CAS: 508-71-4; Rosenonolactone

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7β,10β,19-Trihydroxyros-15-eneRosenololactone Rosan-16-saeure

合成工艺路线路线简述

    📜7β,10β,19-Trihydroxyros-15-Ene 以 乙醇 作为反应溶剂,化学反应 168.0H,以100 Mg的收率获得产物玫瑰菌素
    参考文献:Biosynthetically Directed Microbiological Transformations With The Fungus Trichothecium Roseum
    标题:Biosynthetically Directed Microbiological Transformations With The Fungus Trichothecium Roseum
    摘要:
    DOI:10.1016/0031-9422(90)85335-D

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    主要参考文献


    1: Wang SR, Zhang L, Chen HP, Li ZH, Dong ZJ, Wei K, Liu JK. Four new spiroaxane sesquiterpenes and one new rosenonolactone derivative from cultures of Basidiomycete Trametes versicolor. Fitoterapia. 2015 Sep;105:127-31. doi: 10.1016/j.fitote.2015.06.017. Epub 2015 Jun 30. doi: 10.1007/BF03192220.
    5: Schabort JC, Roberts HA. Effect of versicolorin C, rosenonolactone and cyclopiazonic acid on bovine pancreas deoxyibonuclease. Biochem Pharmacol. 1971 Jan;20(1):243-6. doi: 10.3390/molecules13102474. doi: 10.1007/BF03192135. doi: 10.1007/s12275-010-0173-z. Epub 2011 Jan 9. German.

    合成参考文献


    参考文献:10.1248/cpb.50.515
    摘要:Anis I, Ahmed S, Malik A, Yasin A, Choudary MI. Enzyme inhibitory constituents from Duranta repens. Chem Pharm Bull (Tokyo). 2002 Apr;50(4):515–8. doi: 10.1248/cpb.50.515.
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