CAS: 24404-49-7; 2-(4-(4-(4-Hydroxy-3-Methoxyphenyl)Tetrahydro-1H,3H-Furo[3,4-C]Furan-1-yl)-2-Methoxyphenoxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol

该化合物是天然形成的液态胶质,来源于Eucommia ulmoides和Forsythia 物种,其特征为与葡萄糖粘合在一起的皮质醇核心,增强了其溶解性和生物利用率,显示了显著的生物活动,包括抗氧化剂,抗炎和潜在的...

英文名称2-(4-(4-(4-Hydroxy-3-Methoxyphenyl)Tetrahydro-1H,3H-Furo[3,4-C]Furan-1-yl)-2-Methoxyphenoxy)-6-(Hydroxymethyl)Tetrahydro-2H-Pyran-3,4,5-Triol
中文名称松脂醇 β-D-吡喃葡萄糖苷
IUPAC名称2-(4-(4-(4-hydroxy-3-methoxyphenyl)tetrahydro-1H,3H-furo[3,4-c]furan-1-yl)-2-methoxyphenoxy)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol
其它别名Epipinoresinol-4-O-Beta-D-Glucoside; β-D-Glucopyranoside, 2-Methoxy-4-[(1S,3Ar,4R,6Ar)-Tetrahydro-4-(4-Hydroxy-3-Methoxyphenyl)-1H,3H-Furo[3,4-C]Furan-1-Yl]Phenyl; Epipinoresinol-4'-O-β-D-Glucoside; Epipinoresinol-4-O-Glucopyranosid; B-D-Glucopyranoside,2-Methoxy-4-[(1S,3Ar,4R,6Ar)-Tetrahydro-4-(4-Hydroxy-3-Methoxyphenyl)-1H,3H-Furo[3,4-C]Furan-1-Yl]Phenyl; Simplocosin
CAS编号24404-49-7
MFCD编号:MFCD34568105
分子式:C26H32O11分子量:520.53
产品CID: 1191542
产品分类医药中间体 → 吡喃类化合物

相似结构搜索
InChIKey: QLJNETOQFQXTLI-UHFFFAOYSA-N
InChI=1S/C26H32O11/c1-32-18-7-12(3-5-16(18)28)24-14-10-35-25(15(14)11-34-24)13-4-6-17(19(8-13)33-2)36-26-23(31)22(30)21(29)20(9-27)37-26/h3-8,14-15,20-31H,9-11H2,1-2H3
计算化学: 氢键受体数11.0氢键供体数5.0可旋转键数7.0

MSDS等安全信息

警示词warning
危险描述H303+H313+H333
防范说明P264Thoroughly clean after treatmentP280Wear protective gloves/Wear protective clothing/Wear protective goggles/Wear a protective maskP305If it enters the eyesP351Rinse carefully with water for a few minutesP338Remove the contact lens(If any)And easy to operate,Continue flushingP337If eye irritation persistsP313Obtain medical advice/care
安全声明H303+H313+H333

上下游产品

Acetic acid (2S,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-{4-[(1S,3aR,4S,6aR)-4-(4-hydroxy-3-methoxy-phenyl)-tetrahydro-furo[3,4-c]furan-1-yl]-2-methoxy-phenoxy}-tetrahydro-pyran-3-yl ester coniferal alcohol (+/-)-pinoresinol (+)-pinoresinol 4-O-[6''-O-galloyl]-β-D-glucopyranoside(3R,4S,5S,6R)-2-{4-[(1S,3aR,4S,6aR)-4-(3,4-Dimethoxy-phenyl)-tetrahydro-furo[3,4-c]furan-1-yl]-2-methoxy-phenoxy}-6-hydroxymethyl-tetrahydro-pyran-3,4,5-triol pinoresinol D-Glucose (+)-pinoresinol-O-β-D-glucopyranoside peracetylated

合成工艺路线路线简述

📜(+)-Pinoresinol 4-O-[6''-O-Galloyl]-β-D-Glucopyranoside置于sodium Methylate体系中,用甲醇用作溶剂,化学反应 1.0H,以1.7 Mg的收率获得松脂醇-4-O-Beta-D-吡喃葡萄糖苷
参考文献:(+)-松脂醇 4-O-[6″-O-Galloyl]-β-D-吡喃葡萄糖苷,Macarangiosides E 和 F 的绝对构型从 Macaranga Tanarius 的叶子中分离出来
标题:(+)-松脂醇 4-O-[6″-O-Galloyl]-β-D-吡喃葡萄糖苷,Macarangiosides E 和 F 的绝对构型从 Macaranga Tanarius 的叶子中分离出来
摘要:一种木脂素葡萄糖苷,(+)-松脂醇 4-O-[6''-O-没食子酰]-β-D-吡喃葡萄糖苷 (1) 和两种名为 Macarangiosides E 和 F (2,3) 的 Megastigmane 葡萄糖苷,以及从 Macaranga Tanarius (L.) Müll.-Arg 的叶子中分离出 15 种已知化合物 (4-18).(大戟科).通过光谱和化学分析阐明了它们的结构.此外,还首次确定了先前从同一植物中分离的 Macarangiosides B 和 C 的绝对立体化学.化合物 1 和 2 在葡萄糖上进行了没食子酰化并具有有效的 Dpph 自由基清除活性.
Doi:10.1016/j.Phytochem.2009.07.020