CAS: 778-25-6; Methyldiphenylsilanol

上下游产品

chloromethyldiphenylsilane ethoxy(methyl)(diphenyl)silane Methyldiphenylsilyl acetate methyldiphenylsilane2-(1,1,3-Trimethyl-3,3-diphenyl-disiloxanylmethoxy)-ethanol Dimethylphosphonigsaeure-(1,2-dimethyl-3,3-diphenyl-1-(methyl-diphenyl-siloxy)-disiloxanyl)-methylester 2,2-dimethyl-1,3-bis-(1,1,3-trimethyl-3,3-diphenyl-disiloxanyl)-[1,3,2]diazasilolidine 3,3'-bis-(1,1,3-trimethyl-3,3-diphenyl-disiloxanyl)-2,2,2',2'-tetramethyl-1,1'-dimethylsilanediyl-bis-[1,3,2]diazasilolidine

甲基二苯基乙氧基硅烷置于水体系中,用 乙腈 作为反应溶剂,化学反应 0.33H,以100%的收率获得产物甲基二苯基硅烷醇
参考文献:シラノール類の製造方法および新規なシラノール類
标题:シラノール類の製造方法および新規なシラノール類
摘要:这是一种制造有用的硅醇类化学品的方法和提供新型硅醇类的解决方案.将具有si-O-R键(其中r表示碳数为1-6的烃基)的烷氧基硅烷类与水或重水,在催化剂存在下进行反应的反应步骤包括在内的硅醇类制造方法,其中所述催化剂是具有规则孔结构的无机固体酸催化剂,其特征在于具有si-O-R'键(其中r'表示氢原子或重氢原子)的硅醇类的制造方法,以及由此获得的新型硅醇类.[选择图]无

专利信息

专利号:US-8492390-B2
优先权日:2002-05-08
标题 :Synthesis of locked nucleic acid derivatives
发明人：DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER
权利人:DETLEF SORENSEN MADS; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER; SANTARIS PHARMA AS
摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as α- L -oxy-LNA, amino-LNA, α- L -amino-LNA, thio-LNA, α- L -thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues.

专利号:EP-1501848-B1
优先权日:2002-05-08
标 题 :Synthesis of locked nucleic acid derivatives
发明人：SORENSEN MADS DETLEF; WENGEL JESPER; KOCH TROELS; CHRISTENSEN SIGNE M; ROSENBOHM CHRISTOPH; PEDERSEN DANIEL SEJER
权利人:SANTARIS PHARMA AS
摘要:The invention relates to a novel strategy for the synthesis of Locked Nucleic Acid derivatives, such as alpha-L-oxy-LNA, amino-LNA, alpha-L-amino-LNA, thio-LNA, alpha-L-thio-LNA, seleno-LNA and methylene LNA, which provides scalable high yielding reactions utilising intermediates that also can produce other LNA analogues such as oxy-LNA. Also, the compounds of the formula X are important intermediates that may be reacted with varieties of nucleophiles leading to a wide variety of LNA analogues. (Formula I)

专利号:US-2004014959-A1
优先权日:2002-05-08
标题:Synthesis of locked nucleic acid derivatives

专利号:EP-1501848-A1
优先权日:2002-05-08
标 题:Synthesis of locked nucleic acid derivatives

专利号:US-8084458-B2
优先权日:2002-05-08
标 题:Synthesis of locked nucleic acid derivatives

专利号:US-2012165514-A1
优先权日:2002-05-08
标 题 :Synthesis of locked nucleic acid derivatives