CAS: 333-47-1; 4-(Trifluoromethylthio)Bromobenzene

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CAS号2314-97-8 三氟碘甲烷 | CAS号106-53-6 4-溴苯硫酚 | CAS号5467-74-3 4-溴苯硼酸 | CAS号2923-18-4 三氟乙酸钠 | CAS号81290-20-2 (三氟甲基)三甲基硅烷 | CAS号5335-84-2 双(4-溴苯基)二硫醚 | CAS号76-05-1 三氟乙酸(TFA) | CAS号75-63-8 三氟溴甲烷 | CAS号108-86-1 溴苯 | CAS号421-17-0 三氟甲基硫氯 | CAS号1005206-25-6 三氟甲硫基-4-(4,4,5,... | CAS号330-17-6 4-(三氟甲基硫代)苯甲酸 | CAS号312-20-9 1-溴-4-((三氟甲基)磺酰基)苯

📜对三氟甲硫基苯胺 反应生成1-溴-4-(三氟甲基硫代)苯
参考文献:甲基和乙基 β-酮酯的选择性转酯化
标题:甲基和乙基 β-酮酯的选择性转酯化
摘要:酯交换是最有效的酯合成方法之一,在学术和工业研究中都有广泛的应用.一般来说,它会被质子酸,"路易斯酸"和碱性催化剂加速.最近已经报道了各种催化剂来实现酯交换.P-酮酯,一类广泛用于农业,制药和染料行业的多功能中间体是合成复杂天然产物的有用且重要的组成部分.2 已经报道了各种制备方法,主要涉及酯衍生物作为起始材料^.^.^ 大多数报道的 P-酮酯酯交换方法并不通用和是平衡驱动的反应,需要过量的一种反应物才能获得非常好的收率.例如,4-(二甲基1氨基)吡啶(dmap)催化酯交换需要大量催化剂,而其他方法仅限于叔丁酯,因此缺乏通用性.尽管二锡氧烷导致 P-酮酯的收率非常好,但催化剂制备困难.具有显着细胞毒活性的木脂素内酯的合成需要大量的各种烷基苯甲酰乙酸酯.然而,关于合成的报道很少.具有显着细胞毒活性的木脂素内酯的合成需要大量的各种烷基苯甲酰乙酸酯.然而,关于合成的报道很少.具有显着细胞毒活性的木
Doi:10.1080/00304940309355835

专利信息

专利号:US-4446078-A
优先权日:1982-01-21
标 题 :Process for the preparation of α,α-difluoroalkyl-thiophenyl ketones
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of alpha , alpha -difluoroalkoxy or alpha , alpha -difluoroalkylthiophenyl ketones, in which a polyhaloalkoxybenzene or a polyhaloalkylthiobenzene is reacted with a carboxylic acid, a precursor or a derivative of this acid in the presence of boron trifluoride in such an amount that the absolute pressure of the boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent. The resultant products are useful as intermediates in the synthesis of compounds having phytosanitary (e.g., herbicidal) or pharmaceutical activity.

专利号:US-4552984-A
优先权日:1982-01-21
标题 :Process for preparation of α,α-difluoroalkoxy or α,.alpha.
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of alpha , alpha -difluoroalkoxy or alpha , alpha -difluoroalkylthiophenyl sulfones, in which a polyhaloalkoxybenzene or a polyhaloalkylthiobenzene is reacted with a sulfonic acid, a derivative or a precursor of this acid, in the presence of boron trifluoride in an amount such that the absolute pressure of the boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent. The resultant products are useful as intermediates in the synthesis of compounds having a phytosanitary (e.g., herbicidal) or pharmaceutical activity.

专利号:US-4438043-A
优先权日:1982-04-22
标题:Process for preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones
发明人：DESBOIS MICHEL
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the preparation of di- or trifluoromethoxyphenyl ketones or di- or trifluoromethylthiophenyl ketones, characterized in that, in a first stage, a di- or trihalomethoxybenzene or a di- or trihalomethylthiobenzene is reacted with a trihalomethylated aromatic or aliphatic compound in the presence of boron trifluoride in an amount such that the absolute pressure of boron trifluoride within the reaction vessel exceeds 1 bar, and in the presence of hydrofluoric acid as a solvent and in that, in a second stage, the product of the first stage is hydrolyzed. The resultant products are useful as intermediates in the synthesis of compounds having a pharmaceutical or phytosanitary (e.g., herbicidal) activity.

专利号:US-4575571-A
优先权日:1983-06-23
标题:Process for the simultaneous halogenation and fluorination of aromatic derivatives
发明人：DESBOIS MICHEL; DISDIER CAMILLE
权利人:RHONE POULENC SPEC CHIM
摘要:A process for the stimulaneous halogenation and fluorination of aromatic derivatives substituted by at least one group containing a halogenoalkyl unit. The aromatic derivative is reacted with the halogen in liquid hydrofluoric acid. The products obtained are useful as intermediates for the synthesis of compounds having a plant-protecting or pharmaceutical activity.

专利号:US-2007275968-A1
优先权日:2004-09-07
标 题 :Substituted Biphenyl Derivative
发明人：KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
权利人:KURATA HITOSHI; NISHIMATA TOYOKI; WATANABE YUKIKO; EBISAWA MASAYUKI; FUJIMOTO TEPPEI; KOBAYASHI HIDEKI
摘要:The present invention relates to a biaryl derivative or a pharmacologically acceptable salt thereof having an excellent collagen-synthesis inhibition activity. A biaryl derivative having a structure represented by the following General Formula (I) or a pharmacologically acceptable salt thereof: n nwherein n R 1 represents a C 6 -C 10 aryl group which is substituted with one to three group(s) each independently selected from the group consisting of a group defined by formula R-L-, a di-(C 1 -C 6 alkyl)amino group, a di-(C 1 -C 6 alkyl)aminosulfonyl group, a hydroxyaminocarbonyl group, and a halogen atom, and so on; R represents a C 1 -C 6 alkyl group, and so on; L represents a sulfonyl group, an aminosulfonyl group, or a sulfonylamino group, and so on; R 2 represents a hydrogen atom, and so on; A represents a group defined by formula (II), (III), or (IV); R 3 represents a C 1 -C 6 alkyl group, and so on; and R 4 represents a C 1 -C 6 alkyl group, and so on.