CAS: 520-32-1; 5,7-Dihydroxy-2-(4-Hydroxy-3,5-Dimethoxyphenyl)-4H-Chromen-4-One

该化合物是大米和其他谷物中,是一种氟化素化合物,被归类为氟化素,这是一种具有特定化学结构特征的氟化素,包括铬质骨干;三氯酚显示出抗氧化剂特性,有助于其潜在的健康惠益,包括防炎和抗癌效应;还因其在植物色素和紫外线保护方面的作用而闻名;就溶解性而言,三氯酚一般在有机溶剂中溶解,但在水中溶解性有限;其分子结构包括增加其活性以及与其他生物分子互动的氢化物组;三氯酚由于其潜在的健康促进特性,已引起对食品科学和营养的兴趣,使其成为药理学和功能食品领域研究的课题;

结构式图片

上下游产品

CAS号480-66-0 2',4',6'-三羟基苯乙酮 | CAS号884-35-5 丁香酸甲酯 | CAS号134178-07-7 methyl 4-[(tert... | CAS号6318-20-3 乙酰丁香酸 | CAS号39657-47-1 Benzoyl chlorid... | CAS号108956-90-7 2',4'-O-bis(ter... | CAS号18103-42-9 5,7-二羟基-3',4',5... | CAS号86978-66-7 anhydride of 4-...

合成工艺路线路线简述

  • 合成目标产物 Tricin 主要起始原料 Methyl Syringate
  • (文献来源)合成步骤主要原料 Methyl Syringate
📜苜蓿素-7-O-葡萄糖苷置于盐酸体系中,用 甲醇,水 作为反应溶剂,化学反应 4.0H,反应生成 苜蓿素
参考文献:异源多倍体 Spartina Anglica 中的类黄酮模式遗传--与亲本 S. Maritima 和 S. Alterniflora 的比较
标题:异源多倍体 Spartina Anglica 中的类黄酮模式遗传--与亲本 S. Maritima 和 S. Alterniflora 的比较
摘要:入侵物种 Spartina Anglica 起源于欧洲,由非洲-欧洲物种 S. Maritima(本地,父系祖先)和引入的北美互花米草(入侵,母系祖先)杂交而成.从植物组织中制备含水甲醇提取物,用于三个物种之间的化学分类比较,并确定 S. Anglica 中的酚类遗传.在 S. Anglica 和 S. Alterniflora 的地上组织中共检测到 20 种酚类化合物,但在 S. Maritima 中仅检测到 7 种酚类化合物.它们从各自的粗提物中分离出来,并根据光谱数据分析和化学证据确定了它们的结构.它们都属于黄酮类,其中 13 种被鉴定为 C-糖类黄酮,7 种被鉴定为 O-糖类黄酮.所有这些产品均为首次从s. Anglica 中检测到,其中14 种为首次从s. Alterniflora 中检测到,其中3 种为首次从s. Maritima 中检测到.通过定量 HPLC 测定三种物质中的
DOI:10.1016/j.Phytochem.2020.112312

海关参考信息

专利信息


专利号:WO-2020032913-A1
优先权日:2018-08-04
标题:Process for synthesis of oroxylin a
发明人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA
摘要:Disclosed is a novel, simple, scalable and environment friendly process for the synthesis of Oroxylin A from Baicalin. Baicalm is esterified to obtain a methyl ester which is further selectively methylated to provide Oroxylin A gluciironide methyl ester which on de- glycosylation results in the formation of Oroxylin A.

专利号:US-2009221568-A1
优先权日:2005-11-04
标题:Synthesis of Inhibitors of FtsZ
发明人:SHAW JARED; URGAONKAR SAMEER; RAYCHAUDHURI DEBABRATA; LA PIERRE HENRY
权利人:SHAW JARED; URGAONKAR SAMEER; RAYCHAUDHURI DEBABRATA; LA PIERRE HENRY
摘要:FtsZ, the bacterial analog of tubulin, is a promising new target for developing new antibiotics. It has been shown that polyphenols inhibit the GTPase activity of FtsZ, thereby inhibiting Z-ring formation during mitosis. The present invention provides novel polyphenols compounds, which can be accessed by the synthesis of dichamametin and 2′″-hydroxy-5″-benzylisouvarinol-B as described herein. These novel compounds are useful in treating infections, particularly infections caused by gram-positive organisms. Methods of preparing the inventive compounds are also provided. The compounds are prepared by the benzylation of pinocembrin or chrysin core structure. Pharmaceutical compositions and method of using the compounds to treat disease are also provided. These compounds may be screened for antimicrobial activity as well as other biological activities such as anti-neoplastic, anti-inflammatory, immunosuppressive, and cytotoxic activity.

专利号:WO-2025081225-A1
优先权日:2023-10-17
标 题 :Synthesis of polyphenols
发明人:TURLAND CADE LACHLAN; GROLMAN DAVID; BEHRENDORFF JAMES BRUCE YARNTON HAYCOCK; MORADI SHAYLI VARASTEH; THOMSON RAINE ELIZABETH STURT
权利人:Delica Therapeutics Pty Ltd
摘要:The present disclosure relates to polyphenols, including flavonoids, flavones and cannflavins, and methods of synthesising polyphenols. The present disclosure provides methods, enzymes and compositions that may be useful in the synthesis of polyphenols.

专利号:US-5262312-A
优先权日:1990-04-25
标 题:Process for the glycosidase-catalyzed synthesis of glyco conjugates
发明人:HOLLA WOLFGANG; SCHUDOK MANFRED
权利人:HOECHST AG
摘要:It has been possible to show for a first time with the process according to the invention that the synthesis of glyco conjugates is possible by direct linkage of sugars with serine, serine derivatives and serine peptides with the aid of glucosidases.

专利号:EP-2017267-A1
优先权日:2007-07-16
标 题:Synthesis of statins
发明人:KOPITAR GREGOR; MRAK PETER; OSLAJ MATEJ
权利人:LEK PHARMACEUTICALS
摘要:The process for synthesis of statins is presented where the intermediate intermediate (4 R ,6 S )-6-(dialkoxymethyl)tetrahydro-2 H -pyran-2,4-diol which already possesses the desired stereochemistry corresponding to final statin is prepared by an aldolaze.

专利号:US-10407401-B1
优先权日:2018-08-04
标题 :Process for synthesis of Oroxylin A
发明人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA
权利人:MAJEED MUHAMMED; NAGABHUSHANAM KALYANAM; RAMANUJAM RAJENDRAN; HEMANTHA HOSAHALLI PRABHAKARA; SAMI LABS LTD
摘要:Disclosed is a novel, simple, scalable and environment friendly process for the synthesis of Oroxylin A from Baicalin. Baicalin is esterified to obtain a methyl ester which is further selectively methylated to provide Oroxylin A glucuronide methyl ester which on de-glycosylation results in the formation of Oroxylin A.

供应商参考报价(招募中)

品牌试剂参考报价(招募中)

📌 第三方产品分析报告

✅ COA系统入驻 | 共享模式

合成参考文献


参考文献:10.1016/j.antiviral.2011.06.014
摘要:Akuzawa K, Yamada R, Li Z, Li Y, Sadanari H, Matsubara K, Watanabe K, Koketsu M, Tuchida Y, Murayama T. Inhibitory effects of tricin derivative from Sasa albo-marginata on replication of human cytomegalovirus. Antiviral Res. 2011 Sep;91(3):296–303. doi: 10.1016/j.antiviral.2011.06.014.
摘要:Matsuta T, Sakagami H, Satoh K, Kanamoto T, Terakubo S, Nakashima H, Kitajima M, Oizumi H, Oizumi T. Biological activity of luteolin glycosides and tricin from Sasa senanensis Rehder. In Vivo. 2011 Sep;25(5):757–62.
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