CAS: 517-60-2; Mellitic Acid

该化合物是石墨或煤氧化后产生的六丙基有机化合物,其结构结构有六个碳苯基组,在苯环周围对称排列,具有高酸性和铬化特性,极地溶剂的稳定性和溶性显著,使其在协调化学以形成金属-有机框架和作为先进材料的前体方面有用.

结构式图片

相似化合物

1585-40-6 569-51-7 528-44-9

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合成工艺路线路线简述

  • 合成目标产物 Mellitic Acid 主要起始原料 1,2,3,4,5,6-Cyclohexanehexacarboxylic Acid
  • (文献来源)合成步骤主要原料 1,2,3,4,5,6-Cyclohexanehexacarboxylic Acid
[2,3,4,5,6-五(羟甲基)苯基]甲醇置于potassium Permanganate体系中,化学反应生成 苯六甲酸
参考文献:Laparoscopic Transperitoneal Hernia Repair Of Incarcerated Hernias: Is It Feasible
标题:Laparoscopic Transperitoneal Hernia Repair Of Incarcerated Hernias: Is It Feasible
摘要:Background: Laparoscopic Transperitoneal Hernia Repair (Tapp) Has Proved Its Efficiency In Elective Surgery. However,Tapp Results With Incarcerated Hernias Still Are Unknown.Methods: Data From A Prospective Study Were Evaluated With Regard To Tapp Repair For Both Chronically And Acutely Incarcerated Hernias.Results: During A 6-Year Period,220 Incarcerated Hernias Were Repaired (194 Via Tapp). The Median Operation Time For Tapp Was 55 Min. An Accompanying Resection Therapy Became Necessary For Only Four Of The Emergency Cases (11.1%) And Two Of The Chronically Incarcerated Cases (1.3%) In The Tapp Group. Postoperative Morbidity Was 2.8% In The Emergency Group And 3.8% In The Chronically Incarcerated Group,Which Does Not Differ From The Rate For Tapp Used On Reducible Hernias. One Recurrence Was Found 26 Months After Tapp Reconstruction (0.5%).Conclusion: Laparoscopic Inguinal. Hernia Repair (Tapp) Represents An Efficient Therapeutic Concept In The Treatment Of Both Chronically And Acutely Incarcerated Inguinal Hernias.
DOI:10.1007/s004640090073

海关参考信息

专利信息


专利号:US-2023294064-A1
优先权日:2015-12-28
标 题:Substrates, systems, and methods for nucleic acid array synthesis
发明人:RAJASEKARAN JOHN J
权利人:VIBRANT HOLDINGS LLC
摘要:Disclosed herein are formulations, substrates, and arrays for the synthesis of PNA chains and PNA-DNA chimera on microarrays. In some embodiments, the formulations include a photo-protective compound that shields any PNA monomers, PNA polymers, or PNA-DNA chimera already attached to a microarray from radiation exposure during the synthesis of the PNA or PNA-DNA chains. In some embodiments, substrates and arrays comprise a porous or a planar layer for synthesis and attachment of PNA or DNA monomers, or PNA or PNA-DNA polymers. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of PNA monomers or PNA polymers to a microarray substrate.

专利号:US-12251674-B2
优先权日:2012-11-14
标 题:Substrates, systems, and methods for array synthesis and biomolecular analysis
发明人:RAJASEKARAN JOHN J; JAYARAMAN VASANTH; WANG TIANHAO; BEI KANG; KRISHNAMURTHY HARI KRISHNAN; VEDANTHAM PUNITHA
权利人:VIBRANT HOLDINGS LLC
摘要:Disclosed herein are formulations, substrates, and arrays. In certain embodiments, substrates and arrays comprise a porous layer for synthesis and attachment of polymers or biomolecules. Also disclosed herein are methods for manufacturing and using the formulations, substrates, and arrays, including porous arrays. Also disclosed herein are formulations and methods for one-step coupling, e.g., for synthesis of peptides in an N→C orientation. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.

专利号:US-11661658-B2
优先权日:2018-06-15
标题:Electrochemical synthesis of ammonia
发明人:HERTZBERG BENJAMIN JOSEPH
权利人:HERTZBERG BENJAMIN JOSEPH
摘要:Systems and methods for electrochemical ammonia synthesis comprise electrolytes which have greater efficiency than water, thus leading to cost reductions; and/or cathode catalysts which have lower costs and higher efficiencies in comparison to the iron/nickel catalysts noted above. The electrolyte may be composed primarily of a combination of non-aqueous hydrogen bond donors and acceptors, with high nitrogen solubility and high conductivity. The cathode catalyst may be composed of either a manganese-doped oxide or carbonate material or a two-dimensional carbide or nitride material.

专利号:US-9487399-B2
优先权日:2010-08-17
标题 :Method for the synthesis of metallic nano products
发明人:GHANAVI JALALEDIN; MOSTAFAVI MEHRNAZ; GHANAVI ZOHRE
权利人:GHANAVI JALALEDIN; MOSTAFAVI MEHRNAZ; GHANAVI ZOHRE
摘要:The embodiments herein provide a method of synthesis for metallic nano-products such as metallic nano-antennas, metallic nano-rods, metallic nano-wires, metallic nano-prolate spheroids and metallic nano-oblate spheroids using saturated and unsaturated carboxylic acids. The method involves preparing a reaction mixture by mixing a polar protic solvent, a polar aprotic solvent or a non-polar solvent, a saturated fatty acid or an unsaturated fatty acid and a metallic salt. Then a mixture of reducing agents is prepared by mixing a polar protic solvent, a polar aprotic solvent or a non-polar solvent and a saturated fatty acid or an unsaturated fatty acid. The reaction mixture and the mixture of reducing agents are combined and heated solvo-thermally for a pre-determined period of time at a pre-determined temperature.

专利号:US-10577391-B2
优先权日:2014-02-21
标题 :Selective photoactivation of amino acids for single step peptide coupling
发明人:JAYARAMAN VASANTH
权利人:VIBRANT HOLDINGS LLC
摘要:Disclosed herein are formulations, substrates, and arrays for amino acid and peptide synthesis on microarrays. In certain embodiments, methods for manufacturing and using the formulations, substrates, and arrays including one-step coupling, e.g., for synthesis of peptides in a C→N orientation are disclosed. In some embodiments, disclosed herein are formulations and methods for high efficiency coupling of biomolecules to a substrate.

专利号:US-5214118-A
优先权日:1990-10-05
标 题:Process for synthesis of polyestercarbonate-siloxane copolymers
发明人:HAWKINS CHRISTOPHER M; ROSENQUIST NILES R
权利人:GEN ELECTRIC
摘要:A process for synthesizing polyestercarbonate-siloxane copolymers which have a smaller concentration of low molecular weight species and greater thermal stability has been described. Essentially the process includes adding the comonomer, diacid chloride siloxane, after approximately 1/3 of the phosgene has been added, in a conventional interfacial copolymerization, (as opposed to addition at the beginning of the polymerization).
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✅ COA系统入驻 | 共享模式

主要参考文献

[参考文献]: A Avdeef, Et Al. Ph-Metric Log P. Ii: Refinement Of Partition Coefficients And Ionization Constants Of Multiprotic Substances. J Pharm Sci. 1993 Feb;82(2):183-90.
[参考文献]: F Bonneaux, Et Al. Hemoglobin-Dialdehyde Dextran Conjugates: Improvement Of Their Oxygen-Binding Properties With Anionic Groups. J Protein Chem. 1996 Jul;15(5):461-5.
[参考文献]: F Stalport, Et Al. Investigating The Photostability Of Carboxylic Acids Exposed To Mars Surface Ultraviolet Radiation Conditions. Astrobiology. 2009 Jul-Aug;9(6):543-9.
[参考文献]: Fabien Stalport, Et Al. Uvolution, A Photochemistry Experiment In Low Earth Orbit: Investigation Of The Photostability Of Carboxylic Acids Exposed To Mars Surface Uv Radiation Conditions. Astrobiology. 2010 May;10(4):449-61.
[参考文献]: Hnin Thanda Aung, Et Al. Benzenepolycarboxylic Acids With Potential Anti-Hemorrhagic Properties And Structure-Activity Relationships. Bioorg Med Chem. 2011 Dec 1;19(23):7000-2.

合成参考文献


摘要:A. G. Warner and E. P. Serjeant, unpublished results.
参考文献:10.1007/s10059-011-2254-1
摘要:Yu WS, Jeong SJ, Kim JH, Lee HJ, Song HS, Kim MS, Ko E, Lee HJ, Khil JH, Jang HJ, Kim YC, Bae H, Chen CY, Kim SH. The genome-wide expression profile of 1,2,3,4,6-penta-O-galloyl-β-D-glucose-treated MDA-MB-231 breast cancer cells: molecular target on cancer metabolism. Mol Cells. 2011 Aug;32(2):123–32.
参考文献:10.1007/bf01891986
摘要:Sacco D, Dellacherie E, Prouchayret F. Effect of covalent labeling of dextran-benzenehexacarboxylate on hemoglobin. J Protein Chem. 1994 Jan;13(1):1–8. doi: 10.1007/bf01891986.
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