CAS: 34976-39-1; 6-Ethyl-3-Methyl-2,9-Dioxo-[1,3]Thiazolo[5,4-F]Quinoline-8-Carboxylic Acid
- 英文名称6-Ethyl-3-Methyl-2,9-Dioxo-[1,3]Thiazolo[5,4-F]Quinoline-8-Carboxylic Acid
- 中文名称噻克沙星
- IUPAC名称6-ethyl-3-methyl-2,9-dioxo-2,3,6,9-tetrahydrothiazolo[5,4-f]quinoline-8-carboxylic acid
- 其它别名Tioxacin; Tioxic acid
- CAS编号34976-39-1
- FDA UNII编号:0K40CNM74K
- 分子式:C14H12N2O4S分子量:304.32
- 产品CID: 1354688
- 产品分类原料药 → 人工合成抗感染类药 → 喹诺酮类药
物理性质
- 沸点519.9 °C at 760mmHg
- 闪点268.2 °C
- 密度1.513g/cm3
- PSA:109.54
- LogP:1.633
- 折射率1.688
- 蒸汽压1.23E-11 mmHg at 25 °C
- 储存条件Dry, dark and at 0 -4 C for short term (days to weeks) or -20 C for long term(months to years).
- 产品应用该化合物是一种杀菌剂. TIXACINS 给出了一个可溶性综合体, 含有脂胺, 并且对G(+) 和G(-) 细菌, 包括抗内分泌酸的ESHERICHIA COLI 和 98种此类酸的PSEUDOMONAS EERUGINOSA 具有最高的活动能力.
MSDS等安全信息
上下游产品
f]quinoline-8-carboxylic acid methyl ester6-ethyl-3-methyl-2,9-dioxo-2,3,6,9-tetrahydro-thiazolo[5,4-f]quinoline-8-carboxylic acid methyl ester f]quinoline-8-carboxylic acid ethyl ester6-ethyl-3-methyl-2,9-dioxo-2,3,6,9-tetrahydro-thiazolo[5,4-f]quinoline-8-carboxylic acid ethyl ester f]quinolinium; methyl sulfate8-carboxy-6-ethyl-3-methyl-2-methylsulfanyl-9-oxo-6,9-dihydro-thiazolo[5,4-f]quinolinium; methyl sulfate f]quinoline-8-carboxylic acid ethyl ester6-ethyl-2-methylsulfanyl-9-oxo-6,9-dihydro-thiazolo[5,4-f]quinoline-8-carboxylic acid ethyl ester合成工艺路线路线简述
海关参考信息
- 2902200000-苯
2905110000-甲醇
2912110000-甲醛
2915110000-甲酸 - 💡 提示：海关信息按照顺序优先匹配，如需确认的海关信息，请参考相关资料。
- 详情请参考：📖 海关编码查询和海关进出口税则
供应商参考报价(招募中)
品牌试剂参考报价(招募中)
📌 第三方产品分析报告
主要参考文献
1: Uekama K, Hirayama F, Takasugi N. [Soluble complex formation of 6-ethyl-2,3,6 ,9-tetrahydro-3-methyl-2,9-dioxothiazolo-[5,4-f]quinoline-8-carboxylic acid (tioxacin) with aliphatic amines (author's transl)]. Yakugaku Zasshi. 1979 May;99(5):476-82. Japanese. doi: 10.1248/yakushi1947.99.5_476.
合成参考文献
参考文献:10.1007/978-981-99-2302-1_24
摘要:Singh R, Tandon V. Antibiotics: Past, Present, Future, and Clinical Pipeline. 2023. In: Recent Advances in Pharmaceutical Innovation and Research.
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