专利号:US-11655264-B2 优先权日:2015-11-25 标题:Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil 发明人:WEI DONGCHU; LI BING 权利人:APALENE TECH CO LTD JIAXING 摘要:The present invention relates to a metallocene compound, and preparation and use thereof, and the compound can be used as a catalyst for synthesis of poly-α-olefin as lubricating base oil. The metallocene compound includes a substituted aryl group, a bridged atom, an optionally unsubstituted, 3-mono-substituted or 3,6-disubstituted 5H-indeno [1,2-b] pyridyl group or optionally unsubstituted, 3-mono-substituted or 3,6-disubstituted 5H-indeno [1,2-b] thiopyranyl group, and a metal coordination group. As a catalyst, the metallocene compound is shown to be structurally stable and high in catalytic efficiency, and the preparation of the catalyst is relatively easy in operation, high in yield, low in cost, low in pollution and easy to scale up for industrial production.
专利号:US-6387893-B1 优先权日:1999-09-30 标题 :Spirotricyclic substituted azacycloalkane derivatives and uses thereof 发明人:EVANS BEN E; HOFFMAN JACOB M; GILBERT KEVIN F; RITTLE KENNETH E 权利人:MERCK & CO INC 摘要:Spirotricyclic azacycloalkyl compounds and pharmaceutically acceptable salts thereof are disclosed. The synthesis of these compounds is also described. One application of these compounds, which are alpha 1a adrenergic receptor antagonists, is in the treatment of benign prostatic hyperplasia. These compounds are selective in their ability to relax smooth muscle tissue enriched in the alpha 1a receptor subtype without at the same time inducing hypotension. One such tissue is found surrounding the urethral lining. Therefore, one utility of the instant compounds is to provide acute relief to males suffering from benign prostatic hyperplasia, by permitting less hindered urine flow. Another utility of the instant compounds is provided by combination with a human 5-alpha reductase inhibitory compound, such that both acute and chronic relief from the effects of benign prostatic hyperplasia can be achieved.
专利号:US-2018258112-A1 优先权日:2015-11-25 标题 :Metallocene compounds, and preparation and use thereof for synthesis of poly-alpha-olefins as lubricating base oil
参考标题:Scope Of Regioselective Suzuki Reactions In The Synthesis Of Arylpyridines And Benzylpyridines And Subsequent Intramolecular Cyclizations To Azafluorenes And Azafluorenones 作者:Joydev K. Laha,Ketul V. Patel,Saima Saima,Surabhi Pandey,Ganesh Solanke,Vanya Vashisht 摘要:Current Investigation On Regioselective Suzuki Reactions Of 2,3-Dihalopyridines And 2-Halo-3-Halomethylpyridines Yielded The Unexplored Synthesis Of Arylpyridines And Benzylpyridines Bearing Synthetic Handles For Further Functionalization. Indeed, The Scope Of Intramolecular Cyclizations Of Arylpyridines And Benzylpyridines Prepared In This Study For The Synthesis Of Azafluorenes And Azafluorenones Has Been
合成参考文献
参考文献:10.1134/s1070428024110022 摘要:Rakhimova EB, Kirsanov VY. Recent Advances in (Di)Azafluorene Chemistry (A Review). Russ J Org Chem. 2024 Nov;60(11):2086–107. doi: 10.1134/s1070428024110022.