CAS: 89131-09-9; (E)-((4-((4-(Dimethylamino)Phenyl)Diazenyl)Phenyl)Sulfonyl)-L-Proline

该化合物是一种化学化合物,其结构特征是作为氨基酸,氨基酸的一种衍生物,以其在生化研究中的应用而著称,特别是在对丙化物合成和蛋白相互作用的研究中;该化合物的特性是Dabsylmolline组,该组是提高其荧光特性的全氟辛烷磺酸,使其在色谱和荧光光谱学等分析技术中有用;Dabsylproline通常用作氨基酸和的标签剂,以便追踪和量化这些生物分子,在各种实验环境中,其有机溶剂中的溶性以及各种条件下的稳定性进一步增进了其在实验室应用中的效用;此外,该化合物能够与氨基元素形成稳定的共生,其毒性相对较低,因此它成为生物化学和分子生物学领域研究人员的有利选择.总的来说,Dabsyproline是蛋白质结构和功能探索中的宝贵工具.

英文名称(E)-((4-((4-(Dimethylamino)Phenyl)Diazenyl)Phenyl)Sulfonyl)-L-Proline
中文名称丹磺酰-L-脯氨酸
IUPAC名称(E)-((4-((4-(dimethylamino)phenyl)diazenyl)phenyl)sulfonyl)-L-proline
其它别名Dabsyl-L-Proline; 1-(4-{(E)-[4-(Dimethylamino)Phenyl]Diazenyl}Benzene-1-Sulfonyl)-L-Proline; (S,E)-1-(4-((4-(Dimethylamino)Phenyl)Diazenyl)Phenylsulfonyl)Pyrrolidine-2-Carboxylic Acid; 4-Dimethylaminoazobenzene-4'-Sulfonyl-L-Proline
CAS编号89131-09-9
MFCD编号:MFCD00059729
分子式:C19H22N4O4S分子量:402.48
产品CID: 1912498
产品分类生物化工 → 氨基酸及其衍生物 → 脯氨酸类衍生物

相似结构搜索
InChIKey: IIHLDMYXACDQGQ-MKSIGINJSA-N
InChI=1S/C19H22N4O4S/c1-22(2)16-9-5-14(6-10-16)20-21-15-7-11-17(12-8-15)28(26,27)23-13-3-4-18(23)19(24)25/h5-12,18H,3-4,13H2,1-2H3,(H,24,25)/b21-20+/t18-/m0/s1
计算化学: 氢键受体数8.0氢键供体数1.0可旋转键数6.0

MSDS等安全信息

警示词Warning
危险描述H302-H315-H319-H335-
防范说明P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P330-P362-P403+P233-P501-

上下游产品

CAS号56512-49-3 4-二甲胺基苯基偶氮苯磺酰氯 | CAS号147-85-3 脯氨酸

合成工艺路线路线简述

56512-49-3 + 147-85-3 = 89131-09-9 [标题:Reaction Conditions
标题:Operationally Safe Amino Acid Analysis With The Dabsyl Chloride System
作者:Nieder,Michael; Hughes,Graham J.; Frutiger,Severine; Grom,Edgar
参考文献:Laborpraxis 日期:1990 卷标:14 页码:30-1

📜4-二甲胺基苯基偶氮苯磺酰氯,L-脯氨酸置于碳酸氢钠体系中,用乙腈作为反应溶剂,化学反应生成丹磺酰-L-脯氨酸
参考文献:Trichoderins,Novel Aminolipopeptides From A Marine Sponge-Derived Trichoderma Sp.,Are Active Against Dormant Mycobacteria
标题:Trichoderins,Novel Aminolipopeptides From A Marine Sponge-Derived Trichoderma Sp.,Are Active Against Dormant Mycobacteria
摘要:Three New Aminolipopeptides,Designated Trichoderins A (1),A1 (2),And B (3),Were Isolated From A Culture Of Marine Sponge-Derived Fungus Of Trichoderma Sp. As Anti-Mycobacterial Substances With Activity Against Active And Dormant Bacilli. The Chemical Structures Of Trichoderins Were Determined On The Basis Of Spectroscopic Study. Trichoderins Showed Potent Anti-Mycobacterial Activity Against Mycobacterium Smegmatis,Mycobacterium Bovis Bcg,And Mycobacterium Tuberculosis H37Rv Under Standard Aerobic Growth Conditions As Well As Dormancy-Inducing Hypoxic Conditions,With Mic Values In The Range Of 0.02-2.0 Mu G/ml. (C) 2010 Elsevier Ltd. All Rights Reserved.
DOI:10.1016/j.Bmcl.2010.04.100