CAS: 80506-64-5; Amino Polyethylene Glycol Monomethyl Ether-Average M.W. 2000

该化合物是一个多用途的化合物,其特点是其聚醚结构,由重复的乙烯甘醇单位组成,该化合物的特点是氨基基氨基酯组和一个甲基醚功能组,有助于其在水和各种有机溶剂中的水利和溶解性;其分子结构允许其作为表面活性剂,乳化剂或分散剂在各种应用中发挥作用,包括药物,化妆品和工业配方;氨基化合物的存在增强了其再活动性,使其能够参与各种化学反应,例如结对和交叉连接;此外,氨基(乙基甘醇)甲基醚的毒性和生物兼容性较低,适合生物医学应用;其特性可以通过修改分子重量和乙烯甘醇单位的比例来调整,允许不同配方的各种功能.

英文名称Amino Polyethylene Glycol Monomethyl Ether-Average M.W. 2000
中文名称甲氧基聚乙二醇氨基分子量:1K
IUPAC名称mPEG-amine Mw2000
其它别名2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71-Tetracosaoxatriheptacontan-73-amine; 2,5,8,11,14,17,20,23,26,29,32,35-Dodecaoxaheptatriacontan-37-amine; 3,6,9,12,15,18,21,24,27,30,33,36-Dodecaoxaheptatriacontan-1-amine; Aminopoly(ethylene glycol) methyl ether; MPEG-NH2; O-(2-Aminoethyl)-O'-methylpolyethylene glycol; Poly(ethylene glycol)2-aminoethyl methyl ether; Polyethylene glycol mono(2-aminoethyl) monomethylether; a-Amino-w-methoxy polyoxyethylene; a-Amino-w-methoxypolyethylene glycol; a-Aminoethyl-w-methoxy polyethylene glycol; a-Methoxy-w-aminopoly(ethylene glycol); a-Methyl-w-aminopoly(oxy-1,2-ethanediyl)
CAS编号80506-64-5
MFCD编号:MFCD00131599
分子式:C5H13NO2
分子量:1000.0
产品CID: 1800314
产品分类首页→产品中心

相似结构搜索
InChIKey: QWCGXANSAOXRFE-UHFFFAOYSA-N
InChI=1S/C5H13NO2/c1-7-4-5-8-3-2-6/h2-6H2,1H3…
计算化学: 氢键受体数13.0氢键供体数1.0可旋转键数35.0

物理性质

熔点58-61 °C(文献)
沸点583.6±45.0 °C at 760 mmHg
闪点291.3±22.4 °C
密度1.1±0.1 g/cm3
PSA:0.0
LogP:-4.59
折射率1.458
蒸汽压0.0±1.6 mmHg at 25°C
溶解性Chloroform (Slightly), Metanol (Slightly)
敏感性如果遵照规格使用和储存则不会分解，未有已知危险反应
外观形态白色至类白色颗粒状固体
储存条件2-8°C
产品应用该化合物用于该化合物用于为PEG包装的荧光珠研究大规模循环性细胞图层流动做好准备.

上下游产品

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合成工艺路线路线简述

三缩四乙二醇置于4-二甲氨基吡啶,氯化亚砜,Sodium Azide,Palladium 10% On Activated Carbon,水,氢气,Sodium Hydride,三乙胺,三苯基膦,Sodium Hydroxide体系中,用四氢呋喃,甲醇,二氯甲烷,水,N,N-二甲基甲酰胺,Mineral Oil 作为反应溶剂,80.0 °C,3.0 Mpa 条件下,反应 18.0H,反应生成氨基十三甘醇单甲醚
参考文献:Development Of A Scalable Process For α-Amino-ω-Methoxyl-Dodecaethylene Glycol
标题:Development Of A Scalable Process For α-Amino-ω-Methoxyl-Dodecaethylene Glycol
摘要:We Have Developed A Process For The Efficient And Scalable Preparation Of Heterofunctionalized Dodecaethylene Glycol From The Readily Available Tetraethylene Glycol And Its Macrocyclic Sulfate. By Employing The Benzyl Group As Both A Protecting Group And A Separative Tag,Multiple Chromatographic Separations Were Avoided. With This Method,Alpha-Amino-Omega-Methyl-Dodecaethylene Glycol Was Prepared On A 53 G Scale With High Purity And 61% Overall Yield In Eight Steps And One Chromatographic Separation.
DOI:10.1021/acs.Oprd.5B00270