CAS: 143-71-5; (4R,4Ar,7Ar,12Bs)-9-Methoxy-3-Methyl-1,2,4,4A,5,6,7A,13-Octahydro-4,12-Methanobenzofuro[3,2-E]Isoquinoline-7-One,(2R,3R)-2,3-Dihydroxybutanedioic Acid

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CAS号87-69-4 酒石酸 | CAS号125-29-1 氢可酮 | CAS号125-29-1 氢可酮

合成工艺路线路线简述

    📜蒂巴因置于盐酸,C.I.酸性橙108,对甲苯磺酰肼体系中,用 水 用作溶剂,化学反应 4.17H,反应生成重酒石酸二氢可待因酮
    参考文献: Processes For Making Hydrocodone,Hydromorphone And Their Derivatives[fr] Procedes Pour La Fabrication De D'Hydrocodone,D'Hydromorphone Et De Leurs Derives
    标题: Processes For Making Hydrocodone,Hydromorphone And Their Derivatives[fr] Procedes Pour La Fabrication De D'Hydrocodone,D'Hydromorphone Et De Leurs Derives
    摘要:公开了制备羟考酮和羟吗啡以及它们的8,14-二氢茵巴因和8,14-二氢奥利帕温衍生物和盐的改进工艺.

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    专利信息


    专利号:US-6350612-B1
    优先权日:1986-01-28
    标 题 :Isolation and expression of DNA sequence encoding the five subunits of Bordetella pertussis toxin
    发明人:RAPPUOLI RINO; NICOSIA ALFREDO; ARICO MARIA BEATRICE
    权利人:CHIRON SPA
    摘要:Cloning and sequencing of the Eco RI fragment of B. pertussis chromosomal DNA with 4696 base pairs, containing the genes which code for the five subunits of the pertussis toxin. A hybrid plasmid containing the DNA fragment or its further fragments and a micro-organism transformed by the hybrid plasmid and capable of expressing the cloned DNA fragment or further fragments thereof by synthesis of the pertussis toxin or one or more subunits of the pertussis toxin. The pertussis toxin or one or more subunits of the pertussis toxin so obtained are useful for the preparation of vaccines and diagnostic kits.

    专利号:WO-02055432-A1
    优先权日:2001-01-10
    标 题:Method of synthesizing of nanosize carbides and active catalysts__________________________________________________________________ ___________________________________________
    发明人:MALKHASYAN RAZMIK; GARIBYAN TAMARA; GRIGORYAN SUSANNA; KAMANCHAJYAN SERGO; VARTIKYAN LEVON; GRIGORYAN RITA; MINASYAN VARIA
    权利人:MALKHASYAN RAZMIK; GARIBYAN TAMARA; GRIGORYAN SUSANNA; KAMANCHAJYAN SERGO; VARTIKYAN LEVON; GRIGORYAN RITA; MINASYAN VARIA
    摘要:The invention refers to the sphere of material science, nanotechnology and catalysis. The aim of the suggestion invention is to create the method of obtaining of the active nanosize amorphous catalysts and carbides on their basis, to increase the effectiveness and profitableness of the processes of their synthesis. It is worked out the method of obtaining of the amorphous single component metals, putting on the different supporters with the large specific surface. The Indicated metals Mo, W, Cu, etc., as well as their carbides has displayed the high catalitic activity, similar to the metals of platinum group. The applying of the amorphous nanosize metals in the process of their carbidization allowed to lower the temperature and to shorten sharply the time of their synthesis, and just that raises the profitableness of the processes of their synthesis.

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    ✅ COA系统入驻 | 共享模式

    合成参考文献


    参考文献:10.1007/bf02234622
    摘要:Wasvary HJ, Hain J, Mosed-Vogel M, Bendick P, Barkel DC, Klein SN. Randomized, prospective, double-blind, placebo-controlled trial of effect of nitroglycerin ointment on pain after hemorrhoidectomy. Dis Colon Rectum. 2001 Aug;44(8):1069–73. doi: 10.1007/bf02234622.
    参考文献:10.1177/2168479017723399
    摘要:Borders-Hemphill V, Chan IZ, Brown K, Rider B, Taylor K, Chai G. Use of Proprietary Names by Prescribers for Generic Products. Therapeutic Innovation & Regulatory Science. 2018 Mar;52(2):256–60. doi: 10.1177/2168479017723399.
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