CAS: 147065-06-3; H-D-Phe(4-No2)-Oh.Hcl

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2-acetylamino-2-(4-nitrobenzyl)malonic acid diethyl ester ethyl 2-acetylamino-2-cyano-3-(4-nitrophenyl)propanoate 1-bromomethyl-4-nitro-benzene N-Benzoyl-p-nitro-D-phenylalanine α-(2-Naphthylsulfonylglycyl)-4-nitro-phenylalaninpiperididNα-(2-Naphthylsulfonylglycyl)-4-nitro-phenylalaninpiperidid α-(2-Naphthylsulfonylglycyl)-4-amino-phenylalaninpiperididhydr°ChloridNα-(2-Naphthylsulfonylglycyl)-4-amino-phenylalaninpiperididhydr°Chlorid α-(2-Naphthylsulfonylglycyl)-4-amino-phenylalaninpiperididNα-(2-Naphthylsulfonylglycyl)-4-amino-phenylalaninpiperidid 2-acetylamino-3-(4-nitro-phenyl)-propionic acid methyl ester

📜(Z)-2-苯酰胺-3-(4-硝基苯基)丙烯酸置于盐酸,(-)-(R)-Cationic Rhodium Complex Of "Propharos",氢气体系中,用 甲醇 用作溶剂,25.0 °C,100.0 Kpa 条件下,反应 7.0H,反应生成4-硝基-D-苯丙氨酸盐酸盐
参考文献:Unusual Amino Acids Iii. Asymmetric Synthesis Of 3-Arylalanines
标题:Unusual Amino Acids Iii. Asymmetric Synthesis Of 3-Arylalanines
摘要:21 (Z)-Alpha-N-Benzoylamino-Beta-Arylacrylic Acids And Their Esters Were Prepared By Known Procedures And Hydrogenated To The Corresponding Optically Active Alpha-Benzoyl-Beta-Arylalanine Derivatives With Optical Yields In The Range Of 82-95% Ee Using The Cationic Rhodium Complex Of ''Propraphos'' As The Chiral Catalyst No Electronical Influences Of The Substituents At The Aryl Moiety On The Enantioselectivity Were Observed But A Sterical One,Proved By X-Ray Crystallographic Analysis And Computer-Aided Modellings. Deacylation Of The Hydrogenated Spezies Produced The Hydrochlorides Of The 3-Arylalanines Attended By A Partial Racemisation In This Case The Hydrogenation Of Urethane Type Protected Dehydroaminoacid Derivatives Seems To Be The Alternative.
Doi:10.1016/s0957-4166(00)86017-6