CAS: 1641-40-3; 1,2-Phenylene Phosphorochloridite

该化合物是一个混合循环化合物,在一种苯并二氮二氧磷和氧气的框架中具有独特的结构,其特点是循环安排,包括一个含有磷和两个氧原子的五人环以及一个氯化芳香系统;氯原子的存在有助于其反应和各种化学反应的潜在应用;这种性质化合物通常具有中等稳定性,但在标准条件下具有中等稳定性,但可能对水和空气敏感,需要小心处理;已知苯并二氮二氧磷孔结构有可能用于开发含磷材料,包括协调化学中的离心和有机合成中的中间体;此外,由于磷原子的存在,这种化合物可能会显示出有趣的生物活动,使其成为医药化学和材料科学的一个主题.

结构式图片

欧盟法规

ECHA物质ECHA物质C&L通报REACH预注册

上下游产品

2,2'-(o-phenyldioxy)-4,5-benzo-1,3,2-dioxaphospholane-4',5'-benzo-1',3',2'-dioxaphospholane benzene-1,2-diol 2-(N-butyl-N-isobutenylamino)-4,5-benzo-1,3,2-dioxaphospholane 2-phenoxy-1,3,2-benzodioxaphosphole 2-(4-nitro-phenoxy)-benzo[1,3,2]dioxaphosphole N-benzyloxycarbonyl-L-phenylalanine hydrazide o-methoxyphenyl-o-phenylene phosphite ethyl [(2S)-2-(benzyloxycarbonylamino)-3-phenylpropanoylamino]acetate

合成工艺路线路线简述

    📜邻苯二酚置于硅酸四乙酯,三乙胺,三氯化磷体系中,化学反应生成A-丙烯酸氯甲酯
    参考文献:高价硅中心介导的高产率合成环状亚磷酸酯,磷酸盐,亚硫酸盐和邻苯二酚和乙二醇的硫酸盐
    标题:高价硅中心介导的高产率合成环状亚磷酸酯,磷酸盐,亚硫酸盐和邻苯二酚和乙二醇的硫酸盐
    摘要:均三(邻苯二酚)硅酸盐m 2 [si(oc 6 H 4 O 2)3 ] M = Na,Et 3 Nh和甘醇硅酸盐k 2 [si 2(o 2 C 2 H 4)5 ]与pcl 3一起,Pocl 3,Socl 2和so 2 Cl 2放热进行,并容易分离出相应的邻苯二酚/乙二醇环状衍生物(1-8)以高收率,证明了高价硅中心在合成中的优点.(et 3 Nh)2 [si(oc 6 H 4 O 2)3 ]提供接近定量的转化率.
    Doi:10.1016/s0040-4039(97)01020-4

    海关参考信息

    专利信息


    专利号:US-12291489-B2
    优先权日:2016-07-01
    标 题 :Synthesis of nanocomposites and their use in enhancing plant nutrition
    发明人:BISWAS PRATIM; RALIYA RAMESH
    权利人:BISWAS PRATIM; RALIYA RAMESH; WASHINGTON UNIVERSITY ST LOUIS
    摘要:The present disclosure is related to the development of improved fertilizer for precision and sustainable agriculture. A method was developed wherein efficient NPK nanocomposite for plant nutrition was synthesized in a single step using aerosol science and technology concepts. Further a formulation was prepared by addition of ZnO, TiO 2 and other nanoparticles to the NPK nanocomposite. Also, an aerosol based foliar application technique was developed for the precise delivery of nanoparticles to the plants.

    专利号:US-4341706-A
    优先权日:1980-10-10
    标题 :Process for the preparation of carbapenem antibiotics
    发明人:CHRISTENSEN BURTON G; SHIH DAVID H
    权利人:MERCK & CO INC
    摘要:Disclosed is a process for the synthesis of carbapenem antibiotics I and their pharmaceutically acceptable salts and esters from 1: wherein: R7, R6, R1, R2 and R8 are selected from hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl, spirocycloalkyl, cycloalkylalkyl, alkylcycloalkyl, aryl, aralkyl, aralkenyl, aralkynyl, heteroalkyl, heteroaralkyl, heterocyclyl and heterocyclyalkyl.

    专利号:US-4460507-A
    优先权日:1980-10-10
    标题:Process for the preparation of thienamycin
    发明人:SHIH DAVID H
    权利人:MERCK & CO INC
    摘要:Disclosed is a process for the total synthesis of thienamycin from descysteaminylthienamycin 1 ##STR1## via thienamycin sulfoxide 4: ##STR2## R 3 , R°, R' are blocking groups.

    专利号:WO-2023060929-A1
    优先权日:2021-10-15
    标题 :Application of polydentate phosphite ligand in catalytic synthesis of adiponitrile

    专利号:EP-4190769-A1
    优先权日:2021-10-15
    标题 :Application of polydentate phosphite ligand in catalytic synthesis of adiponitrile

    专利号:US-2722526-A
    优先权日:1952-09-24
    标题:Trialkylphosphites as acid acceptors in the synthesis of amides
    发明人:WASHINGTON ANDERSON GEORGE; WILLIAM YOUNG RICHARD
    权利人:AMERICAN CYANAMID CO

    供应商参考报价(招募中)

    品牌试剂参考报价(招募中)

    📌 第三方产品分析报告

    ✅ COA系统入驻 | 共享模式

    合成参考文献


    摘要:Pajkert, R.; Röschenthaler, G.-V., Science of Synthesis Knowledge Updates, (2022) 1, 366.
    摘要:Zefirov, N. S.; Matveeva, E. D.; Shuvalov, M. V., Science of Synthesis: Multicomponent Reactions, (2013) 1, 280.
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