMOUR PHARMA
摘要:Resin peptides useful in the preparation of peptides having biological activity, and particularly such resin peptides containing R--CH 2 --O--Phe--Asn at one end of an amino acid chain, R being the resin and Phe and Asn being the residues of the amino acids phenylalanine and asparagine; and processes for the preparation of such resin peptides. Resin peptides are disclosed which contain amino acid chains identical with the amino acid chains of natural peptides having biological activity. Other resin peptides are disclosed which contain amino acid chains in which the amino acid residues differ in kind and sequence from amino acid chains of natural biologically active peptides but from which peptides having biological acitivity may be derived.

专利号:US-4212795-A
优先权日:1978-11-13
标题:Cyclization of peptides
发明人：HUGHES JOHN L; LIU ROBERT C; SEYLER JAY K
权利人:ARMOUR PHARMA
摘要:The synthesis of a disulfide cyclic peptide by preparing an intermediate peptide containing two cysteine moieties, each of which is protected by an n-alkylthio group, or when one of such moieties is in an amino terminal position, this one moiety may be protected by a cysteine group while the other is protected by an n-alkylthio group, and placing such intermediate peptide in a solution substantially free of oxygen and preferably at a pH of from 5 to 10 until rearrangement has taken place, to yield a cyclic disulfide peptide. The disclosure also embraces said intermediate peptides as new compounds and the processes by which they are prepared.

专利号:US-4000259-A
优先权日:1975-06-16
标 题:Cyclic dodecapeptide analogs of somatostatin and intermediates
发明人：GARSKY VICTOR M
权利人:AMERICAN HOME PROD
摘要:Cyclic dodecapeptide analogs of somatostatin without cysteine amino acid residues and intermediates obtained in the synthesis of such compounds are described. These cyclic dodecapeptides inhibit the secretion of glucagon and hence have application in the treatment of diabetes mellitus.

专利号:US-4242238-A
优先权日:1976-02-13
标 题 :Synthesis of peptides
发明人：BOSSINGER CHARLES D; COLESCOTT ROBERT L; KAISER EMIL
权利人:ARMOUR &
摘要:Resin peptides useful in preparing peptides having biological activity, and particularly such resin peptides containing ALA-GLU-CH 2 - R at one end of an amino acid chain, R being the resin and ALA and GLU being the residues of the amino acids alanine and glutamic acid; and processes for the preparation of such resin peptides. Resin peptides including ACTH 1-28 are disclosed which have adrenocorticotropic activity along with processes for their preparation.