CAS: 64872-77-1; 1-(4-(4-Chlorophenyl)-2-((2,6-Dichlorophenyl)Thio)Butyl)-1H-Imidazole Nitrate

布康唑置于硝酸体系中,化学反应生成 硝酸布康唑
参考文献:一种硝酸布康唑的制备方法
标题:一种硝酸布康唑的制备方法
摘要:本发明公开了一种硝酸布康唑的制备方法.以4‑氯苄基氯为起始原料合成1‑氯‑4‑(4‑氯苯基)‑2‑丁醇,再合成1‑(4‑(4‑氯苯基)‑2‑羟基‑丁基)咪唑,然后再合成1‑(4‑(4‑氯苯基)‑2‑氯‑丁基)咪唑,将1‑(4‑(4‑氯苯基)‑2‑氯‑丁基)咪唑,2,6‑二氯苯硫酚,碳酸钾加入到丙酮中,加热回流,反应完成后加入水和乙酸乙酯,分液,乙酸乙酯相依次用饱和碳酸钾和饱和食盐水洗涤,无水硫酸镁干燥,去除硫酸镁后,冰浴下滴加65%的硝酸,至无沉淀产生,过滤收集固体,用无水乙醇重结晶,得白色晶体,即硝酸布康唑.本发明的一种硝酸布康唑的制备方法,工艺简单,收率高,成本低,得到的产品纯度高.

专利信息

专利号:US-8361516-B2
优先权日:2006-08-03
标 题:Composition comprising sarsasapogenin
发明人：LINTNER KARL; MAS CHAMBERLIN CLAIRE
权利人:SEDERMA SA; LINTNER KARL; MAS CHAMBERLIN CLAIRE
摘要:The présent invention relates to a composition comprising sarsasapogenin or a plant extract containing it in order to improve the gêneral state of the skin and in particular to improve and/or embellish any part of the body showing a déficit in lipids. More particularly, the invention is directed to a cosmetic method to improve the figure, comprising the step of topically applying to the skin a cosmetic or dermopharmaceutical composition comprising sarsasapogenin to favour the expansion and/or the formation of the subcutaneous adipose tissue, and/or to favour the lipid synthesis in the epidermis.

专利号:US-2014315720-A1
优先权日:2012-10-24
标 题 :Polysaccharide ester microspheres and methods and articles relating thereto
发明人：FALLON DENIS G; GARRETT THOMAS S; KIZER LAWTON E; ZAZZARA KAREN L; COMBS MICHAEL T; JOHNSON RICHARD K; DEHART GARY
权利人:CELANESE ACETATE LLC
摘要:A method for producing a polysaccharide ester microsphere may include forming a polysaccharide ester product from a polysaccharide synthesis, wherein the polysaccharide ester product comprises a polysaccharide ester and a solvent; diluting the polysaccharide ester product, thereby yielding a polysaccharide ester dope; and forming a plurality of polysaccharide ester microspheres from the polysaccharide ester dope. Suitable polysaccharides may include, but are not limited to, starch, cellulose, hemicellulose, algenates, chitosan, and any combination thereof. Esters thereof may be organic esters (e.g., acetate and the like), inorganic esters (e.g., sulfonates and the like), or combinations thereof. Further, the solids conent of the polysaccharide ester dope, in some instances, may be greater than about 16 wt %.

专利号:CN-105175341-A
优先权日:2015-10-09
标题 :A kind of method of industrialized synthesis butoconazole nitrate intermediate

专利号:CN-105198817-A
优先权日:2015-10-09
标 题 :A kind of method of industrialized synthesis butoconazole nitrate intermediate

专利号:CN-105175341-B
优先权日:2015-10-09
标 题:A kind of method for industrializing nitric acid synthesis butoconazole intermediate

专利号:CN-105198817-B
优先权日:2015-10-09
标题 :A kind of method for industrializing nitric acid synthesis butoconazole intermediate