CAS: 90761-62-9; (S)-2-(3,5-Dinitrobenzamido)-2-Phenylacetic Acid

该化合物是属于氨基酸衍生物类的化学化合物,具有与甘油主干柱的甲型碳相连的一组苯基,由于存在3,5-dinitrobenzoyl mothis的进一步修改,该化合物的特点是独特的功能组,包括有助于其再活性和在各种化学反应中潜在应用的硝基化合物.dinitrobenzyl组的存在增强了其电子哲学特性,使其在合成有机化学中有用,特别是在制药和农用化学品开发中.此外,该化合物由于其结构特征可能具有具体的生物活动,可能对医药化学感兴趣.其溶性,稳定性和再活性可能因溶剂和条件而不同,因此有必要将这些因素纳入各种实际应用.

结构式图片

上下游产品

CAS号2935-35-5 (|S|)-(+)-α-苯甘氨酸 | CAS号99-33-2 3,5-二硝基苯甲酰氯 | CAS号611-73-4 苯甲酰甲酸 | CAS号74958-71-7 N-(3,5-二硝基苯甲酰基)... | CAS号2835-06-5 DL-苯甘氨酸

合成工艺路线路线简述

  • 合成目标产物 (S)-(+)-N-(3,5-Dinitrobenzoyl)-Alpha-Phenylglycine 主要起始原料 Benzoylformic Acid
  • 2935-35-5 + 99-33-2 = 90761-62-9
    反应条件:1.1 Solvents: Tetrahydrofuran; 1 W,Rt
    标题:Chiral Permselectivity In Nanoporous Opal Films Surface-Modified With Chiral Selector Moieties
    作者:Cichelli,Julie; Zharov,Ilya
    参考文献:Journal Of Materials Chemistry 日期:2007 卷标:17(19) 页码:1870-1875]

    2935-35-5 + 99-33-2 = 90761-62-9
    反应条件:1.1 Solvents: Tetrahydrofuran
    标题:A-(Modified B6)-B-[ω-Amino(Ethylamino)]-β-Cyclodextrin As An Artificial B6 Enzyme For Chiral Aminotransfer Reaction
    作者:Tabushi,Iwao; Kuroda,Yasuhisa; Yamada,Masahiko; Higashimura,Hideyuki; Breslow,Ronald
    参考文献:Journal Of The American Chemical Society 日期:1985 卷标:107(19) 页码:5545-6
📜苯甲酰甲酸置于a-(Modified B6)-B-<ω-Amino(Ethylamino)>-β-Cyclodextrin体系中,用 四氢呋喃,水 作为反应溶剂,化学反应 5.0H,反应生成 N-(3,5-二硝基苯甲酰)-L-α-苯基甘氨酸
参考文献:A-(Modified B6)-B-[.Omega.-Amino(Ethylamino)]-.Beta.-Cyclodextrin As An Artificial B6 Enzyme For Chiral Aminotransfer Reaction
标题:A-(Modified B6)-B-[.Omega.-Amino(Ethylamino)]-.Beta.-Cyclodextrin As An Artificial B6 Enzyme For Chiral Aminotransfer Reaction
摘要:
DOI:10.1021/ja00305A048

海关参考信息

专利信息


专利号:US-8981121-B2
优先权日:2010-06-25
标 题 :Process for the preparation of nitrogen substituted aminotetralins derivatives
发明人:ATES CELAL; SCHULE ARNAUD; PALACIO MAGALI; DEUTSCH PAUL; VASSELIN DAVID; CARLY NICOLAS; PHADTARE GANESH; YERANDE SWAPNIL; DELATINNE JEAN-PIERRE; ESCUDERO HERNANDEZ MARIA LUISA; PINILLA VERONIQUE
权利人:ATES CELAL; SCHULE ARNAUD; PALACIO MAGALI; DEUTSCH PAUL; VASSELIN DAVID; CARLY NICOLAS; PHADTARE GANESH; YERANDE SWAPNIL; DELATINNE JEAN-PIERRE; ESCUDERO HERNANDEZ MARIA LUISA; PINILLA VERONIQUE; UCB PHARMA GMBH
摘要:The present invention provides an alternative synthesis of N-substituted aminotetralines comprising resolution of N-substituted aminotetralins of formula (II), wherein R 1 , R 2 and R 3 are as defined for compound of formula (I).

专利号:US-7420070-B2
优先权日:2000-12-28
标 题:Process for preparing optically active 2,3-dihydrobenzofuran compounds
发明人:AOKI ISAO; ADACHI MARI; TAWADA HIROYUKI; YAMASHITA MAKOTO; SERA MISAYO
权利人:TAKODA PHARMACEUTICAL COMPANY
摘要:A process for preparing optically active 2,3-dihydrobenzofuran compounds which comprises subjecting a 2,3-dihydrobenzofuran compound represented by the general formula or a salt thereof to optical resolution with an optically active acid compound: n n[wherein R 1 and R 2 are each hydrogen or an optionally substituted hydrocarbon group; R 3 is an optionally substituted aromatic group; and C is a benzene ring which may further have a substituent in addition to the amino group]. The process enables industrially advantageous production of intermediates for the synthesis of optically active 2,3-dihydrobenzofuran compounds useful as preventive and/or therapeutic drugs for neurodegenerative diseases and so on.

专利号:US-9217012-B2
优先权日:2009-04-08
标题 :Inhibitors of protein tyrosine phosphatases
发明人:ZHANG ZHONG-YIN; ZHANG SHENG
权利人:ZHANG ZHONG-YIN; ZHANG SHENG; UNIV INDIANA RES & TECH CORP
摘要:Disclosed herein are compounds that selectively inhibit members of the PTP family of enzymes. Synthesized compounds demonstrated selective inhibition of TC-PTP. Also provided are methods of using the compounds and formulations containing the compounds. Also described is a fluorescence-tagged combinatorial library synthesis and screening method. And methods of using these compounds to effect enzyme activity both in cells and in vitro as well as method of using these compounds to treat diseases in human and animals.

专利号:EP-0965591-A1
优先权日:1991-06-21
标 题 :(s)-3-methyl-1-(2-piperidino-phenyl)-1-butylamine, its salts, synthesis and use in the long term therapy of diabetes mellitus

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📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1021/ja058004x
摘要:Chen Z, Yang Y, Werner S, Wipf P, Weber SG. A screening method for chiral selectors that does not require covalent attachment. J Am Chem Soc. 2006 Feb 22;128(7):2208–9.
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